Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Denise Jaggers"'
Autor:
Eric M Thompson, Daniel Landi, Michael C Brown, Henry S Friedman, Roger McLendon, James E Herndon, Evan Buckley, Dani P Bolognesi, Eric Lipp, Kristin Schroeder, Oren J Becher, Allan H Friedman, Zachary McKay, Ashley Walter, Stevie Threatt, Denise Jaggers, Annick Desjardins, Matthias Gromeier, Darell D Bigner, David M Ashley
Publikováno v:
The Lancet Child & Adolescent Health.
Autor:
Eric Thompson, Daniel Landi, Michael Brown, Henry S Friedman, Roger McLendon, Dani Bolognesi, Kristin Schroeder, Oren Becher, Allan Friedman, Ashley Walter, Stevie Threatt, Denise Jaggers, Annick Desjardins, Matthias Gromeier, Darell Bigner, David Ashley
Publikováno v:
Neuro-Oncology. 24:vii62-vii63
BACKGROUND Outcomes of recurrent pediatric high grade glioma (pHHG) are poor with a median overall survival (OS) of < 6 months. Viral immunotherapy such as the polio:rhinovirus chimera, PVSRIPO, is a novel treatment approach for recurrent pHHG. PVSRI
Autor:
Kirit Singh, Matthew Foster, Elizabeth S. Miller, Simon Gregory, Kent J. Weinhold, David M. Ashley, Annick Desjardins, Justin Low, Katherine B. Peters, Erin Severance, Denise Jaggers, Henry S. Friedman, Margaret O. Johnson, Allan H. Friedman, Stephen T. Keir, James Emmett Herndon, Chuan-Yuan Li, Peter E. Fecci, John H. Sampson, Mustafa Khasraw
Publikováno v:
Journal of Clinical Oncology. 40:TPS2076-TPS2076
TPS2076 Background: High-grade gliomas (HGGs) are immunologically ‘cold’ tumors. This phenomenon is partly due to reduced expression of major histocompatibility class (MHC) I on the surface of tumor cells, which prevents CD8+ cytotoxic T lymphocy
Autor:
Katherine B. Peters, Aditya Mohan, Weihua Xie, David M. Ashley, Pamela Norberg, Gary E. Archer, Elizabeth A. Reap, Gordana Vlahovic, Annick Desjardins, Kristen A. Batich, Henry S. Friedman, Denise Jaggers, Hai Yan, Mustafa Khasraw, James E. Herndon, Kendra L. Congdon, Margaret Johnson, Daniel Landi, John Sampson, Kelly Hotchkiss
Publikováno v:
Neuro-Oncology Advances. 3:iv5-iv6
INTRODUCTION While primary GBM is largely heterogeneous and devoid of homogeneously expressed neoantigens, mutant IDH1 (R132H) is a uniformly expressed hallmark in >70% of low grade gliomas. As such, IDH1 mutations represent a potentially valuable va
Autor:
Brian J. Soher, Gordana Vlahovic, Eric S. Lipp, Hai Yan, James E. Herndon, Henry S. Friedman, Dina Randazzo, Margaret Johnson, Patrick Healy, John Sampson, Sarah Woodring, Denise Jaggers, Gary E. Archer, David M. Ashley, Kendra L. Congdon, Annick Desjardins, Allan H. Friedman, Katherine B. Peters
Publikováno v:
Neuro Oncol
BACKGROUND Low grade gliomas (LGGs) represent 10–15% of glial tumors in adults and while LGG patients have a better prognosis over high-grade gliomas, these cancers ultimately recur and transform to more aggressive tumors. Isocitrate dehydrogenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e039c8d1f62cfb3c174ed70c132e7a
https://europepmc.org/articles/PMC6847076/
https://europepmc.org/articles/PMC6847076/
Autor:
Eric Thompson, Daniel Landi, Gerald Archer, Eric Lipp, Ashley Walter, Bridget Archambault, Bea Balajonda, Charlene Flahiff, Denise Jaggers, James Herndon, Evan Buckley, Kristin Schroeder, Dina Randazzo, Annick Desjardins, Margaret Johnson, Katherine Peters, Mustafa Khasraw, Michael Malinzak, Duane Michell, David Ashley, John Sampson
Publikováno v:
Neuro-Oncology
Introduction The cytomegalovirus (CMV) antigen, pp65, is ubiquitously expressed in malignant glioma and medulloblastoma but not in healthy brain. The objective of this Phase I trial (NCT03299309) was to assess the safety and feasibility of a novel pp
Autor:
Frances McSherry, Katherine B. Peters, Denise Jaggers, Gary E. Archer, Rachael Van, Sarah Gemberling, Kendra L. Congdon, David M. Ashley, Pam Norberg, Kristen A. Batich, Jordan Parker, Annick Desjardins, Luis Sanchez-Perez, Rachel Hesler, James E. Herndon, John Sampson, Henry S. Friedman
Two of our previous clinical trials targeting Cytomegalovirus (CMV) protein pp65 in newly diagnosed glioblastoma (GBM) using pp65-specific dendritic cell (DC) vaccines have yielded long term survival rates greatly exceeding those predicted with stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2dd4e06ff2fa8dc289050862cc703a6
https://europepmc.org/articles/PMC6217626/
https://europepmc.org/articles/PMC6217626/
Autor:
James E. Herndon, Kristin Schroeder, Gary E. Archer, John Sampson, Charlene Flahiff, Denise Jaggers, Eric S. Lipp, Timothy A. Driscoll, Eric M. Thompson, Bridget Archambault, Daniel Landi, Patrick Healy, Luis Ramirez, Kathleen Hahn, David M. Ashley
Publikováno v:
Neuro-Oncology
BACKGROUND Recurrent medulloblastoma and malignant glioma are lethal tumors that are virtually incurable. The cytomegalovirus (CMV) antigen pp65 is ubiquitously expressed on medulloblastoma and malignant glioma but not on healthy brain. We evaluated
Autor:
John Sampson, James E. Herndon, Katherine B. Peters, Kristin Schroeder, Denise Jaggers, Eric S. Lipp, Gerald E. Archer, Duane Michell, Charlene Flahiff, Annick Desjardins, Ashley Walter, Bea Balajonda, Daniel Landi, Mustafa Khasraw, Bridget Archambault, Eric M. Thompson, Michael D. Malinzak, David M. Ashley, Evan Buckley, Margaret Johnson, Dina Randazzo
Publikováno v:
Neuro-Oncology
INTRODUCTION The cytomegalovirus (CMV) antigen, pp65, is ubiquitously expressed in malignant glioma and medulloblastoma but not in healthy brain. The objective of this Phase I trial (NCT03299309) was to assess the safety and feasibility of a novel pp
Autor:
Anna M. Baker, Janet T. Holbrook, Abebaw M. Yohannes, Michelle N. Eakin, Elizabeth A. Sugar, Robert J. Henderson, Anne S. Casper, David A. Kaminsky, Alexis L. Rea, Anne M. Mathews, Loretta G. Que, Joe W. Ramsdell, Lynn B. Gerald, Robert A. Wise, Nicola A. Hanania, Nicola Hanania, Marianna Sockrider, Laura Bertrand, Mustafa Atik, Blanca A. Lopez, Joan Reibman, Emily DiMango, Linda Rogers, Karen Carapetyan, Kristina Rivera, Melissa Scheuerman, Elizabeth Fiorino, Newel Bryce-Robinson, Deanna Green, Robert Noveck, Catherine Foss, Jessica Ghidorzi, Zongyao Wang, Elise Pangborn, V. Susan Robertson, Nicholas Eberlein, Jane Stiles, Michael Land, Brian Vickery, Eveline Wu, Denise Jaggers, Stephanie Allen, Sabrena Mervin-Blake, Lewis Smith, Ravi Kalhan, James Moy, Edward Naureckas, Jenny Hixon, Zenobia Gonsalves, Virginia Zagaja, Jennifer Kustwin, Ben Xu, Thomas Matthews, Lucius Robinson, Noopur Singh, Kyle Happel, Marie C. Sandi, Jennifer M. Graham, Katelyn Sullivan, Elizabeth Poretta, Rohit Katial, Flavia Hoyte, Maria Rojas, Mario Castro, Leonard B. Bacharier, Kaharu Sumino, Roger D. Yusen, Jaime J. Tarsi, Brenda Patterson, Terri Montgomery, Michael Busk, Debra Weiss, Kimberly Sundblad, Charles Irvin, Anne E. Dixon, Charlotte Teneback, Jothi Kanagalingam, Stephanie M. Burns, Kathleen Dwinell, James L. Goodwin, Mark A. Brown, Tara F. Carr, Cristine E. Berry, Christian Bime, Mark A. Goforth, Elizabeth A. Ryan, Jesus A. Wences, Silvia L. Lopez, Janette C. Priefert, Natalie S. Provencio-Dean, Destinee R. Ogas, Valerie R. Bloss, Stephen I. Wasserman, Xavier T. Soler, Katie H. Kinninger, Amber J. Martineau, Tonya Greene, Samang Ung, Adam Wanner, Richard Lockey, Thomas B. Casale, Andreas Schmid, Michael Campos, Monroe King, Eliana S. Mendes, Catherine Renee Smith, Jeaneen Ahmad, Patricia D. Rebolledo, Johana Arana, Lilian Cadet, Shawna Atha, Rebecca McCrery, Sarah M. Croker, Gary Salzman, Asem Abdeljalil, Abid Bhat, Ashraf Gohar, Mary Reed, W. Gerald Teague, Larry Borish, Kristin W Wavell, Theresa A. Altherr, Donna Wolf, Shahleen Ahmed, William C. Bailey, Robert Wise, Janet Holbrook, Alexis Rea, Joy Saams, Bethany Grove, Adante Hart, Andrea Lears, Deborah Nowakowski, David Shade, Elizabeth Sugar, Anne Shanklin Casper, Lea T. Drye, Vernon M. Chinchilli, Paul N. Lanken, Donald P. Tashkin, Alexandra Sierra, Norman H. Edelman, Susan Rappaport, Elizabeth Lancet
Publikováno v:
Ann Am Thorac Soc
Rationale: Anxiety is a common comorbidity of chronic obstructive pulmonary disease (COPD) that is associated with higher morbidity and mortality. We evaluated three anxiety screening questionnaires: the Generalized Anxiety Disorder 7-Item Scale (GAD