Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Denise Imai"'
Autor:
Beltran Borges, Antonia Varthaliti, Marisa Schwab, Maria T. Clarke, Christopher Pivetti, Nalin Gupta, Cathryn R. Cadwell, Ghiabe Guibinga, Shirley Phillips, Tony Del Rio, Fatih Ozsolak, Denise Imai-Leonard, Lingling Kong, Diana J. Laird, Akos Herzeg, Charlotte J. Sumner, Tippi C. MacKenzie
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101263- (2024)
Prenatal somatic cell gene therapy (PSCGT) could potentially treat severe, early-onset genetic disorders such as spinal muscular atrophy (SMA) or muscular dystrophy. Given the approval of adeno-associated virus serotype 9 (AAV9) vectors in infants wi
Externí odkaz:
https://doaj.org/article/d01f9d171e174897be32403a75098f3a
Autor:
Zhou Jiang, Juan Wang, Denise Imai, Tim Snider, Jenna Klug, Ruby Mangalindan, John Morton, Lida Zhu, Adam B. Salmon, Jackson Wezeman, Jiayi Hu, Vinal Menon, Nicholas Marka, Laura Neidernhofer, Warren Ladiges
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs targeting different but overlapping processes. In order to determine if combining drugs shown to extend lifespan
Externí odkaz:
https://doaj.org/article/db55d8a2d1a2428eac1def333721ab8d
Resurgence of persisting non-cultivable Borrelia burgdorferi following antibiotic treatment in mice.
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86907 (2014)
The agent of Lyme borreliosis, Borrelia burgdorferi, evades host immunity and establishes persistent infections in its varied mammalian hosts. This persistent biology may pose challenges to effective antibiotic treatment. Experimental studies in dogs
Externí odkaz:
https://doaj.org/article/1a832496e43d4b44ac6501bc2fc9a9ba
Autor:
Zhou Jiang, Juan Wang, Denise Imai, Tim Snider, Jenna Klug, Ruby Mangalindan, John Morton, Lida Zhu, Adam B. Salmon, Jackson Wezeman, Jiayi Hu, Vinal Menon, Nicholas Marka, Laura Neidernhofer, Warren Ladiges
Publikováno v:
Scientific reports. 12(1)
Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs targeting different but overlapping processes. In order to determine if combining drugs shown to extend lifespan and heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9721703b797603f2c7639c9727f75d
https://pubmed.ncbi.nlm.nih.gov/35508491
https://pubmed.ncbi.nlm.nih.gov/35508491
Autor:
Michael Ellis, Adam Sanmiguel, Richard D. French, Jason Serrano, Denise Imai, Andy Schile, Krystal Leighton
Publikováno v:
Diabetes. 69
Nonalcoholic steatohepatitis (NASH) is usually diagnosed in 40-60 year old patients with metabolic syndrome, but many common mouse models involve dietary or chemical interventions that begin at young ages. We established 3 NASH models using year-old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4805a10f50db14a1564dca5952d42bdc
https://doi.org/10.2337/db20-1842-p
https://doi.org/10.2337/db20-1842-p
Autor:
N. Szigetvari, Lucas Campos de Sá Rodrigues, Esther Chon, Caroline M. Piskun, Timothy J. Stein, Denise Imai
Publikováno v:
Veterinary and Comparative Oncology. 14:225-235
Osteosarcoma is the most common primary malignancy of bone in dogs and is associated with poor long-term outcomes due to its highly metastatic nature. A better understanding of the signalling pathways and proteins involved with osteosarcoma pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8df9b0d7299fb87ab6c93eaa0a73fb71
https://doi.org/10.1111/vco.12073
https://doi.org/10.1111/vco.12073
Autor:
Denise Imai, Christoph Mans
Publikováno v:
Journal of the American Veterinary Medical Association. 244:1243-1245
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c543537dcf65e80ed693a19c5473fd0
https://doi.org/10.2460/javma.244.11.1243
https://doi.org/10.2460/javma.244.11.1243
Publikováno v:
Cancer Research. 78:5113-5113
The C57BL/6J inbred mouse strain is widely used to study the effects of aging. We have documented 51 spontaneous tumors (39 malignant and 12 benign) as part of a recent effort to establish large colonies of male and female C57BL/6J mice for aging res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b9a66e9d3ff1d47431dfa6bd06c4fc6
https://doi.org/10.1158/1538-7445.am2018-5113
https://doi.org/10.1158/1538-7445.am2018-5113
Autor:
Sn, Levoe, Bm, Flannery, Brignolo L, Denise Imai, Koehne A, At, Austin, Da, Bruun, Dj, Tancredi, Pj, Lein
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0031f6333a7415d7e72fb204fb49c796
http://europepmc.org/abstract/med/25705100
http://europepmc.org/abstract/med/25705100
