Výsledky vyhledávání

Akademický článek

Rescue of Alzheimer’s disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells

Autor: Priyanka Mishra, Alexander Silva, Jay Sharma, Jacqueline Nguyen, Donald P. Pizzo, Denise Hinz, Debashis Sahoo, Stephanie Cherqui

Publikováno v: Cell Reports, Vol 42, Iss 8, Pp 112956- (2023)

Summary: Alzheimer’s disease (AD) is the most prevalent cause of dementia; microglia have been implicated in AD pathogenesis, but their role is still matter of debate. Our study showed that single systemic wild-type (WT) hematopoietic stem and prog

Externí odkaz: https://doaj.org/article/a655da2955ba4d05968d702555cfd25e

Zobrazit plný text záznamu

Akademický článek

Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease

Autor: Yuan Tian, Grégory Seumois, Luzia M. De-Oliveira-Pinto, Jose Mateus, Sara Herrera-de la Mata, Cheryl Kim, Denise Hinz, N.D. Suraj Goonawardhana, Aruna D. de Silva, Sunil Premawansa, Gayani Premawansa, Ananda Wijewickrama, Angel Balmaseda, Alba Grifoni, Pandurangan Vijayanand, Eva Harris, Bjoern Peters, Alessandro Sette, Daniela Weiskopf

Publikováno v: Cell Reports, Vol 29, Iss 13, Pp 4482-4495.e4 (2019)

Summary: Dengue virus (DENV) can cause diseases ranging from dengue fever (DF) to more severe dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Whether antiviral T cells contribute to the protection against or pathogenesis of severe disease i

Externí odkaz: https://doaj.org/article/7c7e6719670c412ab9f1987414752616

Zobrazit plný text záznamu

Akademický článek

Allergy-associated T cell epitope repertoires are surprisingly diverse and include non-IgE reactive antigens

Autor: April Frazier, Veronique Schulten, Denise Hinz, Carla Oseroff, John Sidney, Bjoern Peters, Alessandro Sette

Publikováno v: World Allergy Organization Journal, Vol 7, Iss , Pp - (2014)

We recently identified T cell epitopes associated with human allergic responses. In a majority of cases, responses focused on a few immunodominant epitopes which can be predicted on the basis of MHC binding characteristics. Several observations from

Externí odkaz: https://doaj.org/article/5e791b642d404421aad5d00a03b16911

Zobrazit plný text záznamu

Akademický článek

Generation of IL-8 and IL-9 Producing CD4+ T Cells Is Affected by Th17 Polarizing Conditions and AHR Ligands

Autor: Michaela Gasch, Tina Goroll, Mario Bauer, Denise Hinz, Nicole Schütze, Tobias Polte, Dörthe Kesper, Jan C. Simon, Jörg Hackermüller, Irina Lehmann, Gunda Herberth

Publikováno v: Mediators of Inflammation, Vol 2014 (2014)

The T helper cell subsets Th1, Th2, Th17, and Treg play an important role in immune cell homeostasis, in host defense, and in immunological disorders. Recently, much attention has been paid to Th17 cells which seem to play an important role in the ea

Externí odkaz: https://doaj.org/article/193ae502640f462ea12d577b57152413

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání