Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Denise Hertel"'
Autor:
Kris Vaddi, Richard S. Levy, Swamy Yeleswaram, Alice B. Gottlieb, Naresh Punwani, William V. Williams, Paul Collier, Peggy Scherle, Timothy Burn, James D. Rodgers, Patrick J. Haley, Paul Waeltz, Denise Hertel, Robert Flores, Yvonne Lo, Jack G. Shi, Stacey Shepard
Publikováno v:
British Journal of Dermatology. 173:989-997
Background INCB018424 is a novel, potent Janus kinase (JAK)1/JAK2 inhibitor that blocks signal transduction of multiple proinflammatory cytokines. Objectives To evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6a1274a7007b5ad611c053d00bcfc8
https://doi.org/10.1111/bjd.13994
https://doi.org/10.1111/bjd.13994
Autor:
Beth Thomas, Gregory Hollis, Patrick J. Haley, Brian Metcalf, Kris Vaddi, Claire L. Neilan, Jack G. Shi, Paul Collier, Nancy Contel, Steven Friedman, Swamy Yeleswaram, Jordan S. Fridman, Denise Hertel, Robert Collins, Stacey Shepard, Peggy Scherle, Timothy Burn, Robert C. Newton, James D. Rodgers
Publikováno v:
Journal of Investigative Dermatology. 131:1838-1844
JAKs are required for signaling initiated by several cytokines (e.g., IL-4, IL-12, IL-23, thymic stromal lymphopoietin (TSLP), and IFNγ) implicated in the pathogenesis of inflammatory skin diseases such as psoriasis and atopic dermatitis (AD). Direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7345558e130f55ec6c48b0e14482a5
https://doi.org/10.1038/jid.2011.140
https://doi.org/10.1038/jid.2011.140
Autor:
Sang Hyun Lee, Antony Chadderton, Valerie Roman, Wenqing Yao, Gregory F. Hollis, Melody Diamond, Reid Huber, Bruce Ruggeri, Rebecca Stewart, Huiqing Liu, Michael Weber, Liangxing Wu, Julian Oliver, Phillip Liu, Alan Roberts, Denise Hertel, Alla Volgina, Peggy A. Scherle, Swamy Yeleswaram, Chunhong He
Publikováno v:
Cancer Research. 78:3929-3929
The primary cause of cancer associated mortality is tumor metastasis. The concept of the tumor pre-metastatic niche is supported by evidence of changes at distal pre-metastatic sites that create a permissive environment to allow disseminated tumor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a918c951698b59cdcee30676e963d90
https://doi.org/10.1158/1538-7445.am2018-3929
https://doi.org/10.1158/1538-7445.am2018-3929