Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Denise Fedele"'
Autor:
Alessandro Bortolami, Wei Yu, Elena Forzisi, Koray Ercan, Ritik Kadakia, Madhuvika Murugan, Denise Fedele, Irving Estevez, Detlev Boison, Mladen-Roko Rasin, Federico Sesti
Publikováno v:
Cell Death & Differentiation. 30:687-701
Potassium (K+) channels are robustly expressed during prenatal brain development, including in progenitor cells and migrating neurons, but their function is poorly understood. Here, we investigate the role of voltage-gated K+ channel KCNB1 (Kv2.1) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d48e8f56979e3790904044f15d058d
https://doi.org/10.1038/s41418-022-01072-2
https://doi.org/10.1038/s41418-022-01072-2
Autor:
Hoda Gebril, Detlev Boison, Denise Fedele, Kiran S. Toti, Kenneth Alan Jacobson, Amir E. Wahba, Enamr AlHarfoush
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] DNA methylation has a major role in cancer, and its inhibitors are used therapeutically. DNA methylation depends on methyl group flux through the transmethylation pathway, which forms adenosine. We hypothesized that an adenosine kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d168fef9e31c1b8eb10411bd677daaa8
https://doi.org/10.1021/acsptsci.1c00008
https://doi.org/10.1021/acsptsci.1c00008
Publikováno v:
Brain communications. 4(5)
Sudden unexpected death in epilepsy is the leading cause of epilepsy related death. Currently, there are no reliable methods for preventing sudden unexpected death in epilepsy. The precise pathophysiology of sudden unexpected death in epilepsy is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21dbd2781b26c25b8f779007a74a62e0
https://pubmed.ncbi.nlm.nih.gov/36196086
https://pubmed.ncbi.nlm.nih.gov/36196086
Autor:
Benton S. Purnell, Sydney Thompson, Tenise Bowman, Jayant Bhasin, Steven George, Brian Rust, Madhuvika Murugan, Denise Fedele, Detlev Boison
Publikováno v:
Neuropharmacology. 222:109296
Alcohol-related poisoning is the foremost cause of death resulting from excessive acute alcohol consumption. Respiratory failure is crucial to the pathophysiology of fatal alcohol poisoning. Alcohol increases accumulation of extracellular adenosine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e77f1b7dc47126d4bd66bb7180e868
https://doi.org/10.1016/j.neuropharm.2022.109296
https://doi.org/10.1016/j.neuropharm.2022.109296
Autor:
David Millner, Madhuvika Murugan, Denise Fedele, Detlev Boison, Enmar Alharfoush, Geetasravya Vegunta
Publikováno v:
Neurochem Int
Adenosine kinase (ADK) is the key regulator of adenosine and catalyzes the metabolism of adenosine to 5'-adenosine monophosphate. The enzyme exists in two isoforms: a long isoform (ADK-long, ADK-L) and a short isoform (ADK-short, ADK-S). The two isof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c455a1c4617447b41faa62bae7de5e79
https://pubmed.ncbi.nlm.nih.gov/33961946
https://pubmed.ncbi.nlm.nih.gov/33961946
Autor:
Denise Fedele, Vineet C. Chitravanshi, Madhuvika Murugan, Detlev Boison, Trong Huynh, Benton S. Purnell, Omar Ashraf
Publikováno v:
Neuropharmacology
Sudden unexpected death in epilepsy (SUDEP) is a leading cause of death in patients with refractory epilepsy. Centrally-mediated respiratory dysfunction has been identified as one of the principal mechanisms responsible for SUDEP. Seizures generate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f75eb7b3d514b44446edf4838ca1c88
https://pubmed.ncbi.nlm.nih.gov/33212114
https://pubmed.ncbi.nlm.nih.gov/33212114
Autor:
Ana M. Sebastião, Fabio C Tescarollo, Diogo M. Rombo, Lindsay K DeLiberto, Enmar Alharfoush, Detlev Boison, Rodrigo A. Cunha, Denise Fedele, Ângelo R. Tomé
Publikováno v:
J Caffeine Adenosine Res
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© Mary Ann Liebert, Inc.
Adenosine is an endogenous anticonvulsant and neuroprotectant of the brain. Seizure activity produces large quantities of adenosine, and it is this seizure-induced adenosine surge that normally stops a seizure. However,
Adenosine is an endogenous anticonvulsant and neuroprotectant of the brain. Seizure activity produces large quantities of adenosine, and it is this seizure-induced adenosine surge that normally stops a seizure. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8b01a8b213d881d0b3b7351b3b08de
https://europepmc.org/articles/PMC7301316/
https://europepmc.org/articles/PMC7301316/
