Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Denise E, de Almeida"'
Autor:
Denise E. de Almeida Nagata, Eugene Y. Chiang, Suchit Jhunjhunwala, Patrick Caplazi, Vidhyalakshmi Arumugam, Zora Modrusan, Emily Chan, Mark Merchant, Lingyan Jin, David Arnott, F. Anthony Romero, Steven Magnuson, Karen E. Gascoigne, Jane L. Grogan
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 269-281.e4 (2019)
Summary: Myeloid-derived suppressor cells (MDSCs) are found in most cancer malignancies and support tumorigenesis by suppressing immunity and promoting tumor growth. Here we identify the bromodomain (BRD) of CBP/EP300 as a critical regulator of H3K27
Externí odkaz:
https://doaj.org/article/59bed4a4121e435abacf7f0ac7ad65fe
Autor:
Denise E. de Almeida Nagata, Jennifer Vogt, Roxanne Andaya, Helen Booler, Vladimir Bantseev, Chris Schuetz, Chris Lawson, Debby P. Chang
Publikováno v:
Toxicologic Pathology. 49:621-633
Sustained drug delivery formulations are developed to reduce dose frequency while maintaining efficacy of intravitreal (ITV) administered therapeutics. Available safety data for components novel to the eye’s posterior segment may be limited, requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b38c0c483e214753e082c3220193b0a
https://doi.org/10.1177/0192623320971571
https://doi.org/10.1177/0192623320971571
Autor:
Youngsu Kwon, Avantika S. Chitre, Denise E. de Almeida Nagata, Karl L. Banta, Stephanie Mittman, Keith R. Anderson, Rafael Cubas, Kristin Harden Bowles, Patrícia de Almeida, Eugene Y. Chiang, Xiangnan Du, Søren Warming, Jane L. Grogan, Brent S. McKenzie
Publikováno v:
European Journal of Immunology. 50:891-902
CD96 is a member of the poliovirus receptor (PVR, CD155)-nectin family that includes T cell Ig and ITIM domain (TIGIT) and CD226. While CD96, TIGIT, and CD226 have important roles in regulating NK cell activity, and TIGIT and CD226 have also been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ca155c5655ee151dba33f44f53989f
https://doi.org/10.1002/eji.201948405
https://doi.org/10.1002/eji.201948405
Autor:
Ivan Maillard, Andrew J. Rasky, Denise E. de Almeida Nagata, Carrie-Anne Malinczak, Hung-An Ting, Matthew Schaller, Nicholas W. Lukacs
Publikováno v:
Mucosal immunology
Notch ligand Delta-like ligand 4 (DLL4) has been shown to regulate CD4 T-cell differentiation, including regulatory T cells (Treg). Epigenetic alterations, which include histone modifications, are critical in cell differentiation decisions. Recent ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec3a5c4dfaefce9976f585d264b831a
https://doi.org/10.1038/s41385-018-0052-1
https://doi.org/10.1038/s41385-018-0052-1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Matthew Schaller, Denise E. de Almeida Nagata, Andrew J. Rasky, Hung-An Ting, Nicholas W. Lukacs, Ivan Maillard
Publikováno v:
The Journal of Immunology. 198:1492-1502
Regulatory T (Treg) cells establish tolerance, prevent inflammation at mucosal surfaces, and regulate immunopathology during infectious responses. Recent studies have shown that Delta-like ligand 4 (Dll4) was upregulated on APC after respiratory sync
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84a97be160de093da4edf54ab8bec09
https://doi.org/10.4049/jimmunol.1601654
https://doi.org/10.4049/jimmunol.1601654
Autor:
Eugene Y. Chiang, Patricia E. Almeida, Avantika Chitre Elgin, Keith R. Anderson, Stephanie Mittman, Brent S. McKenzie, Xiangnan Du, Youngsu Kwon, Rafael Cubas, Søren Warming, Jane L. Grogan, Karl L. Banta, Denise E. de Almeida Nagata, Kristin Harden Bowles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee61ad8b8710068e3e405e02ca66a42
https://doi.org/10.1002/eji.201948405/v2/response1
https://doi.org/10.1002/eji.201948405/v2/response1
Autor:
Eugene Y, Chiang, Patricia E, de Almeida, Denise E, de Almeida Nagata, Kristin Harden, Bowles, Xiangnan, Du, Avantika S, Chitre, Karl L, Banta, Youngsu, Kwon, Brent, McKenzie, Stephanie, Mittman, Rafael, Cubas, Keith R, Anderson, Søren, Warming, Jane L, Grogan
Publikováno v:
European journal of immunologyReferences. 50(6)
CD96 is a member of the poliovirus receptor (PVR, CD155)-nectin family that includes T cell Ig and ITIM domain (TIGIT) and CD226. While CD96, TIGIT, and CD226 have important roles in regulating NK cell activity, and TIGIT and CD226 have also been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::689896c616bf8c5edd047ab9153ab68a
https://pubmed.ncbi.nlm.nih.gov/32043568
https://pubmed.ncbi.nlm.nih.gov/32043568
Autor:
Hao Cai, Stefan Knackmuss, Steve R. Leong, Luna Liu, Nicholas Corr, Bing Zheng, Shelly Zhong, Lanlan Yu, Thorsten Ross, Uwe Reusch, Christoph Spiess, Michael Dillon, Sivan Cohen, Adeyemi O Adedeji, Satoko Kakiuchi-Kiyota, Susanne Wingert, Andrew Polson, Robert Hendricks, Melissa Schutten, Aaron Fullerton, Denise E. de Almeida Nagata, Ayse M. Ovacik
Publikováno v:
Cancer Research. 80:4556-4556
RO7297089 is a bispecific antibody (IgG-scFv) targeting Bcell maturation antigen (BCMA) and CD16a (FcγRIIIA) that is being developed for the treatment of multiple myeloma (MM). BCMA is exclusively expressed on plasmablasts and differentiated plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdcabaa7f38ccb579429cc4bf922491
https://doi.org/10.1158/1538-7445.am2020-4556
https://doi.org/10.1158/1538-7445.am2020-4556
Autor:
Vidhyalakshmi Arumugam, Xiangnan Du, Jill Schartner, Søren Warming, Keith R. Anderson, Nicholas A. Manieri, Patrícia de Almeida, Jane L. Grogan, Vincent Javinal, Stephanie Mittman, Rafael Cubas, Eugene Y. Chiang, Kristin Harden Bowles, Thomas D. Wu, Denise E. de Almeida Nagata
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance CD226 is an important activating receptor involved in mediating natural killer (NK) cell responses against tumors, but how CD226 exerts control over NK cell function is not fully understood. CD226 belongs to the poliovirus receptor (PVR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180adb1a4f2f78c65e307bbac2abf5d5
https://doi.org/10.1073/pnas.1814052115
https://doi.org/10.1073/pnas.1814052115