Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Denise Dwyer"'
Autor:
Xin Luo, Jun Yin, Denise Dwyer, Tracy Yamawaki, Hong Zhou, Hongfei Ge, Chun-Ya Han, Artem Shkumatov, Karen Snyder, Brandon Ason, Chi-Ming Li, Oliver Homann, Marina Stolina
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Heart failure with reduced ejection fraction (HFrEF) constitutes 50% of HF hospitalizations and is characterized by high rates of mortality. To explore the underlying mechanisms of HFrEF etiology and progression, we studied the molecular and
Externí odkaz:
https://doaj.org/article/633f57b6f6c4436da829a83c32e7490b
Autor:
Shu-Chen Lu, Michelle Chen, Larissa Atangan, Elizabeth A. Killion, Renee Komorowski, Yuan Cheng, Chawita Netirojjanakul, James R. Falsey, Marina Stolina, Denise Dwyer, Clarence Hale, Shanaka Stanislaus, Todd Hager, Veena A. Thomas, John M. Harrold, David J. Lloyd, Murielle M. Véniant
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100263- (2021)
Summary: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) regulate glucose and energy homeostasis. Targeting both pathways with GIP receptor (GIPR) antagonist antibody (GIPR-Ab) and GLP-1 receptor (GLP-1R) agonis
Externí odkaz:
https://doaj.org/article/6fa1243f07684a9b91237d0446fb0986
Autor:
Marina Stolina, Xin Luo, Denise Dwyer, Chun-Ya Han, Rhonda Chen, Ying Zhang, YuMei Xiong, Yinhong Chen, Jun Yin, Artem Shkumatov, Brandon Ason, Clarence Hale, Murielle M Véniant
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0231234 (2020)
Cardiometabolic syndrome has become a global health issue. Heart failure is a common comorbidity of cardiometabolic syndrome. Successful drug development to prevent cardiometabolic syndrome and associated comorbidities requires preclinical models pre
Externí odkaz:
https://doaj.org/article/2a28d72dc487472ba9726d8fb014b07f
Autor:
Artem Shkumatov, Hong Zhou, Chi-Ming Li, Chun-Ya Han, Jun Yin, Denise Dwyer, Xin Luo, Brandon Ason, Marina Stolina, Karen Snyder, Tracy M. Yamawaki, Oliver Homann, Hongfei Ge
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Heart failure with reduced ejection fraction (HFrEF) constitutes 50% of HF hospitalizations and is characterized by high rates of mortality. To explore the underlying mechanisms of HFrEF etiology and progression, we studied the molecular and cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f67e1f055d2b750e1cff2660fc1ebeb
https://doi.org/10.1038/s41598-021-91214-2
https://doi.org/10.1038/s41598-021-91214-2
Autor:
Elizabeth A. Killion, Yuan Cheng, John M. Harrold, Veena A. Thomas, Shu-Chen Lu, James R. Falsey, Chawita Netirojjanakul, David Lloyd, Clarence Hale, Todd Hager, Shanaka Stanislaus, Marina Stolina, Renee Komorowski, Larissa Atangan, Murielle M. Véniant, Denise Dwyer, Michelle Chen
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 5, Pp 100263-(2021)
Cell Reports Medicine, Vol 2, Iss 5, Pp 100263-(2021)
Summary Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) regulate glucose and energy homeostasis. Targeting both pathways with GIP receptor (GIPR) antagonist antibody (GIPR-Ab) and GLP-1 receptor (GLP-1R) agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ac5166f5323cefa07e391f43ee52d4
https://pubmed.ncbi.nlm.nih.gov/34095885
https://pubmed.ncbi.nlm.nih.gov/34095885
Autor:
Denise Dwyer, Ying Zhang, Xin Luo, Jun Yin, Brandon Ason, Yumei Xiong, Murielle M. Véniant, Marina Stolina, Chun-Ya Han, Clarence Hale, Yinhong Chen, Rhonda Chen
Cardiometabolic syndrome has become a global health issue. Heart failure is a common comorbidity of cardiometabolic syndrome. Successful drug development to prevent cardiometabolic syndrome and associated comorbidities requires preclinical models pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d761dd6b13f74124f02d86420dc6b7
Autor:
Alison Wolfreys, Marina Stolina, Aimee M. Deaton, Sheetal V. Kumar, Jun Yin, Gabrielle Boyd, James R. Turk, Charles Glaus, Emily M. de Koning, Lucas D. Ward, Aurore Varela, Yusheng Qu, Gill Holdsworth, Jean-Guy Bienvenu, Yudong D. He, Martin Guillot, Melanie Felx, Denise Dwyer, Michael J. Engwall, Rogely W. Boyce, Kathrin Locher
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 115
Romosozumab (EVENITY™ [romosozumab-aqqg in the US]) is a humanized monoclonal antibody that inhibits sclerostin and has been approved in several countries for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Sclerosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869719aab28883f3928edc99a9d7aba0
https://pubmed.ncbi.nlm.nih.gov/32590049
https://pubmed.ncbi.nlm.nih.gov/32590049
Autor:
Denise Dwyer, Rogely Waite Boyce, Tara Aghaloo, Olga Bezouglaia, Flavia Q. Pirih, Danny Hadaya, Sotirios Tetradis, Akrivoula Soundia, Ioannis Gkouveris, Sarah M. Dry, Marina Stolina
Publikováno v:
Journal of Bone and Mineral Research. 34:171-181
Antiresorptive agents, such as bisphosphonates and denosumab, are frequently used for the management of osteoporosis. Indeed, both medications decrease the risk of osteoporotic fractures; however, these medications are associated with rare but potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac8261ff0716006dfb69ac94483d1dc
https://doi.org/10.1002/jbmr.3581
https://doi.org/10.1002/jbmr.3581
Autor:
William G. Richards, Denise Dwyer, Michael S. Ominsky, Kelly S. Villasenor, Qing-Tian Niu, Xiaodong Li, Marina Stolina, Mario Grisanti, Shawn T. Alexander, Frank Asuncion, James E. Tomlinson, Kelly Hensley, Hua Zhu Ke, Longchuan Yu, Chun-Ya Han, Charles W. Dean
Publikováno v:
Bone. 105:163-172
Sustained elevation of parathyroid hormone (PTH) is catabolic to cortical bone, as evidenced by deterioration in bone structure (cortical porosity), and is a major factor for increased fracture risk in chronic kidney disease (CKD). Etelcalcetide (AMG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44f25f67c199707b65f01f2c5b95a43
https://doi.org/10.1016/j.bone.2017.08.026
https://doi.org/10.1016/j.bone.2017.08.026
Autor:
M. Van Vliet, J.M. Spatz, Alison M Cloutier, Mary L. Bouxsein, H.Z. Ke, R. Ellman, Marina Stolina, Leeann Louis, Denise Dwyer
Publikováno v:
Life Sciences in Space Research. 12:32-38
Whereas much is known regarding the musculoskeletal responses to full unloading, little is known about the physiological effects and response to pharmacological agents in partial unloading (e.g. Moon and Mars) environments. To address this, we used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af42a5ff14f0f020393e6cf2852a4b8
https://doi.org/10.1016/j.lssr.2017.01.001
https://doi.org/10.1016/j.lssr.2017.01.001