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pro vyhledávání: '"Denise Dos Santos Smith"'
Autor:
Mateja Klika, Škopić, Denise, Dos Santos Smith, Anne, Gohla, Verena B K, Kunig, Andreas, Brunschweiger
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2541
Libraries of DNA-encoded compounds (DELs) are a validated screening technology for drug discovery. Here we describe a library synthesis strategy that starts with a solid phase-bound, chemically very stable hexathymidine DNA sequence "hexT." Different
TEAD-YAP Interaction Inhibitors and MDM2 Binders from DNA-Encoded Indole-Focused Ugi Peptidomimetics
Autor:
Marco Potowski, Alexander Dömling, Mateja Klika Škopić, Blaž Andlovic, Shabnam Shaabani, Roland Fried, Mohammad Akbarzadeh, Matthew Groves, Denise Dos Santos Smith, Hélène Adihou, Constantinos G. Neochoritis, Hacer Karatas, Andreas Brunschweiger, Tryfon Zarganes-Tzitzikas, Ran Zhang, Christian Ottmann, Verena B. K. Kunig, Stéphanie M. Guéret, Lukas Arendt, Jörg Rahnenführer, Ina Dormuth
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie-International Edition, 59(46), 20338-20342. Wiley
Angewandte Chemie (International ed. in English), 59(46), 20338-20342. WILEY-V C H VERLAG GMBH
Angewandte Chemie, 132(46), 20518-20522. Wiley-VCH Verlag
Angewandte Chemie International Edition
Angewandte Chemie-International Edition, 59(46), 20338-20342. Wiley
Angewandte Chemie (International ed. in English), 59(46), 20338-20342. WILEY-V C H VERLAG GMBH
Angewandte Chemie, 132(46), 20518-20522. Wiley-VCH Verlag
Angewandte Chemie International Edition
DNA-encoded combinatorial synthesis provides efficient and dense coverage of chemical space around privileged molecular structures. The indole side chain of tryptophan plays a prominent role in key, or ���hot spot���, regions of protein
Autor:
Mateja Klika Škopić, Denise dos Santos Smith, Anne Gohla, Verena B. K. Kunig, Andreas Brunschweiger
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625446
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b563fe3644e1c26d484c49530bd62ff
https://doi.org/10.1007/978-1-0716-2545-3_14
https://doi.org/10.1007/978-1-0716-2545-3_14