Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression.

Autor: Diossy M; Danish Cancer Institute, Copenhagen, Denmark.; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Tisza V; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Li H; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Sahgal P; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; The Eli and Edythe L. Broad Institute, Cambridge, MA, USA., Zhou J; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Sztupinszki Z; Danish Cancer Institute, Copenhagen, Denmark.; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Young D; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Nousome D; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Kuo C; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Jiang J; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Chen Y; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Ebner R; CytoTest Inc., Rockville, MD, USA., Sesterhenn IA; Joint Pathology Center, Silver Spring, MD, USA., Moncur JT; Joint Pathology Center, Silver Spring, MD, USA., Chesnut GT; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Petrovics G; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA., Klus GT; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Valcz G; MTA-SE Molecular Medicine Research Group, Hungarian Academy of Sciences, Budapest, 1051, Hungary., Nuzzo PV; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Ribli D; Department of Physics of Complex Systems, Eötvös Loránd University, Budapest, Hungary., Börcsök J; Danish Cancer Institute, Copenhagen, Denmark., Prosz A; Danish Cancer Institute, Copenhagen, Denmark., Krzystanek M; Danish Cancer Institute, Copenhagen, Denmark., Ried T; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Szuts D; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Rizwan K; Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Kaochar S; Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Pathania S; Center for Personalized Cancer Therapy, University of Massachusetts, Boston, MA, USA.; Department of Biology, University of Massachusetts, Boston, MA, USA., D'Andrea AD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA., Csabai I; Department of Physics of Complex Systems, Eötvös Loránd University, Budapest, Hungary., Srivastava S; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Biochemistry and Molecular & Cell Biology, Georgetown University School of Medicine, Washington, DC, USA., Freedman ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. freedman@broadinstitute.org.; The Eli and Edythe L. Broad Institute, Cambridge, MA, USA. freedman@broadinstitute.org.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. freedman@broadinstitute.org., Dobi A; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. adobi@cpdr.org.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA. adobi@cpdr.org., Spisak S; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary. Spisak.sandor@ttk.hu., Szallasi Z; Danish Cancer Institute, Copenhagen, Denmark. Zoltan.Szallasi@childrens.harvard.edu.; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Zoltan.Szallasi@childrens.harvard.edu.; 2nd Department of Pathology and Department of Bioinformatics, Semmelweis University, Budapest, Hungary. Zoltan.Szallasi@childrens.harvard.edu.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2024 Sep 19; Vol. 8 (1), pp. 208. Date of Electronic Publication: 2024 Sep 19.

A selective CutMix approach improves generalizability of deep learning-based grading and risk assessment of prostate cancer.

Autor: Patkar S; Artificial Intelligence Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Harmon S; Artificial Intelligence Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Sesterhenn I; The Joint Pathology Center, Silver Spring, MD 20910, USA., Lis R; Artificial Intelligence Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Merino M; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Young D; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Brown GT; Artificial Intelligence Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Greenfield KM; The Joint Pathology Center, Silver Spring, MD 20910, USA., McGeeney JD; The Joint Pathology Center, Silver Spring, MD 20910, USA., Elsamanoudi S; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Tan SH; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Schafer C; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Jiang J; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Petrovics G; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Dobi A; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Rentas FJ; The Joint Pathology Center, Silver Spring, MD 20910, USA., Pinto PA; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Chesnut GT; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.; F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Urology Service, Walter Reed National Military Medical Center, Bethesda, MD 20814, USA., Choyke P; Artificial Intelligence Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Turkbey B; Artificial Intelligence Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Moncur JT; The Joint Pathology Center, Silver Spring, MD 20910, USA.

Publikováno v: Journal of pathology informatics [J Pathol Inform] 2024 May 07; Vol. 15, pp. 100381. Date of Electronic Publication: 2024 May 07 (Print Publication: 2024).

Building resilience among families supporting relatives with ABI in rural NSW: testing the feasibility of telephone delivery of Strength2Strength program.

Autor: Young D; Mid Western Brain Injury Rehabilitation Program, Bathurst Health Service, Bathurst, Australia., Weaver J; Inpatient Mental Health Unit, Bathurst Health Service, Bathurst, Australia., Christie L; Allied Health Research Unit, St Vincent's Health Network, Sydney, Australia.; Nursing Research Institute, St Vincent's Health Network, St Vincent's Hospital Melbourne and Australian Catholic University, Sydney, Australia.; Brain Injury Rehabilitation Research Group, Ingham Institute for Applied Medical Research, Sydney, Australia., Genders M; Brain Injury Rehabilitation Research Group, Ingham Institute for Applied Medical Research, Sydney, Australia., Simpson GK; Brain Injury Rehabilitation Research Group, Ingham Institute for Applied Medical Research, Sydney, Australia.; John Walsh Centre for Rehabilitation Research, University of Sydney, Sydney, Australia.

Publikováno v: Brain injury [Brain Inj] 2024 Jan 28; Vol. 38 (2), pp. 84-98. Date of Electronic Publication: 2024 Feb 08.

Neonatal Intensive Care Unit Mixed Lipid Emulsion Use Associated With Reduced Cholestasis at Discharge in Surgical Patients.

Autor: Kulpins D; Case Western Reserve University School of Medicine, Cleveland, Ohio., Pickney C; Case Western Reserve University School of Medicine, Cleveland, Ohio., Garb M; Case Western Reserve University School of Medicine, Cleveland, Ohio., Dickson TF; MetroHealth, Internal Medicine and Pediatrics, Cleveland, Ohio., Young D; University Hospitals Cleveland Medical Center/UH Rainbow Babies and Children's Hospital, Pediatric Gastroenterology, Hepatology, and Nutrition, Cleveland, Ohio., Patrinos ME; University Hospitals Cleveland Medical Center/UH Rainbow Babies and Children's Hospital, Neonatology and Perinatal Medicine, Cleveland, Ohio., Patil N; University Hospitals Cleveland Medical Center, Clinical Research Center, Cleveland, Ohio., Miyasaka E; University Hospitals Cleveland Medical Center/UH Rainbow Babies and Children's Hospital, Pediatric Surgery, Cleveland, Ohio. Electronic address: eiichi.miyasaka@uhhospitals.org.

Publikováno v: The Journal of surgical research [J Surg Res] 2023 Jul; Vol. 287, pp. 1-7. Date of Electronic Publication: 2023 Feb 22.

Germline mutation landscape of DNA damage repair genes in African Americans with prostate cancer highlights potentially targetable RAD genes.

Autor: Kohaar I; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA. ikohaar@cpdr.org.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA. ikohaar@cpdr.org., Zhang X; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Tan SH; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA., Nousome D; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA., Babcock K; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA., Ravindranath L; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA., Sukumar G; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Mcgrath-Martinez E; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Rosenberger J; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Alba C; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Ali A; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA.; Urology Service, Walter Reed National Military Medical Center, Bethesda, MD, 20814, USA., Young D; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA., Chen Y; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA., Cullen J; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA., Rosner IL; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA., Sesterhenn IA; Joint Pathology Center, Silver Spring, MD, 20906, USA., Dobi A; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA., Chesnut G; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Urology Service, Walter Reed National Military Medical Center, Bethesda, MD, 20814, USA., Turner C; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Dalgard C; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Wilkerson MD; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Pollard HB; The American Genome Center, Precision Medicine Initiative for Military Medical Education and Research (PRIMER), Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Srivastava S; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA.; Department of Biochemistry and Molecular & Cell biology, Georgetown University School of Medicine, Washington, DC, 20057, USA., Petrovics G; Center for Prostate Disease Research, John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, MD, 20817, USA. gpetrovics@cpdr.org.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA. gpetrovics@cpdr.org.

Publikováno v: Nature communications [Nat Commun] 2022 Mar 15; Vol. 13 (1), pp. 1361. Date of Electronic Publication: 2022 Mar 15.