Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Denise D McKinley"'
Publikováno v:
British Journal of Pharmacology. 115:539-545
1. We examined how gamma-aminobutyric acid (GABA) influences interaction of picrotoxin and tert-butylbicyclophosphorothionate (TBPS) with recombinant rat alpha 1 beta 2 gamma 2 GABAA receptors stably expressed in human embryonic kidney cells (HEK293)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61749bc6cd68570437273eed1f13e92
https://doi.org/10.1111/j.1476-5381.1995.tb16368.x
https://doi.org/10.1111/j.1476-5381.1995.tb16368.x
Publikováno v:
British Journal of Pharmacology. 114:1040-1044
1. We examined the effects of methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM), a beta-carboline inverse agonist for the benzodiazepine site, on gamma-aminobutyric acid (GABA)-induced Cl-currents in several cloned rat GABAA receptor s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845b53878e50934ed45e92ac3bb68f3b
https://doi.org/10.1111/j.1476-5381.1995.tb13310.x
https://doi.org/10.1111/j.1476-5381.1995.tb13310.x
Autor:
Christopher W. Benjamin, Laura R. Fitzgerald, Kathleen A. Schellin, Jerry Slightom, Steven L. Roberds, Alla M. Karnovsky, Denise D. McKinley, Julie L. Piechan, Cara L. Ruble, Cynthia J. Mills, Lisa F. Gotow
Publikováno v:
Gene. 319
The ligand-gated ion channel family includes receptors for serotonin (5-hydroxytryptamine, 5-HT), acetylcholine, GABA, and glutamate. Drugs targeting subtypes of these receptors have proven useful for the treatment of various neuropsychiatric and neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f433f69e24c1f85472675698d54a2bd
https://pubmed.ncbi.nlm.nih.gov/14597179
https://pubmed.ncbi.nlm.nih.gov/14597179
Autor:
Royal J. Weaver, Timothy P. Boyle, Nancy C. Stratman, Donald B. Carter, Susan L. Kuiper, Denise D. McKinley, Mark E. Gurney, Edwige Dunn, Jennifer A. Boller, Jo A. Oostveen
Publikováno v:
Annals of neurology. 50(4)
The human apolipoprotein E4 (ApoE4) isoform is associated with genetic risk for Alzheimer's disease. To assess the effects of different ApoE isoforms on amyloid plaque formation, human ApoE3 and ApoE4 were expressed in the brains of transgenic mice u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f2006935d1eecbe5e2cd97890049be
https://pubmed.ncbi.nlm.nih.gov/11601499
https://pubmed.ncbi.nlm.nih.gov/11601499
Autor:
Denise D McKinley, Adele M. Pauley, Carol S Himes, Nancy C. Stratman, Alfredo G. Tomasselli, Brenda R Ellerbrook, Edwige Dunn, Donald B. Carter, Jeffrey S. Nye, Timothy J. Fleck, Riqiang Yan, Xiangdong Zhou
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 3, Iss 1, p 6 (2008)
Molecular Neurodegeneration, Vol 3, Iss 1, p 6 (2008)
Presenilin (PS1 or PS2) is an essential component of the active γ-secretase complex that liberates the Aβ peptides from amyloid precursor protein (APP). PS1 is regarded as an atypical aspartyl protease harboring two essential aspartic acids in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fe3bbbf9ccd91d6ef4d268448809bf