Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Denise Bounous"'
Autor:
William Siska, Ara Gupta, Denise Bounous, Holly Jordan, Laura Boone, Allison Vitsky, Adeyemi O Adedeji, Michael R. Logan, Adam D. Aulbach, Laura Cregar, Tara Arndt, Anne Provencher, Niraj Tripathi, Lila Ramaiah
Publikováno v:
Veterinary Clinical Pathology. 48:383-388
The interpretation of clinical pathology results from nonclinical safety studies is a fundamental component in hazard identification of new drug candidates. The ever-increasing complexity of nonclinical safety studies and sophistication of modern ana
Autor:
Ara Gupta, Tara Arndt, Michael R. Logan, Adam D. Aulbach, Anne Provencher, Lila Ramaiah, Laura Boone, Holly Jordan, William Siska, Denise Bounous, Allison Vitsky, Adeyemi O Adedeji, Niraj Tripathi, Laura Cregar
Publikováno v:
Veterinary Clinical Pathology. 48:389-399
Clinical pathology reporting practices are diverse among individuals and organizations involved in nonclinical toxicology studies. Clear, informative, and consistent reporting of clinical pathology results increases their value and avoids misinterpre
Autor:
James Hennan, Michael Gill, John R. Megill, Marc H. Davies, Shawn P. Clark, Michael J. Graziano, Denise Bounous, Randy White, Kristen Horn, Evan B. Janovitz, Thomas P. Sanderson
Publikováno v:
Toxicological Sciences. 155:348-362
BMS-986094, a 2'-C-methylguanosine prodrug that was in development for treatment of chronic hepatitis C infection was withdrawn from Phase 2 clinical trials because of unexpected cardiac and renal adverse events. Investigative nonclinical studies wer
Autor:
Lila Ramaiah, Daniela Ennulat, Denise Bounous, Lindsay Tomlinson, Allison Vitsky, Niraj Tripathi, Valerie G. Barlow, Florence Poitout-Belissent
Publikováno v:
Toxicologic Pathology. 44:163-172
The Society of Toxicologic Pathology formed a working group in collaboration with the American Society for Veterinary Clinical Pathology to provide recommendations for the appropriate inclusion of clinical pathology evaluation in recovery arms of non
Autor:
Cindy X. Zhang, Danielle Greenawalt, Ke Xu, Julie Panzica-Kelly, Richard A. Westhouse, Ronald Fleming, Ashvinikumar V. Gavai, Jennifer Price, Denise Bounous, Shodeinde Coker, Karen Augustine-Rauch, Kezi Unsal-Kacmaz
Publikováno v:
Cancer Research. 80:1742-1742
Bromodomain and extraterminal (BET) proteins recognize acetylated lysine residues for the purpose of transcriptional regulation of genes, including those involved in stem cell renewal and oncogenes such as MYC. Inhibition of BET proteins BRD2, BRD3,
Autor:
Evan B. Janovitz, Lisa Berman-Booty, Glenn H. Cantor, Rukiye Eraslan, Beverly K. Jones, Michael Hayward, Denise Bounous, Umesh Hanumegowda, Olesia Buiakova, Susan Wee
Publikováno v:
Veterinary pathology. 55(2)
C-terminal Src kinase (Csk) is one of the critical negative regulators of the Src family of kinases. The Src family of kinases are nonreceptor tyrosine kinases that regulate inflammation, cell proliferation, motility, and adhesion. To investigate pot
The hematopoietic system is responsible for the continuous production of highly specialized mature circulating blood cells. Due to its high metabolic and proliferative rate, and because the functions performed by blood cells are vital to an organism,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4380d5af4ac91019432349db17ffd3f3
https://doi.org/10.1016/b978-0-12-809841-7.00013-7
https://doi.org/10.1016/b978-0-12-809841-7.00013-7
Autor:
Denise Bounous, Ernie Harpur
Publikováno v:
The Clinical Chemistry of Laboratory Animals ISBN: 9781315155807
The Clinical Chemistry of Laboratory Animals
The Clinical Chemistry of Laboratory Animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::013a97bcdff345a7961ad199e8e55f45
https://doi.org/10.1201/9781315155807-12
https://doi.org/10.1201/9781315155807-12
Autor:
Janet DiPiero, Glen B. Banks, Leslie K. Jacobsen, Nino Devidze, Denise Bounous, Linda J. Bristow, Stephen A. Stimpson, Sean C. Little, Michael K. Ahlijanian, Robert C. Gagnon, Courtney M. Smith, Mark J. Majchrzak, Alan S. Robertson, Fizal Nabbie
Publikováno v:
Neuromuscular disorders : NMD. 27(7)
Enzyme-linked and electrochemiluminescence immunoassays were developed for quantification of amino (N-) terminal fragments of the skeletal muscle protein titin (N-ter titin) and qualified for use in detection of urinary N-ter titin excretion. Urine f
Autor:
Nancy E. Everds, David Zelmanovic, Niraj Tripathi, Thomas C. Register, Shashi K. Ramaiah, Debra Wescott, Anne Provencher Bolliger, Holly L. Jordan, Florence Poitout, Denise Bounous
Publikováno v:
Toxicologic Pathology. 42:1058-1068
Most published reviews of preclinical toxicological clinical pathology focus on the fundamental aspects of hematology, clinical chemistry, coagulation, and urinalysis in routine toxicology animal species, for example, rats, mice, dogs, and nonhuman p