Výsledky vyhledávání - "Denise Belgorosky"

Akademický článek

Synthesis of new para-aminobenzoic acid derivatives, in vitro biological evaluation and preclinical validation of DAB-2-28 as a therapeutic option for the treatment of bladder cancer

Autor: Yassine Oufqir, Laurie Fortin, Julie Girouard, Francis Cloutier, Maude Cloutier, Marie-France Leclerc, Denise Belgorosky, Ana María Eiján, Gervais Bérubé, Carlos Reyes-Moreno

Publikováno v: European Journal of Medicinal Chemistry Reports, Vol 6, Iss , Pp 100069- (2022)

Chronic inflammation plays a crucial role in bladder cancer (BCa) development and progression. To offer a unique treatment opportunity for this type of cancer, a hydrazide derivative namely, DAB-1, was recently identified in our laboratory as a poten

Externí odkaz: https://doaj.org/article/7c24b9d922da41028e43e066f7c5efdf

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Akademický článek

Ephrin-B1 Is a Novel Biomarker of Bladder Cancer Aggressiveness. Studies in Murine Models and in Human Samples

Autor: María Victoria Mencucci, Lara Lapyckyj, Marina Rosso, María José Besso, Denise Belgorosky, Mariana Isola, Silvia Vanzulli, Catalina Lodillinsky, Ana María Eiján, Juan Carlos Tejerizo, Matías Ignacio Gonzalez, María Ercilia Zubieta, Mónica Hebe Vazquez-Levin

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Bladder cancer (BC) is the ninth most common cancer worldwide, but molecular changes are still under study. During tumor progression, Epithelial cadherin (E-cadherin) expression is altered and β-catenin may be translocated to the nucleus, where it a

Externí odkaz: https://doaj.org/article/774b48528ee84a9fbc707bec38a4eaf8

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Microfluidic devices to analyze the response of sphere-forming stem-like populations to chemotherapeutic drugs

Autor: Eduardo Imanol Agüero, Denise Belgorosky, Julio Israel García-Silva, Ross Booth, Betiana Lerner, Maximiliano Sebastián Pérez, Ana María Eiján

Microfluidic platforms for clinical use are a promising translational strategy for cancer research specially for drug screening. Identifyng Cancer Stem Cells (CSC) using sphere culture techniques in microfluidic devices (MDs) showed to be better repr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5c4889f9f837c664db82ede69eb8fe0
https://doi.org/10.21203/rs.3.rs-2464538/v1

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Effect of nitric oxide inhibition in Bacillus Calmette-Guerin bladder cancer treatment

Autor: Natalia Patricia Balarino, Eduardo Omar Sandes, Pablo Damian Cresta Morgado, Denise Belgorosky, Catalina Lodillinsky, Lina Marino, Yanina Verónica Langle, Erica Rojas Bilbao, Ana María Eiján, Macarena Zambrano

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Background: Bacillus Calmette-Guerin (BCG) is the standard treatment for patients with high-risk non-muscle invasive bladder cancer (BC). Despite its success, about 30–50% of patients are refractory. It was reported that inducible nitric oxide synt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663e06f4f310e8d2f773f1f8583a8f9d
https://doi.org/10.1016/j.niox.2020.03.003

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Inhibition of breast tumor growth by N(G)-nitro-l-arginine methyl ester (l-NAME) is accompanied by activation of fibroblasts

Autor: José Ignacio Gómez Escalante, Marianela Sciacca, Macarena Zambrano, Yanina Verónica Langle, Catalina Lodillinsky, Eduardo Omar Sandes, Fernanda Roca, Denise Belgorosky, Ana María Eiján

Publikováno v: Nitric Oxide. 93:34-43

Nitric Oxide (NO) is involved in many physiological and pathological processes. It is generated by a family of NO synthases (NOS), being the inducible isoform, iNOS, responsible for higher amounts of NO. Here, we report that pharmacological inhibitio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9653f86b170fabce8b60634a0bb1c7cd
https://doi.org/10.1016/j.niox.2019.09.008

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TMET-26. PRIMARY OLIGODENDROGLIOMA CELL CULTURE VIABILITY: AN IN VITRO STUDY WITH METABOLIC MODULATORS

Autor: Marcela Villaverde, Elsa Hincapié Arias, Martin Merenzon, Alejandro Mazzon, Eduardo Seoane, Denise Belgorosky, Ana Maria Eiján

Publikováno v: Neuro-Oncology. 24:vii267-vii267

Oligodendrogliomas are tumors that develop from oligodendrocytes, the myelinating cells of the central nervous system. Oligodendrocytes are highly metabolically active cells that synthesize and transfer metabolites to neighboring cells. Given its int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca193d1964a5809f0295b7c8ecb34a0e
https://doi.org/10.1093/neuonc/noac209.1031

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Relevance of iNOS expression in tumor growth and maintenance of cancer stem cells in a bladder cancer model

Autor: Jovane Hamelin-Morrissete, Lina Marino, Yanina Verónica Langle, Julie Girouard, Denise Belgorosky, Carlos Reyes-Moreno, H. Malagrino, Ana María Eiján, Eduardo Imanol Agüero

The expression of inducible nitric oxide (NO) synthase (iNOS) in human bladder cancer (BC) is a poor prognostic factor associated with invasion and tumor recurrence. Here, we evaluated the relevance of iNOS expression in BC progression and in cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32bb6ddb76034284c273c7681ee58218
https://link.springer.com/article/10.1007/s00109-020-01973-0

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Ephrin-B1 Is a Novel Biomarker of Bladder Cancer Aggressiveness. Studies in Murine Models and in Human Samples

Autor: Mónica H. Vazquez-Levin, Denise Belgorosky, Marina Rosso, Juan Carlos Tejerizo, Silvia Vanzulli, Maria Ercilia Zubieta, Mariana Isola, Matías Ignacio González, Ana María Eiján, María Victoria Mencucci, María José Besso, Catalina Lodillinsky, Lara Lapyckyj

Publikováno v: Frontiers in Oncology, Vol 10 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Oncology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132644dcc9d8c60c01ed14907f5a699e
https://www.frontiersin.org/article/10.3389/fonc.2020.00283/full

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Abstract 3091: Relevance of iNOS expression in bladder cancer stem cells

Autor: H. Malagrino, Ana María Eiján, Jovane Hamelin-Morrissette, Denise Belgorosky, Julie Girouard, Yanina Verónica Langle, Lina Marino, Carlos Reyes-Moreno, Eduardo I. Agüero

Publikováno v: Cancer Research. 81:3091-3091

Background: Bladder cancer (BC) is one of the most common tumors of the male urogenital tract and an important worldwide cause of death. Increasing evidence has indicated the presence of cancer stem cells (CSCs) in many types of tumors, associated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::930cb6a14f1e27f2c652bc08b94fac42
https://doi.org/10.1158/1538-7445.am2021-3091

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Abstract 362: Patients with cervical cancer display an increase in leukocytes and myeloid cells that express S100A9

Autor: Pablo Damian Cresta Morgado, M Ostojich, Andrea Aguilar, Denise Belgorosky, Valeria Caceres, Pablo Menendez, Ana María Eiján, Yanina Verónica Langle, Laura Lay, Eduardo Omar Sandes, Pablo M. Marenco

Publikováno v: Cancer Research. 81:362-362

Cervical cancer is the second most common type of cancer affecting women worldwide. Leukocytosis have been related with treatment failure in this pathology, associated with the induction and accumulation of myeloid derived suppressor cells (MDSC) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd4cf86549bd568301884e288e691eff
https://doi.org/10.1158/1538-7445.am2021-362

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