Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Denise A. Nachowiak"'
Publikováno v:
Journal of the American College of Cardiology. 19(5):1085-1090
Although initially developed to reduce the risk of bleeding, second-generation (clot-selective) thrombolytic agents have been found to induce more prompt and frequent recanalizatton than do nonselective, first-generation agents. To determine whether
Publikováno v:
Circulation. 81:1362-1373
We have previously explored induction of coronary thrombolysis with tissue-type plasminogen activator (t-PA) administered intramuscularly. Absorption-enhancing agents that rendered the approach feasible were identified, but large amounts of activator
Autor:
John A. Delyani, Ellen G. Mcmahon, Eric A.G. Blomme, Denise A. Nachowiak, Beverly K. Kekec, Ricardo Rocha, Gregory E. Frierdich, Amy E. Rudolph
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 283(5)
Vascular inflammation was examined as a potential mechanism of aldosterone-mediated myocardial injury in uninephrectomized rats receiving 1% NaCl-0.3% KCl to drink for 1, 2, or 4 wk and 1) vehicle, 2) aldosterone infusion (0.75 μg/h), or 3) aldoster
Publikováno v:
Circulation. 77(4)
Biochemical modification of tissue-type plasminogen activator (t-PA) designed to alter pharmacokinetics and pharmacodynamics offers promise for development of pharmaceuticals particularly suitable for treatment of specific disorders and for induction