Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Denise A. Gordon"'
Autor:
Adam D. Biales, David C. Bencic, Robert W. Flick, Armah Delacruz, Denise A. Gordon, Weichun Huang
Publikováno v:
Toxicon: X, Vol 8, Iss , Pp 100060- (2020)
The canonical mode of action (MOA) of microcystins (MC) is the inhibition of protein phosphatases, but complete characterization of toxicity pathways is lacking. The existence of over 200 MC congeners complicates risk estimates worldwide. This work e
Externí odkaz:
https://doaj.org/article/96a9962492794a7480270cb9ffd7d768
Autor:
Angela L. Batt, James M. Lazorchak, Mitchell S. Kostich, Robert W. Flick, Mary J. See, David C. Bencic, Adam D. Biales, Denise A. Gordon
Publikováno v:
Environ Toxicol Chem
We describe initial development of microarray-based assays for detecting 4 pyrethroid pesticides (bifenthrin, cypermethrin, esfenvalerate, and permethrin) in water. To facilitate comparison of transcriptional responses with gross apical responses, we
Autor:
Armah Delacruz, David C. Bencic, Denise A. Gordon, Weichun Huang, Adam D. Biales, Robert W. Flick
Publikováno v:
Toxicon: X
Toxicon: X, Vol 8, Iss, Pp 100060-(2020)
Toxicon: X, Vol 8, Iss, Pp 100060-(2020)
The canonical mode of action (MOA) of microcystins (MC) is the inhibition of protein phosphatases, but complete characterization of toxicity pathways is lacking. The existence of over 200 MC congeners complicates risk estimates worldwide. This work e
Autor:
Kristen Keteles, Denise A. Gordon, Adam D. Biales, James M. Lazorchak, Elizabeth C. Punska, Dana L. Winkelman, Kasie M. Auger, Kathleen F. Arcaro, David L. Lattier, Aaron Jastrow
Publikováno v:
Environmental Toxicology and Chemistry. 36:3102-3107
The egg yolk precursor protein vitellogenin is widely used as a biomarker of estrogen exposure in male fish. However, standardized methodology is lacking and little is known regarding the reproducibility of results among laboratories using different
Autor:
David C. Bencic, Robert W. Flick, Mitchell S. Kostich, Mary J. See, Adam D. Biales, Denise A. Gordon, Angela L. Batt, James M. Lazorchak
Publikováno v:
Aquatic Toxicology. 179:27-35
Omics technologies have long since promised to address a number of long standing issues related to environmental regulation. Despite considerable resource investment, there are few examples where these tools have been adopted by the regulatory commun
Autor:
David A. Agard, Melissa C. Wratschko, James M. Lazorchak, Mark E. Smith, Lisa Holden, Denise A. Gordon, Steve Wilcox
Publikováno v:
Environmental Toxicology and Chemistry. 33:126-133
Fathead minnows are routinely cultured for use in aquatic toxicology studies. A new mass culture system described in the present study consisted of 6 stainless steel tanks, each containing 68 fish and 20 spawning substrates. Spawning results are comp
Publikováno v:
Environmental Toxicology and Chemistry. 20:1979-1985
We report the development of a quantifiable exposure indicator for measuring the presence of environmental estrogens in aquatic systems. Synthetic oligonucleotides, designed specifically for the vitellogenin gene (Vg) transcription product, were used
Autor:
Denise A. Gordon, Rodney D. Johnson, Philip M. Cook, David L. Lattier, Gary W. Holcombe, Suzanne A. Christ, Douglas Lothenbach, Joseph E. Tietge, Joseph D. Fernandez, Kathleen M. Jensen, Ann L. Linnum
Publikováno v:
Environmental Toxicology and Chemistry. 17:2408-2421
The toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the early life stages of F1 generation brook trout (Salvelinus fontinalis) was determined, when dosed by maternal transfer. Effects were compared across six treatments, including a cont
Autor:
Joni Torsella, Jerry O. Wolff, Richard N. Silbiger, M. Kate Smith, David L. Lattier, Denise A. Gordon
Publikováno v:
Journal of Mammalogy. 79:604-611
Genetic relatedness of gray-tailed voles ( Microtus canicaudus ) was determined by random amplified polymorphic DNA (RAPD). This work is the first reported use of the RAPD method for pedigree analysis of M. canicaudus and demonstrates the feasibility