Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Denise A. Contos"'
Autor:
Teresa R. Henry, John Weissmann, Peter Bryan, Paul Lehmann, Natalie L. South, Monica Lee Whitmire, Susan Ohorodnik, Denise A. Contos, John Schetter, David Reed, Troy Appleton, Chantal Robichaud
Publikováno v:
The AAPS Journal. 14:523-529
Nonclinical safety studies are required to follow applicable Good Laboratory Practice (GLP) regulations. Nonclinical dose formulations are required to be analyzed to confirm the analyte concentration, homogeneity, and stability. Analytical samples th
Autor:
Joseph E. Tomaszewski, Michael A. Hawk, Daphne Vasconcelos, Glenn D. Ritchie, Pramod S. Terse, Denise A. Contos, James O. Peggins, Jerry D. Johnson, Michael J. Ryan, Susan P. Perrine
Publikováno v:
Toxicologic pathology. 39(4)
ST-20 (sodium 2,2-dimethylbutyrate) is a potential therapeutic agent for treatment of β-thalassemia and sickle cell disease. A subchronic oral toxicity study was conducted in Sprague-Dawley rats (10/sex/dose) at gavage dosages of 0 (vehicle control)
Publikováno v:
Journal of Pharmaceutical Sciences. 80:768-771
This is a report of the pharmacokinetics of methyprylon and its major plasma metabolite, 5-methylpyrithyldione, in an overdosed patient using a reversed-phase HPLC assay. The decline in the concentration of plasma methyprylon was nonlinear between 66
Publikováno v:
Environmental Science & Technology. 22:908-915
The identification and quantification of hydroxylated nitro aromatic compounds in an ambient air particulate extract are presented here. The isomer substitution observed for these compounds supports the mechanism proposed from smog chamber studies: O