Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Denise, van Rossum"'
Autor:
Tommy Regen, Hana Janova, Anne Winkler, Nasrin Saiepour, Denise van Rossum, Christin Döring, Ulla Gertig, Uwe-Karsten Hanisch, Wolfgang Brück
Publikováno v:
Glia. 65:1176-1185
Microglia as principle innate immune cells of the central nervous system (CNS) are the first line of defense against invading pathogens. They are capable of sensing infections through diverse receptors, such as Toll-like receptor 4 (TLR4). This recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4db91f33a7b1f310495c1240cde5148
https://doi.org/10.1002/glia.23151
https://doi.org/10.1002/glia.23151
Publikováno v:
Microelectronic Engineering. 158:52-58
Cheap and disposable Point-of-Care diagnostic devices are of great interest to combat the rising cost of healthcare in industrial nations but also for a widespread use in the developing world. Paper based microfluidic devices as well as well-establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44ee58df40e2117aa229ec085ba36018
https://doi.org/10.1016/j.mee.2016.03.020
https://doi.org/10.1016/j.mee.2016.03.020
Autor:
Alexander Götz, Ulla Gertig, Tommy Regen, Josef Priller, Hannelore Ehrenreich, Hendrikus Boddeke, Christin Fritsche, Wolfgang Brück, Marco Prinz, Chotima Böttcher, Sandra Ribes, Christine Stadelmann, Simone Rolfes, Martin S. Weber, Denise van Rossum, Claudia Wrzos, Hana Janova, Inge R. Holtman, Konrad Gronke, Tobias Pukrop, Nasrin Saiepour, Bart J. L. Eggen, Gabriela Salinas-Riester, Jonathan R. Weinstein, Jens Kopatz, Anne-Sophie Ernst, Uwe-Karsten Hanisch
Publikováno v:
Glia. 64:635-649
Microglia, innate immune cells of the CNS, sense infection and damage through overlapping receptor sets. Toll-like receptor (TLR) 4 recognizes bacterial lipopolysaccharide (LPS) and multiple injury-associated factors. We show that its co-receptor CD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c80cb119f48ba305b1c31f3380101429
https://doi.org/10.1002/glia.22955
https://doi.org/10.1002/glia.22955
Autor:
Christiane Menzfeld, Alexander Götz, Peter Teismann, Denise Tischner, Tommy Regen, Wolfgang Brück, Thomas Herdegen, Martin S. Weber, Philippe Boutin, Sandra Ribes, Shlomo Rotshenker, Michael John, Vanessa Bremes, Angela Borisch, Tobias Pukrop, Jürgen Wienands, Konstantin Neumann, Roland Nau, Helmut Kettenmann, Vicky Waetzig, Fred Lühder, Uwe-Karsten Hanisch, Hana Janova, Iain R. Greig, Alexander Mildner, Denise van Rossum, Holger M. Reichardt, Jörg Scheffel, Michael Müller, Marco Prinz
Publikováno v:
Glia. 63:1083-1099
The putative protein tyrosine kinase (PTK) inhibitor tyrphostin AG126 has proven beneficial in various models of inflammatory disease. Yet molecular targets and cellular mechanisms remained enigmatic. We demonstrate here that AG126 treatment has bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ae829bc2f7b8151092d31202d6404a
https://doi.org/10.1002/glia.22803
https://doi.org/10.1002/glia.22803
Autor:
Christin, Döring, Tommy, Regen, Ulla, Gertig, Denise, van Rossum, Anne, Winkler, Nasrin, Saiepour, Wolfgang, Brück, Uwe-Karsten, Hanisch, Hana, Janova
Publikováno v:
Glia. 65(7)
Microglia as principle innate immune cells of the central nervous system (CNS) are the first line of defense against invading pathogens. They are capable of sensing infections through diverse receptors, such as Toll-like receptor 4 (TLR4). This recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63369702bf820612392138b35f6c300c
https://pubmed.ncbi.nlm.nih.gov/28471051
https://pubmed.ncbi.nlm.nih.gov/28471051
Autor:
Jan Walter, Denise van Rossum, Frank L. Heppner, Roland Goldbrunner, Arend Koch, Lutz Liebmann, Susanne A. Kuhn, Michael Brodhun, Linn L. Handel, Uwe-Karsten Hanisch
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 138:141-151
Patients with malignancies often suffer from thrombembolic events that complicate the course of cancer disease and reduce the patients' quality of life or shorten the survival time in severe cases. This phenomenon is also known for patients with prim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c6c2cbb9f0beec3e4de2dc592b134c
https://doi.org/10.1007/s00432-011-1078-x
https://doi.org/10.1007/s00432-011-1078-x
Autor:
Tommy Regen, Christine Stadelmann, Matthias Schulz, Han-Ning Chuang, Kathrin Bayanga, Tobias Pukrop, Laila Siam, Denise van Rossum, Uwe-Karsten Hanisch, Faramarz Dehghani, Florian Klemm, Stephan Heermann, Lorenz Trümper, Ingo Bechmann, Anja Hoffmann, Claudia Binder, Raphaela Lohaus
Publikováno v:
Glia. 58:1477-1489
Although there is increasing evidence that blood-derived macrophages support tumor progression, it is still unclear whether specialized resident macrophages, such as brain microglia, also play a prominent role in metastasis formation. Here, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ed9a5f01e1e97607c3b1c967a14a6c
https://doi.org/10.1002/glia.21022
https://doi.org/10.1002/glia.21022
Autor:
Denise van Rossum, Uwe-Karsten Hanisch
Publikováno v:
Metabolic Brain Disease. 19:393-411
Microglia--the macrophage equivalent of the CNS--safeguards and supports neuronal functions. Threats to the CNS homeostasis can trigger a rapid transformation of these cells from a normally "resting" into alerted and "activated" states. Microglia pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c98404a685120cd93926129b2d4c4cf
https://doi.org/10.1023/b:mebr.0000043984.73063.d8
https://doi.org/10.1023/b:mebr.0000043984.73063.d8
Autor:
Yiheng Xie, Helmut Kettenmann, Jari Koistinaho, Klaus Gast, Denise van Rossum, Rolf Misselwitz, Gundars Goldsteins, Seppo Auriola, Uwe-Karsten Hanisch, Thomas Möller
Publikováno v:
Journal of Biological Chemistry. 279:51880-51887
The serine protease thrombin is known as a blood coagulation factor. Through limited cleavage of proteinase-activated receptors it can also control growth and functions in various cell types, including neurons, astrocytes, and microglia (brain macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e983215f3d02088d52016331fa2364
https://doi.org/10.1074/jbc.m408318200
https://doi.org/10.1074/jbc.m408318200
Autor:
Christiane, Menzfeld, Michael, John, Denise, van Rossum, Tommy, Regen, Jörg, Scheffel, Hana, Janova, Alexander, Götz, Sandra, Ribes, Roland, Nau, Angela, Borisch, Philippe, Boutin, Konstantin, Neumann, Vanessa, Bremes, Jürgen, Wienands, Holger M, Reichardt, Fred, Lühder, Denise, Tischner, Vicky, Waetzig, Thomas, Herdegen, Peter, Teismann, Iain, Greig, Michael, Müller, Tobias, Pukrop, Alexander, Mildner, Helmut, Kettenmann, Wolfgang, Brück, Marco, Prinz, Shlomo, Rotshenker, Martin S, Weber, Uwe-Karsten, Hanisch
Publikováno v:
Glia. 63(6)
The putative protein tyrosine kinase (PTK) inhibitor tyrphostin AG126 has proven beneficial in various models of inflammatory disease. Yet molecular targets and cellular mechanisms remained enigmatic. We demonstrate here that AG126 treatment has bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5235718fb816095ed7b6251567b5267c
https://pubmed.ncbi.nlm.nih.gov/25731696
https://pubmed.ncbi.nlm.nih.gov/25731696