Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Denise, Sy"'
Autor:
David P. Kelly, Melanie Spotheim-Maurizot, Denise Sy, Chris Clark, Jonathan M. White, Pavel N. Lobachevsky, George R. Clark, Christopher J. Squire, Monica E. Reum, Sam Broadhurst, Roger F. Martin
12 pages of supplementary material (Materials and Methods, 3 tables, 3 figures, references)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c41de755fa09d10e49491e3658d37c3
https://doi.org/10.1158/0008-5472.22363523
https://doi.org/10.1158/0008-5472.22363523
Autor:
David P. Kelly, Melanie Spotheim-Maurizot, Denise Sy, Chris Clark, Jonathan M. White, Pavel N. Lobachevsky, George R. Clark, Christopher J. Squire, Monica E. Reum, Sam Broadhurst, Roger F. Martin
New analogues of the minor groove binding ligand Hoechst 33342 have been investigated in an attempt to improve radioprotective activity. The synthesis, DNA binding, and in vitro radioprotective properties of methylproamine, the most potent derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a751037758badc16f0de0f758d41369f
https://doi.org/10.1158/0008-5472.c.6493754.v1
https://doi.org/10.1158/0008-5472.c.6493754.v1
Publikováno v:
The Journal of Peptide Research. 61:47-57
Recently, it has been shown that mammalian PEBPs are implicated in several signalling pathways controlling the cellular cycle. In particular, during brain development, the N-terminal part of mammalian PEBP is specifically cleaved and the resulting 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba8e24f1b0e34a931e8ea53b0a0426ac
https://doi.org/10.1034/j.1399-3011.2003.21039.x
https://doi.org/10.1034/j.1399-3011.2003.21039.x
Autor:
Fabienne Godin, Denise Sy, Hélène Chautard, Béatrice Vallée, Françoise Vovelle, Hélène Bénédetti, Baptiste Legrand, Aurélie Gombault
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩
Journal of Molecular Biology, Elsevier, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩
Tfs1p and Ylr179cp are yeast proteins belonging to the PEBP family. Tfs1p, but not Ylr179cp, has been shown to interact with and inhibit Ira2p, a GTPase-activating protein of Ras. Tfs1p has been shown to be a specific inhibitor of the CPY protease an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011ad8f80df5f41521634c76deab30c1
https://doi.org/10.1016/j.jmb.2007.09.057
https://doi.org/10.1016/j.jmb.2007.09.057
Autor:
Nathalie Gillard, Bertrand Castaing, Melanie Spotheim-Maurizot, Marie Běgusová, Michel Charlier, Denise Sy
Publikováno v:
Radiation Physics and Chemistry. 72:265-270
We discuss here modifications of DNA and protein radiolysis due to the interaction of these two partners in specific complexes. Experimental patterns of frank strand breaks (FSB) and alkali revealed breaks (ARB) obtained for DNA lac operator bound to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65980be82f90664183762b11db31126c
https://doi.org/10.1016/j.radphyschem.2004.01.009
https://doi.org/10.1016/j.radphyschem.2004.01.009
Autor:
Roger F. Martin, Melanie Spotheim-Maurizot, David P. Kelly, Pavel Lobachevsky, George R. Clark, Monica E. Reum, Sam Broadhurst, Denise Sy, Jonathan M. White, Christopher J. Squire, Christopher M. Clark
Publikováno v:
Cancer Research. 64:1067-1070
New analogues of the minor groove binding ligand Hoechst 33342 have been investigated in an attempt to improve radioprotective activity. The synthesis, DNA binding, and in vitro radioprotective properties of methylproamine, the most potent derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcdbbbd216cba993fe57e936609b1572
https://doi.org/10.1158/0008-5472.can-03-2423
https://doi.org/10.1158/0008-5472.can-03-2423
Publikováno v:
Langmuir. 18:7309-7312
To probe the effect of charge and ligand polar head, we report on the interaction between a plant lipid transfer protein (LTP1) and cationic surfactants, anionic and nonionic polymer grafted lipids, cetyl trimethylammonium bromide (CTAB), dihexadecyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a4b030a814398fccd30741867c8a31
https://doi.org/10.1021/la020163w
https://doi.org/10.1021/la020163w
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 19:141-158
RADACK was conceived to simulate the radiation-induced attack to different DNA forms and complexes. It allows to separately calculate the probability of attack to each reactive atom of the sugar and of the base and takes into account the sequence-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a81283c29e26e9d1f45911a9a690c0e
https://doi.org/10.1080/07391102.2001.10506727
https://doi.org/10.1080/07391102.2001.10506727
Publikováno v:
Radiation Research. 156:110-117
Eon, S., Culard, F., Sy, D., Charlier, M. and Spotheim-Maurizot, M. Radiation Disrupts Protein-DNA Complexes through Damage to the Protein. The lac Repressor-Operator System. Radiat. Res. 156, 110-117 (2001). Binding of a protein to its cognate DNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6ea95a418c1b34e9d37799d82d3e60
https://doi.org/10.1667/0033-7587(2001)156[0110:rdpdct]2.0.co
https://doi.org/10.1667/0033-7587(2001)156[0110:rdpdct]2.0.co
Publikováno v:
Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta). 106:137-145
Among the DNA lesions induced by ionising radiation, one of the most abundant base modifications is that of guanine (G) into 8-oxo-7-hydro-2′-deoxyguanosine (oxoG). The Escherichia coli lac operator–lac repressor complex bearing one or several ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d397b2ebfe83a27456fe388706a077cc
https://doi.org/10.1007/s002140100253
https://doi.org/10.1007/s002140100253