Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Denise, Mattei"'
A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection
Autor:
Gigliola Zanghì, Shruthi S. Vembar, Sebastian Baumgarten, Shuai Ding, Julien Guizetti, Jessica M. Bryant, Denise Mattei, Anja T.R. Jensen, Laurent Rénia, Yun Shan Goh, Robert Sauerwein, Cornelus C. Hermsen, Jean-François Franetich, Mallaury Bordessoulles, Olivier Silvie, Valérie Soulard, Olivier Scatton, Patty Chen, Salah Mecheri, Dominique Mazier, Artur Scherf
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 2951-2963 (2018)
Summary: Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum during blood stage infection. Here, we use ChIP sequencing to demonstrate that sporozoites fr
Externí odkaz:
https://doaj.org/article/939c4b5bec404e3d98afcc5d3b2f4e81
Autor:
Adéla Nacer, Emeric Roux, Sébastien Pomel, Christine Scheidig-Benatar, Hiroshi Sakamoto, Frank Lafont, Artur Scherf, Denise Mattei
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29039 (2011)
BACKGROUND: The expression of the clonally variant virulence factor PfEMP1 mediates the sequestration of Plasmodium falciparum infected erythrocytes in the host vasculature and contributes to chronic infection. Non-cytoadherent parasites with a chrom
Externí odkaz:
https://doaj.org/article/91eb9b20d6804940b625d66cc4217545
Autor:
Denise Mattei, Artur Scherf
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 87, Pp 163-168 (1992)
We characterized the Plasmodium falciparum antigen 332 (Ag332) which is specifically expressed during the asexual intraerythrocytic cycle of the parasite. The corresponding Pf332 gene has been located in the subtelomeric region of chromosome 11. Furt
Externí odkaz:
https://doaj.org/article/cc200fa2c9684569807de4810d94852d
Autor:
Artur Scherf, Carolyn Petersen, Richard Carter, Pietro Alano, Rick Nelson, Masamichi Aikawa, Denise Mattei, Luiz Pereira da Silva, James Leech
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 87, Pp 91-94 (1992)
We identified a gametocyte-specific protein of Plasmodium falciparum called Pf11-1 and provide experimental evidence that this molecule is involved in the emergence of gametes of the infected erythrocyte (gametogenesis). A mutant parasite clone, whic
Externí odkaz:
https://doaj.org/article/f60f8f62ba934ca6a43c94b624553ffa
Autor:
Christine Scheidig-Benatar, Jose-Juan Lopez-Rubio, Adéla Nacer, Aurélie Claes, Denise Mattei, Amy Roberts, Hiroshi Sakamoto, Mehdi Ghorbal
Publikováno v:
Cellular Microbiology. 17:1205-1216
Plasmodium falciparum virulence is linked to its ability to sequester in post-capillary venules in the human host. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is the main variant surface antigen implicated in this process. Complete
Autor:
D. Channe Gowda, Denise Mattei, Katharine R. Trenholme, Rajeshwara N. Achur, Ali Salanti, Manojkumar Valiyaveettil, Atul Goyal, Suchi Goel, Donald L. Gardiner
Publikováno v:
Proceedings of the National Academy of Sciences. 107:16643-16648
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate the adherence of parasite-infected red blood cells (IRBCs) to various host receptors. A previous study has shown that the parasite protein, cytoadherence-linked asex
Publikováno v:
Cellular Microbiology
SUMO (Small Ubiquitin-like MOdifier) conjugation is a post-translational modification implicated in a variety of cellular functions including transcriptional regulation, nuclear location and signal transduction. Sumoylation, although conserved and vi
Autor:
Irene T. Ling, Takafumi Tsuboi, Hitoshi Otsuki, Denise Mattei, Brian Y. S. Yim Lim, John H. Adams, Motomi Torii, Anthony A. Holder, Osamu Kaneko, Munira Grainger, Hideyuki Iriko
Publikováno v:
Molecular and Biochemical Parasitology. 143:20-28
The Plasmodium falciparum high molecular mass rhoptry protein (‘PfRhopH’) complex is important for parasite growth and comprises three distinct gene products: RhopH1, RhopH2 and RhopH3. We have previously shown that P. falciparum RhopH1 is encode
Autor:
Laurence Florens, Osamu Kaneko, Takafumi Tsuboi, Anthony A. Holder, L. H. Bannister, Anton R. Dluzewski, Denise Mattei, Jeffrey R. Johnson, John R. Yates, Motomi Torii, Brian Y. S. Yim Lim, Irene T. Ling, John M. Hopkins, Munira Grainger
Publikováno v:
Molecular Microbiology. 52:107-118
The first gene characterizing the clag (cytoadherence linked asexual gene) family of Plasmodium falciparum was identified on chromosome 9. The protein product (Clag9) was implicated in cytoadhesion, the binding of infected erythrocytes to host endoth
Autor:
Peter G. Kremsner, Raphael M. Oguariri, Cristina Tena-Tomás, Jürgen F. J. Kun, Denise Mattei, Anne-Catrin Uhlemann
Publikováno v:
Parasitology Research. 90:467-472
Plasmodium falciparum parasites remodel the surface of human erythrocytes on invasion by the insertion of parasite-derived proteins in knob-like protrusions. P. falciparum erythrocyte membrane protein 1 (PfEMP-1), a variant surface antigen, has been