Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Denisa Miklankova"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and aimsRecent studies suggest that empagliflozin reduces total and cardiovascular mortality in both diabetic and nondiabetic subjects. Although the exact mechanism is unclear, it is understood to positively affect myocardial energetics, i
Externí odkaz:
https://doaj.org/article/fa2238b0f7a646cf9584cc6424377b21
Publikováno v:
Journal of Diabetes Research, Vol 2022 (2022)
Introduction. Monounsaturated fatty acids (MUFA) are understood to have therapeutic and preventive effects on chronic complications associated with type 2 diabetes mellitus (T2DM); however, there are differences between individual MUFAs. Although the
Externí odkaz:
https://doaj.org/article/26e94ca82d9c4cec87d8e861d37f6ebe
Autor:
Jan Pitha, Martina Huttl, Hana Malinska, Denisa Miklankova, Hana Bartuskova, Tomas Hlinka, Irena Markova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2825 (2022)
Background: If menopause is really independent risk factor for cardiovascular disease is still under debate. We studied if ovariectomy in the model of insulin resistance causes cardiovascular changes, to what extent are these changes reversible by es
Externí odkaz:
https://doaj.org/article/dbb0000541f04689a0bddee18f8e2500
Autor:
Martina Hüttl, Irena Markova, Denisa Miklankova, Iveta Zapletalova, Martin Poruba, Zuzana Racova, Rostislav Vecera, Hana Malinska
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 45 (2021)
The combination of plant-derived compounds with anti-diabetic agents to manage hepatic steatosis closely associated with diabetes mellitus may be a new therapeutic approach. Silymarin, a complex of bioactive substances extracted from Silybum marianum
Externí odkaz:
https://doaj.org/article/8958765974644291a660f42016709d97
Autor:
Martina Hüttl, Irena Markova, Denisa Miklankova, Iveta Zapletalova, Martin Poruba, Martin Haluzik, Ivana Vaněčkova, Hana Malinska
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11513 (2021)
Recent studies suggest that treatment with SGLT-2 inhibitors can reduce hepatic lipid storage and ameliorate non-alcoholic fatty liver disease (NAFLD) development beyond their glycemic benefits. However, the exact mechanism involved is still unclear.
Externí odkaz:
https://doaj.org/article/5232f2e319d64d328a7424197deea0a9
Autor:
Denisa Miklankova, Irena Markova, Martina Hüttl, Iveta Zapletalova, Martin Poruba, Hana Malinska
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7680 (2021)
Metformin can reduce cardiovascular risk independent of glycemic control. The mechanisms behind its non-glycemic benefits, which include decreased energy intake, lower blood pressure and improved lipid and fatty acid metabolism, are not fully underst
Externí odkaz:
https://doaj.org/article/7ed34ba49cc94f118bc8319975ec889d
Autor:
Irena Markova, Denisa Miklankova, Martina Hüttl, Petr Kacer, Jelena Skibova, Jan Kucera, Radislav Sedlacek, Tereza Kacerova, Ludmila Kazdova, Hana Malinska
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Introduction. The development of metabolic syndrome-associated renal dysfunction is exacerbated by a number of factors including dyslipidemia, ectopic deposition of lipids and their toxic metabolites, impairment of lipid metabolism, and insulin resis
Externí odkaz:
https://doaj.org/article/ab06606989474a81b1ad75c48b777697
Autor:
Martina Hüttl, Irena Markova, Denisa Miklankova, Pavol Makovicky, Terezie Pelikanova, Ondrej Šeda, Lucie Šedová, Hana Malinska
Publikováno v:
Antioxidants, Vol 9, Iss 9, p 803 (2020)
Excessive methylglyoxal (MG) production contributes to metabolic and vascular changes by increasing inflammatory processes, disturbing regulatory mechanisms and exacerbating tissue dysfunction. MG accumulation in adipocytes leads to structural and fu
Externí odkaz:
https://doaj.org/article/7c44588aace54970a1c62f48d7d15748
Autor:
Silvie Hojná, Hana Malínská, Martina Hüttl, Zdeňka Vaňourková, Irena Marková, Denisa Miklánková, Jaroslav Hrdlička, František Papoušek, Jan Neckář, Petr Kujal, Michal Behuliak, Hana Rauchová, Michaela Kadlecová, David Sedmera, Kristýna Neffeová, Eva Zábrodská, Veronika Olejníčková, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116520- (2024)
A combination of liver and heart dysfunction worsens the prognosis of human survival. The aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 inhibitor) has beneficial effects not only on cardiac and renal funct
Externí odkaz:
https://doaj.org/article/ce293d8af73640869fc6eca6e079b0bb
Autor:
Tereza Kacerova, Ludmila Kazdova, Petr Kacer, Irena Markova, Jelena Skibova, Jan Kučera, Denisa Miklankova, Martina Hüttl, Hana Malinska, Radislav Sedlacek
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Journal of Diabetes Research
Journal of Diabetes Research
Introduction. The development of metabolic syndrome-associated renal dysfunction is exacerbated by a number of factors including dyslipidemia, ectopic deposition of lipids and their toxic metabolites, impairment of lipid metabolism, and insulin resis