Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Denisa Miklánková"'
Autor:
Silvie Hojná, Hana Malínská, Martina Hüttl, Zdeňka Vaňourková, Irena Marková, Denisa Miklánková, Jaroslav Hrdlička, František Papoušek, Jan Neckář, Petr Kujal, Michal Behuliak, Hana Rauchová, Michaela Kadlecová, David Sedmera, Kristýna Neffeová, Eva Zábrodská, Veronika Olejníčková, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116520- (2024)
A combination of liver and heart dysfunction worsens the prognosis of human survival. The aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 inhibitor) has beneficial effects not only on cardiac and renal funct
Externí odkaz:
https://doaj.org/article/ce293d8af73640869fc6eca6e079b0bb
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 627 (2024)
Menopause brings about profound physiological changes, including the acceleration of insulin resistance and other abnormalities, in which adipose tissue can play a significant role. This study analyzed the effect of ovariectomy and estradiol substitu
Externí odkaz:
https://doaj.org/article/768b7a49f78c4bcabab8cecc7d5212be
Autor:
Martina Hüttl, Irena Markova, Denisa Miklánková, Iveta Zapletalova, Petr Kujal, Jan Šilhavý, Michal Pravenec, Hana Malinska
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and aims: Low-grade chronic inflammation plays an important role in the pathogenesis of metabolic syndrome, type 2 diabetes and their complications. In this study, we investigated the effects of salsalate, a non-steroidal anti-inflammatory
Externí odkaz:
https://doaj.org/article/43d18ec3736b4092867a31a16cc3da06
Autor:
Jan Šilhavý, Petr Mlejnek, Miroslava Šimáková, Hana Malínská, Irena Marková, Martina Hüttl, Denisa Miklánková, Ludmila Kazdová, Marek Vrbacký, Alena Pecinová, Tomáš Mráček, Michal Pravenec
Publikováno v:
Metabolites, Vol 13, Iss 2, p 192 (2023)
Recently, red beetroot has attracted attention as a health-promoting functional food. Studies have shown that beetroot administration can reduce blood pressure and ameliorate parameters of glucose and lipid metabolism; however, mechanisms underlying
Externí odkaz:
https://doaj.org/article/a687dbf6a0cc4fd38db94b4d81c78b08
Autor:
Silvie Hojná, Hana Rauchová, Hana Malínská, Irena Marková, Martina Hüttl, František Papoušek, Michal Behuliak, Denisa Miklánková, Zdeňka Vaňourková, Jan Neckář, Michaela Kadlecová, Petr Kujal, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112246- (2021)
The new antidiabetic drugs, gliflozins, inhibit sodium-glucose transporter-2 in renal proximal tubules promoting glucose and sodium excretion. This leads not only to a significant improvement of glucose control but also to the reduction of blood pres
Externí odkaz:
https://doaj.org/article/e201a9068c7440d880c7984feaa998e8
Autor:
Hana Malínská, Martina Hüttl, Irena Marková, Denisa Miklánková, Silvie Hojná, František Papoušek, Jan Šilhavý, Petr Mlejnek, Josef Zicha, Jaroslav Hrdlička, Michal Pravenec, Ivana Vaněčková
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2066 (2022)
Gliflozins (inhibitors of sodium-glucose cotransporter 2) show many beneficial actions beyond their antidiabetic effects. The underlying mechanisms of these additional protective effects are still not well understood, especially under non-diabetic co
Externí odkaz:
https://doaj.org/article/a6a72131a5de4a8d9c3d0274808e4d0b
Autor:
Maksym Moskvin, Irena Marková, Hana Malínská, Denisa Miklánková, Martina Hüttl, Olena Oliyarnyk, Ognen Pop-Georgievski, Alexander Zhigunov, Eduard Petrovský, Daniel Horák
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Magnetic γ-Fe2O3/CeOx nanoparticles were obtained by basic coprecipitation/oxidation of iron chlorides with hydrogen peroxide, followed by precipitation of Ce(NO3)3 with ammonia. The appearance of CeOx on the magnetic particle surface was confirmed
Externí odkaz:
https://doaj.org/article/edc17e5e1c024dad8f9b601d581515ec
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and aimsRecent studies suggest that empagliflozin reduces total and cardiovascular mortality in both diabetic and nondiabetic subjects. Although the exact mechanism is unclear, it is understood to positively affect myocardial energetics, i
Externí odkaz:
https://doaj.org/article/fa2238b0f7a646cf9584cc6424377b21
Publikováno v:
Journal of Diabetes Research, Vol 2022 (2022)
Introduction. Monounsaturated fatty acids (MUFA) are understood to have therapeutic and preventive effects on chronic complications associated with type 2 diabetes mellitus (T2DM); however, there are differences between individual MUFAs. Although the
Externí odkaz:
https://doaj.org/article/26e94ca82d9c4cec87d8e861d37f6ebe
Autor:
Martina Hüttl, Irena Markova, Denisa Miklankova, Iveta Zapletalova, Martin Poruba, Zuzana Racova, Rostislav Vecera, Hana Malinska
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 45 (2021)
The combination of plant-derived compounds with anti-diabetic agents to manage hepatic steatosis closely associated with diabetes mellitus may be a new therapeutic approach. Silymarin, a complex of bioactive substances extracted from Silybum marianum
Externí odkaz:
https://doaj.org/article/8958765974644291a660f42016709d97