Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Denisa, Bojkova"'
Autor:
Rebekka Karlowitz, Megan L. Stanifer, Jens Roedig, Geoffroy Andrieux, Denisa Bojkova, Marco Bechtel, Sonja Smith, Lisa Kowald, Ralf Schubert, Melanie Boerries, Jindrich Cinatl, Steeve Boulant, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-14 (2022)
Abstract Pattern recognition receptors (PRRs) and interferons (IFNs) serve as essential antiviral defense against SARS-CoV-2, the causative agent of the COVID-19 pandemic. Type III IFNs (IFN-λ) exhibit cell-type specific and long-lasting functions i
Externí odkaz:
https://doaj.org/article/e0cff6daeb78475a8d5002c6e431347e
Autor:
Andreas Wasilewicz, Julia Zwirchmayr, Benjamin Kirchweger, Denisa Bojkova, Jindrich Cinatl, Holger F. Rabenau, Judith M. Rollinger, Mehdi A. Beniddir, Ulrike Grienke
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
A pigment-depleted extract from the heartwood of Pterocarpus santalinus L. f. (PS-DE) showed promising anti-SARS-CoV-2 activity with an IC50 of 29.9 μg/mL in Caco-2-F03 cells. To determine the potential active constituents within the extract prior t
Externí odkaz:
https://doaj.org/article/c376f21a6ee348b8ae8cc1ebfd1058f4
Autor:
Emily Layer, Sebastian Hoehl, Marek Widera, Denisa Bojkova, Tim Westphal, Rene Gottschalk, Boris Boeddinghaus, Joscha Schork, Sandra Ciesek, Udo Goetsch
Publikováno v:
International Journal of Infectious Diseases, Vol 118, Iss , Pp 126-131 (2022)
Background: International travel poses the risk of importing SARS-CoV-2 infections and introducing new viral variants into the country of destination. Established measures include mandatory quarantine with the opportunity to abbreviate it with a nega
Externí odkaz:
https://doaj.org/article/3da054506d78471e9644be69b0b0fb36
Autor:
Denisa Bojkova, Tamara Rothenburger, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/32d4ffb094894528b54b4ba4459985d6
Autor:
Patrick Carius, Annemarie Jungmann, Marco Bechtel, Alexander Grißmer, Annette Boese, Gilles Gasparoni, Abdulrahman Salhab, Ralf Seipelt, Klaus Urbschat, Clémentine Richter, Carola Meier, Denisa Bojkova, Jindrich Cinatl, Jörn Walter, Nicole Schneider‐Daum, Claus‐Michael Lehr
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract In the development of orally inhaled drug products preclinical animal models regularly fail to predict pharmacological as well as toxicological responses in humans. Models based on human cells and tissues are potential alternatives to animal
Externí odkaz:
https://doaj.org/article/bd657f46b48c4b599d1780adf01cc0eb
Autor:
Denisa Bojkova, Philipp Reus, Leona Panosch, Marco Bechtel, Tamara Rothenburger, Joshua D. Kandler, Annika Pfeiffer, Julian U.G. Wagner, Mariana Shumliakivska, Stefanie Dimmeler, Ruth Olmer, Ulrich Martin, Florian W.R. Vondran, Tuna Toptan, Florian Rothweiler, Richard Zehner, Holger F. Rabenau, Karen L. Osman, Steven T. Pullan, Miles W. Carroll, Richard Stack, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl, Jr.
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105944- (2023)
Summary: Reliable, easy-to-handle phenotypic screening platforms are needed for the identification of anti-SARS-CoV-2 compounds. Here, we present caspase 3/7 activity as a readout for monitoring the replication of SARS-CoV-2 isolates from different v
Externí odkaz:
https://doaj.org/article/4a88cf04c85349bf88133734b02945c5
Autor:
Tamara Rothenburger, Dominique Thomas, Yannick Schreiber, Paul R. Wratil, Tamara Pflantz, Kirsten Knecht, Katie Digianantonio, Joshua Temple, Constanze Schneider, Hanna-Mari Baldauf, Katie-May McLaughlin, Florian Rothweiler, Berna Bilen, Samira Farmand, Denisa Bojkova, Rui Costa, Nerea Ferreirós, Gerd Geisslinger, Thomas Oellerich, Yong Xiong, Oliver T. Keppler, Mark N. Wass, Martin Michaelis, Jindrich Cinatl
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background SAMHD1 mediates resistance to anti-cancer nucleoside analogues, including cytarabine, decitabine, and nelarabine that are commonly used for the treatment of leukaemia, through cleavage of their triphosphorylated forms. Hence, SAMH
Externí odkaz:
https://doaj.org/article/d96327060ccf4b409f6c8453b5c904c2
Autor:
Katie-May McLaughlin, Denisa Bojkova, Joshua D. Kandler, Marco Bechtel, Philipp Reus, Trang Le, Florian Rothweiler, Julian U. G. Wagner, Andreas Weigert, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 1212-1225 (2021)
The coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Most SARS-CoV-2 infections are mild or even asymptomatic. However, a small fraction of infected individuals develops severe, life-threatening disease, which is caused by an unc
Externí odkaz:
https://doaj.org/article/da1dcab2615b4e5e8ee1edd4276b1c88
Autor:
Bruce Schultz, Andrea Zaliani, Christian Ebeling, Jeanette Reinshagen, Denisa Bojkova, Vanessa Lage-Rupprecht, Reagon Karki, Sören Lukassen, Yojana Gadiya, Neal G. Ravindra, Sayoni Das, Shounak Baksi, Daniel Domingo-Fernández, Manuel Lentzen, Mark Strivens, Tamara Raschka, Jindrich Cinatl, Lauren Nicole DeLong, Phil Gribbon, Gerd Geisslinger, Sandra Ciesek, David van Dijk, Steve Gardner, Alpha Tom Kodamullil, Holger Fröhlich, Manuel Peitsch, Marc Jacobs, Julia Hoeng, Roland Eils, Carsten Claussen, Martin Hofmann-Apitius
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a flood of experiments, analyses, hypotheses, and publications, especially in the field of drug repurposing.
Externí odkaz:
https://doaj.org/article/18b0a7d14b824058a3306b2a9990465c
Autor:
Bernhard Ellinger, Denisa Bojkova, Andrea Zaliani, Jindrich Cinatl, Carsten Claussen, Sandra Westhaus, Oliver Keminer, Jeanette Reinshagen, Maria Kuzikov, Markus Wolf, Gerd Geisslinger, Philip Gribbon, Sandra Ciesek
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-10 (2021)
Measurement(s) cytotoxicity • killing by virus of host cell Technology Type(s) bright-field microscopy Factor Type(s) concentration • incubation time Sample Characteristic - Organism Homo sapiens Machine-accessible metadata file describing the re
Externí odkaz:
https://doaj.org/article/bd461bec118c4a32a661a0394ac4282f