Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Denis Zeyer"'
Autor:
Iskander Khusainov, Bulat Fatkhullin, Simone Pellegrino, Aydar Bikmullin, Wen-ti Liu, Azat Gabdulkhakov, Amr Al Shebel, Alexander Golubev, Denis Zeyer, Natalie Trachtmann, Georg A. Sprenger, Shamil Validov, Konstantin Usachev, Gulnara Yusupova, Marat Yusupov
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Upon transition to stationary phase or upon stress, bacteria limit protein synthesis through small inhibitory proteins that bind the ribosome. Here the authors decipher the interaction mode of the bacterial ribosome silencing factor (RsfS) at atomic
Externí odkaz:
https://doaj.org/article/1ad738db839640ba9241f8a79ce45330
Publikováno v:
Phytochemistry Reviews. 19:1141-1156
Plant natural products (PNP) (e.g., secondary vegetal metabolites and their derivatives) have been a productive source of active ingredients for the pharmaceutical industry. The High Throughput Screening of Plant Natural Products (PNP-HTS) with extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::976a7545d9e933ad9c95c801cc46adb5
https://doi.org/10.1007/s11101-019-09612-4
https://doi.org/10.1007/s11101-019-09612-4
Autor:
Gilles Ferry, Philip M. Kubara, Bruno Pfeiffer, Jean-Paul Renaud, Stéphane Léonce, Celine Bossard, Patrick Casara, Michelle Prudhomme, Guillaume de Nanteuil, Roy M. Golsteyn, Alain Pierré, Jean A. Boutin, Michel Wierzbicki, Denis Zeyer, Aurélie Studeny
Publikováno v:
Life Sciences. 89:259-268
Aims We have developed biochemical and cell based assays to characterize small therapeutic molecules that inhibit the DNA damage checkpoint enzyme, Chk1 (Checkpoint kinase 1). Main methods To prepare a screen of large chemical libraries, we purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f067b8bae392e7b62d860d8d5d5f5708
https://doi.org/10.1016/j.lfs.2011.06.010
https://doi.org/10.1016/j.lfs.2011.06.010
Autor:
Noelle Potier, Dino Moras, Steven G. Blanchard, Johan Auwerx, Pierre Bac, Jean-Paul Renaud, Denis Zeyer, Frédéric Picard, Laurent Dubuquoy, Lisa M. Leesnitzer, Pierre Desreumaux, Kelli D. Plunket, Marie-France Champy, Laurent Gelman, Joseph Vamecq, Stéphane Rocchi
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2001, 8 (4), pp.737-747. ⟨10.1016/s1097-2765(01)00353-7⟩
Molecular Cell, Elsevier, 2001, 8 (4), pp.737-747. ⟨10.1016/s1097-2765(01)00353-7⟩
FMOC-L-Leucine (F-L-Leu) is a chemically distinct PPARgamma ligand. Two molecules of F-L-Leu bind to the ligand binding domain of a single PPARgamma molecule, making its mode of receptor interaction distinct from that of other nuclear receptor ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4bca30d0950145910b540c5481a330
https://doi.org/10.1016/s1097-2765(01)00353-7
https://doi.org/10.1016/s1097-2765(01)00353-7
Autor:
Cédric Atmanene, Denis Zeyer, A Van Dorsselaer, Valerie Vivat Hannah, Sarah Sanglier-Cianférani
Publikováno v:
Future medicinal chemistry. 2(1)
The success of early drug-discovery programs depends on the adequate combination of complementary and orthogonal technologies allowing hit/lead compounds to be optimized and improve therapeutic activity. Among the available biophysical methods, nativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f56186924f58e3f27a9ebb421d950a
https://pubmed.ncbi.nlm.nih.gov/21426045
https://pubmed.ncbi.nlm.nih.gov/21426045
Autor:
Dino Moras, Sarah Sanglier, Denis Zeyer, Roland Schüle, Catherine Stehlin-Gaon, Dominica Willmann, Jean-Paul Renaud, Alain Van Dorsselaer
Publikováno v:
Nature structural biology. 10(10)
Retinoids regulate gene expression through binding to the nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs). In contrast, no ligands for the retinoic acid receptor-related orphan receptors beta and gamma (ROR beta and gamma) have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7db69cf795b52e3c16359ae140cef7
https://pubmed.ncbi.nlm.nih.gov/12958591
https://pubmed.ncbi.nlm.nih.gov/12958591