Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Denis W. King"'
Autor:
C. Pieri, V. Balakrishnan, P. Doherty, Denis W. King, David Z. Lubowski, V. Patton, K. C. Phan-Thien
Publikováno v:
Techniques in Coloproctology. 24:173-179
Slow transit constipation is characterised by prolonged colonic transit and reliance on laxatives. The pathophysiology is poorly understood and in its most severe form, total colectomy with ileorectal anastomosis is the final treatment option. We pre
Autor:
Hong-Zhuan Chen, Olle Johansson, Karan Rao, Dayashan Shevy Perera, Lu Liu, Huy Le, Li Zhang, Ka Ming Yeh, Denis W. King, Irit Markus, David Z. Lubowski
Publikováno v:
Journal of Gastroenterology. 54:994-1006
Cystic fibrosis transmembrane conductance regulator (CFTR) was recently found in the enteric nervous system, where its role is unclear. We aimed to identify which enteric neuronal structures express CFTR, whether CFTR modulates enteric neurotransmiss
Publikováno v:
ANZ Journal of Surgery. 88:311-315
Background Surveillance colonoscopy allows for the early detection and improved treatment outcomes in colorectal neoplasms but compliance rates and factors require further investigation. Methods This is a retrospective cohort study examining 816 pati
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 340:27-36
Hemokinin-1 (HK-1) is a newly identified tachykinin, originating from the immune system rather than neurons, and may participate in the immune and inflammatory response. In colonic mucosa of inflammatory bowel disease (IBD) patients, upregulation of
Autor:
Elizabeth Burcher, Qin Du, Fei Shang, Denis W. King, David Z. Lubowski, Fiona J. Warner, Lu Liu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 324:170-178
Neurokinin A (NKA) is an important spasmogen in human colon. We examined inflammatory disease-related changes in the tachykinin NK(2) receptor system in human sigmoid colon circular muscle, using functional, radioligand binding, and quantitative reve
Publikováno v:
World Journal of Surgery. 31:1496-1501
Patients with synchronous colorectal liver metastases are thought to have a less favorable prognosis than those with colorectal cancer alone. Surgical treatment options are controversial, be it synchronous resection or staged resection. This study co
Publikováno v:
Digestive diseases and sciences. 60(5)
Prostaglandin E2 (PGE2) is the dominant prostaglandin in the colon and is associated with colonic inflammation. PGE2 levels are regulated not only by cyclooxygenases (COX-1 and COX-2) but also by 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the m
Autor:
Denis W. King, Phil G. Dinning, Peter A. Bampton, David Z. Lubowski, Ian J. Cook, M. L. Kennedy
Publikováno v:
Diseases of the Colon & Rectum. 48:1777-1784
Both motor and sensory dysfunction have been implicated in the pathogenesis of obstructed defecation. We have found that despite preservation of a defecatory urge, patients with obstructed defecation have lost the normal predefecatory augmentation in
Publikováno v:
The Australian and New Zealand Journal of Obstetrics and Gynaecology. 45:195-200
Objective: The aim of the study was to analyse the functional outcome of women undergoing a laparoscopic posterior compartment repair in the presence of anterior or apical compartment dysfunction. Design: Prospective cohort study. Methods: Forty wome
Publikováno v:
Diseases of the Colon & Rectum. 48:1207-1212
The duration of physiologic action of topical glyceryl trinitrate in the management of anal fissure has been the source of some controversy. This study was designed to assess the manometric effect of glyceryl trinitrate on internal sphincter resting