Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

Autor: David W Eyre, Sheila F Lumley, Denise O'Donnell, Mark Campbell, Elizabeth Sims, Elaine Lawson, Fiona Warren, Tim James, Stuart Cox, Alison Howarth, George Doherty, Stephanie B Hatch, James Kavanagh, Kevin K Chau, Philip W Fowler, Jeremy Swann, Denis Volk, Fan Yang-Turner, Nicole Stoesser, Philippa C Matthews, Maria Dudareva, Timothy Davies, Robert H Shaw, Leon Peto, Louise O Downs, Alexander Vogt, Ali Amini, Bernadette C Young, Philip George Drennan, Alexander J Mentzer, Donal T Skelly, Fredrik Karpe, Matt J Neville, Monique Andersson, Andrew J Brent, Nicola Jones, Lucas Martins Ferreira, Thomas Christott, Brian D Marsden, Sarah Hoosdally, Richard Cornall, Derrick W Crook, David I Stuart, Gavin Screaton, Oxford University Hospitals Staff Testing Group, Timothy EA Peto, Bruno Holthof, Anne-Marie O'Donnell, Daniel Ebner, Christopher P Conlon, Katie Jeffery, Timothy M Walker

Publikováno v: eLife, Vol 9 (2020)

We conducted voluntary Covid-19 testing programmes for symptomatic and asymptomatic staff at a UK teaching hospital using naso-/oro-pharyngeal PCR testing and immunoassays for IgG antibodies. 1128/10,034 (11.2%) staff had evidence of Covid-19 at some

Externí odkaz: https://doaj.org/article/e0a0320c53944dff884e403ea0af8988

Catwalk : identifying closely related sequences in large microbial sequence databases

Autor: Denis Volk, Fan Yang-Turner, Xavier Didelot, Derrick W. Crook, David Wyllie

There is a need to identify microbial sequences that may form part of transmission chains, or that may represent importations across national boundaries, amidst large numbers of SARS-CoV-2 and other bacterial or viral sequences. Reference-based compr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1094b8e62d8baf9814ada5087cb847d3
http://wrap.warwick.ac.uk/167169/1/WRAP-Catwalk-identifying-closely-related-sequences-in-large-microbial-sequence-databases-Didelot-22.pdf

Author response: Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

Autor: Nellia Sande, Hannah Chase, Alan Chetwynd, Connor Thompson, Fiona Warren, Sonam Rughani, Jonathan Drake, Callum E. Harries, Rebecca te Water Naudé, Fredrik Karpe, Claire Sutton, Gabriella Kelly, Stoyan Dimitrov, Denis Volk, Olivia Ambler, Lucianne Smith, Michelle Gates, Adam J. R. Watson, Sheila F Lumley, Daniel Ebner, Gareth Watson, Tariq Ahmed-Firani, Kirsty Harper, Philip Cowie, Kaisha Patel, Bruno Holthof, Alison Howarth, Hannah Laurenson-Schafer, Christian Holland, Jane Philips, Rachel Turford, Rebecca K Young, Charlotte Lee, Philip W. Fowler, Julie Dequaire, Caitlin Rigler, James Kavanagh, Joshua Morton, Mark Campbell, Brian D. Marsden, George Doherty, Tracey Mitchell, Saxon Pattenden, Denise O'Donnell, Susan Wareing, Maria Robles, Euan Joseph McGivern, Samuel Scott, Timothy M. Walker, Laura Warren, Justyna Szczurkowska, Richard Kirton, Angus Livingstone, Emma-Jane Simons, Thomas Foord, Kenzo Motohashi, Jocelyn Lf Ward, Jeremy Swann, Francesca Back, David S Kim, Gabriella DAmato, Monique Andersson, David Axten, Seren Hannah Rose Waite, Matt J. Neville, Fan Yang-Turner, Cameron East, Holly Hendron, Elizabeth Sims, Hannah Danbury, Louise O Downs, Stefan Kourdov, Oscar Deal, Elaine Lawson, Kyla Smit, Robert Shaw, Leon Peto, Gavin R. Screaton, Trisha Bellinger, Joseph D. Wilson, Lucas Martins Ferreira, Adan Taylor, Krupa Ravi, David I. Stuart, Marcus English, Richard J. Cornall, Chris Jb Mason, Annabel Killen, Michael Luciw, Constantinos Savva, Lisa Butcher, Stuart Cox, Donal T. Skelly, Owen Sweeney, Derrick W. Crook, Maria Dudareva, Alexander J. Mentzer, Ruth Moroney, Sarah Wright, Zoe de Toledo, Roshni Ray, Thomas Christie, Lisa Morgan, Philippa C Matthews, Nicola Jones, Katherine O'Byrne, Mary Kumarendran, Nicole Stoesser, Nurul Huda Mohamad Fadzillah, Anne-Marie O'Donnell, Isabel Tol, Philip G. Drennan, Tim James, Katie Jeffery, Gemma Pill, Lydia Rylance-Knight, Stephanie B Hatch, Kevin K Chau, Evie Rothwell, Tim Davies, Lancelot J. Millar, Tim E. A. Peto, Evelyn Qian, Merline Tabirao, Thomas Christott, Heather Nevard, Liam J Peck, Madeleine E Oliver, Mary McKnight, Christopher P. Conlon, Conor Hennesey, Andrew Brent, Sarah Peters, Anita Justice, Kathryn Cann, James Gunnell, Thomas G Ritter, Claudia Salvagno, Stephanie Santos-Paulo, Vicki Wharton, S A Johnson, Samuel Sussmes, Harry Ward, Sven A. Kerneis, Edward Wa Harris, Matthew Wedlich, Alexandra S Mighiu, Ali Amini, Alexander Grassam-Rowe, Gregory D Howgego, Bernadett Gergely, Rosie Freer, Bernadette C. Young, Thomas B King, Sarah Hoosdally, Alexander Vogt, Imogen C Vorley, David W Eyre, Gerald Jesuthasan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::725ccabce85f7b656730aa879ed62c97
https://doi.org/10.7554/elife.60675.sa2

Scalable Pathogen Pipeline Platform (SP^3): enabling unified genomic data analysis with elastic cloud computing

Autor: Tim E. A. Peto, Thomas R. Connor, Matthew J. Bull, Fan Yang-Turner, Jeremy Swann, Derrick W. Crook, Sarah Hoosdally, Denis Volk, Philip W. Fowler

Publikováno v: CLOUD

Pathogen genomic data analysis can be extremely bespoke and diverse. This paper presents our plan and progress towards creating a Scalable Pathogen Pipeline Platform (SP^3) providing an efficient and unified process of collecting, analysing and compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389e907fc0cdda30b28d48e72454fb1f
https://doi.org/10.1109/cloud.2019.00083

Fast–Slow Partially Hyperbolic Systems Versus Freidlin–Wentzell Random Systems

Autor: Carlangelo Liverani, Jacopo De Simoi, Christophe Poquet, Denis Volk

Publikováno v: Journal of Statistical Physics
Journal of Statistical Physics, Springer Verlag, 2017, 166 (3-4), pp.650-679. ⟨10.1007/s10955-016-1628-3⟩

We consider a simple class of fast-slow partially hyperbolic dynamical systems and show that the (properly rescaled) behaviour of the slow variable is very close to a Friedlin--Wentzell type random system for times that are rather long, but much shor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c5629fb4577e256f7a471dd946ef1f
https://hal.archives-ouvertes.fr/hal-02071326