Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Denis Vecellio Reane"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Ca2+ ions serve as pleiotropic second messengers in the cell, regulating several cellular processes. Mitochondria play a fundamental role in Ca2+ homeostasis since mitochondrial Ca2+ (mitCa2+) is a key regulator of oxidative metabolism and cell death
Externí odkaz:
https://doaj.org/article/1e77b78c320744f09b7d5e2cba0052ea
Autor:
Simona Feno, Fabio Munari, Gaia Gherardi, Denis Vecellio Reane, Donato D’Angelo, Antonella Viola, Rosario Rizzuto, Anna Raffaello
Publikováno v:
Bio-Protocol, Vol 13, Iss 1 (2023)
Skeletal muscle, one of the most abundant tissue in the body, is a highly regenerative tissue. Indeed, compared to other tissues that are not able to regenerate after injury, skeletal muscle can fully regenerate upon mechanically, chemically, and inf
Externí odkaz:
https://doaj.org/article/0a391f88df03453a8343e992840db18a
Autor:
Gaia Butera, Denis Vecellio Reane, Marta Canato, Laura Pietrangelo, Simona Boncompagni, Feliciano Protasi, Rosario Rizzuto, Carlo Reggiani, Anna Raffaello
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109087- (2021)
Summary: Parvalbumin (PV) is a cytosolic Ca2+-binding protein highly expressed in fast skeletal muscle, contributing to an increased relaxation rate. Moreover, PV is an “atrogene” downregulated in most muscle atrophy conditions. Here, we exploit
Externí odkaz:
https://doaj.org/article/06e492fc39c54bbe9ad2bb2321f44d4b
Autor:
Denis Vecellio Reane, Cristina Cerqua, Sabrina Sacconi, Leonardo Salviati, Eva Trevisson, Anna Raffaello
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2517 (2022)
Alternative splicing, the process by which exons within a pre-mRNA transcript are differentially joined or skipped, is crucial in skeletal muscle since it is required both during myogenesis and in post-natal life to reprogram the transcripts of contr
Externí odkaz:
https://doaj.org/article/29124d73ace84cbfaeb089fee7e8cbe5
Autor:
Marta Canato, Paola Capitanio, Lina Cancellara, Luigi Leanza, Anna Raffaello, Denis Vecellio Reane, Lorenzo Marcucci, Antonio Michelucci, Feliciano Protasi, Carlo Reggiani
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Mice (Y522S or YS), carrying a mutation of the sarcoplasmic reticulum (SR) Ca2+ release channel of skeletal muscle fibers (ryanodine receptor type-1, RyR1) which causes Ca2+ leak, are a widely accepted and intensively studied model for human malignan
Externí odkaz:
https://doaj.org/article/95fb6d4c1e4747f793e73027fb9100f5
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Calcium ions are highly versatile intracellular signals that regulate many cellular processes. The key to achieving this pleiotropic role is the spatiotemporal control of calcium concentration evoked by an extensive molecular repertoire of signalling
Autor:
Gino A Cortopassi, Agnese De Mario, Julia M. Hill, Denis Vecellio Reane, Anna Tosatto, Rosario Rizzuto, Gyorgy Szabadkai, Janos Kriston-Vizi, Cristina Mammucari, Robin Ketteler
Publikováno v:
Cell Reports
Summary The mitochondrial calcium uniporter (MCU), the highly selective channel responsible for mitochondrial Ca2+ entry, plays important roles in physiology and pathology. However, only few pharmacological compounds directly and selectively modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4555ad3f0bee378e209c9d9cd716d
http://hdl.handle.net/11577/3394520
http://hdl.handle.net/11577/3394520
Autor:
Rosario Rizzuto, Alessandra Castegna, Denis Vecellio Reane, Fabio Munari, Simona Feno, Anna Raffaello, Bénédicte Chazaud, Antonella Viola, Dieu-Huong Hoang, Rosanna Gissi
Damaged skeletal muscle can regenerate because of the coordinated action of immune cells with muscle stem cells, called satellite cells. Proinflammatory macrophages infiltrate skeletal muscle soon after injury to sustain the proliferation of satellit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca964f794f9ff6efe1918f7bcf6c6f4
http://hdl.handle.net/11577/3405011
http://hdl.handle.net/11577/3405011
Autor:
Carlo Reggiani, Simona Boncompagni, Feliciano Protasi, Gaia Butera, Anna Raffaello, Laura Pietrangelo, Marta Canato, Denis Vecellio Reane, Rosario Rizzuto
Publikováno v:
Cell Reports
Cell Reports, Vol 35, Iss 5, Pp 109087-(2021)
Cell Reports, Vol 35, Iss 5, Pp 109087-(2021)
Summary Parvalbumin (PV) is a cytosolic Ca2+-binding protein highly expressed in fast skeletal muscle, contributing to an increased relaxation rate. Moreover, PV is an “atrogene” downregulated in most muscle atrophy conditions. Here, we exploit m