Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Denis V. Antonets"'
Autor:
Larisa I. Karpenko, Evgeny K. Apartsin, Sergei G. Dudko, Ekaterina V. Starostina, Olga N. Kaplina, Denis V. Antonets, Ekaterina A. Volosnikova, Boris N. Zaitsev, Anastasiya Yu. Bakulina, Aliya G. Venyaminova, Alexander A. Ilyichev, Sergei I. Bazhan
Publikováno v:
Vaccines, Vol 8, Iss 4, p 718 (2020)
Background: According to current data, an effective Ebola virus vaccine should induce both humoral and T-cell immunity. In this work, we focused our efforts on methods for delivering artificial T-cell immunogen in the form of a DNA vaccine, using gen
Externí odkaz:
https://doaj.org/article/f8d514710d984195abfb176cba4ea5e6
Autor:
Andrey P. Rudometov, Anton N. Chikaev, Nadezhda B. Rudometova, Denis V. Antonets, Alexander A. Lomzov, Olga N. Kaplina, Alexander A. Ilyichev, Larisa I. Karpenko
Publikováno v:
Vaccines, Vol 7, Iss 3, p 83 (2019)
The construction of artificial proteins using conservative B-cell and T-cell epitopes is believed to be a promising approach for a vaccine design against diverse viral infections. This article describes the development of an artificial HIV-1 immunoge
Externí odkaz:
https://doaj.org/article/612d8625367242a99159b8cac30832ea
Autor:
Sergei I. Bazhan, Denis V. Antonets, Larisa I. Karpenko, Svetlana F. Oreshkova, Olga N. Kaplina, Ekaterina V. Starostina, Sergei G. Dudko, Sofia A. Fedotova, Alexander A. Ilyichev
Publikováno v:
Vaccines, Vol 7, Iss 2, p 34 (2019)
Background: The lack of effective vaccines against Ebola virus initiates a search for new approaches to overcoming this problem. The aim of the study was to design artificial polyepitope T-cell immunogens—candidate DNA vaccines against Ebola virus
Externí odkaz:
https://doaj.org/article/168ed184e35a4b61a3c1f7978365f8b9
Autor:
Ian Toma, Myron Schultz, Bernd Seilheimer, Tisha Jepson, Maxim Ri, Georges St. Laurent, Michael R. Tackett, Jianhua Zhou, Konstantin Cesnulevicius, Denis V. Antonets, Timothy A. McCaffrey, Dmitry Shtokalo
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
BMC Genomics
BMC Genomics
Background Despite proven therapeutic effects in inflammatory conditions, the specific mechanisms of phytochemical therapies are not well understood. The transcriptome effects of Traumeel (Tr14), a multicomponent natural product, and diclofenac, a no
Autor:
Marina P. Bogryantseva, Evgenii А. Ryzhikov, Polina Yu Torzhkova, Denis V. Antonets, Natal’ya V Danil’chenko, Ivan M. Susloparov, Нечаева Елена Августовна (Ru), Galina S. Onkhonova, T. V. Tregubchak, Stepan A. Pyankov, Andrei S. Gudymo, Aleksandr B Ryzhikov, Ilnaz R. Imatdinov, Rinat A. Maksyutov, E. D. Danilenko, Sergei A. Bodnev, Elena V. Gavrilova, Ekaterina S. Sleptsova, Anastasiya A. Moiseeva, Vladimir N. Petrov, Olga G. Pyankova, Oleg V. Pyankov, Oleg S. Taranov, E. A. Nechaeva
Publikováno v:
Annals of the Russian academy of medical sciences. 76:5-19
Background: In 2020, the pandemic caused by novel coronavirus infection has become one of the most critical global health challenges during the past century. The lack of a vaccine, as the most effective way to control the novel infection, has prompte
Autor:
Denis V. Antonets, Larisa I. Karpenko, Ekaterina V Starostina, Tatyana N. Ilyicheva, Olga Y. Volkova, Bazhan Si, Olga N. Kaplina, Anastasiya Yu. Bakulina, Vasiliy Y. Marchenko
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:3196-3212
The polyepitope strategy is promising approach for successfully creating a broadly protective flu vaccine, which targets T-lymphocytes (both CD4+ and CD8+) to recognise the most conserved epitopes of viral proteins. In this study, we employed a compu
Autor:
Dmitry Shtokalo, Daniel Jones, Yuri Vyatkin, Denis V. Antonets, Timothy A. McCaffrey, Eleanor A.J. Battison, Joel T. Nigg, Georges St. Laurent
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-17 (2020)
BMC Medical Genomics
BMC Medical Genomics
BackgroundA variety of DNA-based methods have been applied to identify genetic markers of attention deficit hyperactivity disorder (ADHD), but the connection to RNA-based gene expression has not been fully exploited.MethodsUsing well defined cohorts
Autor:
Lu Tang, Yue Chen, Fang Wang, Philipp Kapranov, Xiang You, DingDing Cai, Dongyang Xu, Denis V. Antonets, Xueer Han, Huifen Cao, Estelle Nicolas, Ye Cai, Huifang Wang, Maxim Ri, Yao Qi, Fan Gao, Yuri Vyatkin
Publikováno v:
BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-24 (2021)
BMC Biology, Vol 19, Iss 1, Pp 1-24 (2021)
Background The majority of the human genome is transcribed in the form of long non-coding (lnc) RNAs. While these transcripts have attracted considerable interest, their molecular mechanisms of function and biological significance remain controversia
Autor:
Zeynep Arslan, Maha Alfaraidy, Georges St. Laurent, Dmitry Shtakalo, Tisha Jepson, Michael R. Tackett, Yinglei Lai, Richard J. Katz, Ramesh Mazhari, Ian Toma, Zhaoquing Yang, Richard Wargodsky, Denis V. Antonets, Justin Ertle, Timothy A. McCaffrey, Palak Shah, Jonathan S. Reiner, Ju H Kim, Zachary Falk, Daniel B. Jones, Emily Aledort
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
Background Cardiovascular disease had a global prevalence of 523 million cases and 18.6 million deaths in 2019. The current standard for diagnosing coronary artery disease (CAD) is coronary angiography. Surprisingly, despite well-established clinical
Autor:
Durymanov Ag, Tatyana N. Ilyicheva, Olga N. Kaplina, Vasiliy Y. Marchenko, Larisa I. Karpenko, Ekaterina V Starostina, Svetlana F. Oreshkova, Bazhan Si, Denis V. Antonets
Publikováno v:
Vaccines
Volume 8
Issue 3
Vaccines, Vol 8, Iss 448, p 448 (2020)
Volume 8
Issue 3
Vaccines, Vol 8, Iss 448, p 448 (2020)
Background: Development of a universal vaccine capable to induce antibody responses against a broad range of influenza virus strains attracts growing attention. Hemagglutinin stem and the exposed fragment of influenza virus M2 protein are promising t