Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Denis Tsz-Ming Ip"'
Autor:
Mary M.Y. Waye, Yan Wang, Wai Kit Law, David Chi-Cheong Wan, Wei-Cheng Liang, Tzi Bun Ng, Denis Tsz-Ming Ip, Wen Liang Pan
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Acetylcholinesterase inhibitors are prominent alternative in current clinical treatment for AD patients. Therefore, there is a continued need to search for novel AChEIs with good clinical efficacy and less side effects. By using our in-house natural
Autor:
Wan-Fu Yue, Yun-gen Miao, Jian-Mei Liu, Guang-Li Li, Chuan-Xi Zhang, Xing-hua Li, Denis Tsz-Ming Ip, Wan Chi Cheong David, Xiaofeng Wu
Publikováno v:
Molecular Biology Reports. 36:329-335
This novel orange fluorescent protein (OFP) emits brilliant orange fluorescent light. OFP has high fluorescence quantum yield, fast maturation rate, and stability, which imply this protein should be the most favorable biotechnological tools used to i
Autor:
Randy Chi Fai Cheung, John Wong, David Chi-Cheong Wan, Denis Tsz-Ming Ip, Winston Yan Wang, Tzi Bun Ng
Publikováno v:
Applied biochemistry and biotechnology. 179(7)
This study aimed to investigate fragments derived from human and bovine lactoferrins for ability to inhibit nuclear translocation of HIV-1 integrase. It was shown that human lactoferricin, human lactoferrin 1-11, and bovine lactoferrampin reduced nuc
Autor:
Wei-Cheng Liang, David Chi-Cheong Wan, Mary M.Y. Waye, Tzi Bun Ng, Wen Liang Pan, Wai Kit Law, Denis Tsz-Ming Ip, Jianshu Hu, Yan Wang
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 21(11)
Purpose C-X-C chemokine receptor type 4 (CXCR4) signaling has been demonstrated to be involved in cancer invasion and migration; therefore, CXCR4 antagonist can serve as an anti-cancer drug by preventing tumor metastasis. This study aimed to identify
Autor:
Richard Kay, Chi Pui Pang, David Chi Cheong Wan, Denis Tsz-Ming Ip, Lapkay Law, Karl Wah Keung Tsim, Walter K.K. Ho, Jean Woo, Wing-Tai Cheung
Publikováno v:
Movement Disorders. 14:225-229
Parkinson's disease (PD) is a neurodegenerative disease caused by a multitude of environmental, neurochemical, and genetic factors. The gene for human dopamine D4 receptor (DRD4) has been considered as a plausible candidate for the pathogenesis of PD
Autor:
Wan Gang Gu, David Chi Cheong Wan, Sijie Liu, Xuan Zhang, Yan Wang, Yong-Tang Zheng, Joseph H. Chan, Denis Tsz-Ming Ip
Publikováno v:
Chemico-biological interactions. 213
Translocation of viral integrase (IN) into the nucleus is a critical precondition of integration during the life cycle of HIV, a causative agent of Acquired Immunodeficiency Syndromes (AIDS). As the first discovered cellular factor to interact with I
Autor:
David Chi-Cheong Wan, Roy Chi Yan Choi, Karl Wah Keung Tsim, Huangquan Lin, Denis Tsz-Ming Ip, Kam-Leung Chan
Publikováno v:
Chemico-biological interactions. 187(1-3)
Acetylcholinesterase (AChE) (EC. 3.1.1.7) is the acetylcholine-hydrolyzing enzyme that plays an essential role on cholinergic neurotransmission at the synapses of the brain and at the neuromuscular junctions. In order to gain insight into the molecul
Publikováno v:
Marine biotechnology (New York, N.Y.). 9(4)
A novel orange fluorescent protein (OFP) was cloned from the tentacles of Cnidarian tube anemone Cerianthus sp. It consists of 222 amino acid residues with a calculated molecular mass of 25.1 kDa. A BLAST protein sequence homology search revealed tha
Autor:
Denis Tsz-Ming Ip, Mark Bycroft, Kam-Bo Wong, Siu-Hong Chan, Mark D. Allen, David Chi Cheong Wan
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 60:340-341
A novel orange fluorescent protein, with excitation and emission maxima at 548 and 565 nm, respectively, from the Cnidaria tube anemone Cerianthus sp. has been cloned and overexpressed in Escherichia coli. The orange fluorescent protein has been crys
Autor:
Wan-Gang Gu, Liu-Meng Yang, David Chi-Cheong Wan, Xuan Zhang, Denis Tsz-Ming Ip, Yong-Tang Zheng
Publikováno v:
FEBS Letters. (18):3461-3468
The interaction between HIV-1 integrase and LEDGF/P75 has been validated as a target for anti-HIV drug development. Based on the crystal structure of integrase in complex with LEDGF/P75, a library containing 80 thousand natural compounds was filtered