Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Denis Torre"'
Autor:
Denis Torre, Nancy J. Francoeur, Yael Kalma, Ilana Gross Carmel, Betsaida S. Melo, Gintaras Deikus, Kimaada Allette, Ron Flohr, Maya Fridrikh, Konstantinos Vlachos, Kent Madrid, Hardik Shah, Ying-Chih Wang, Shwetha H. Sridhar, Melissa L. Smith, Efrat Eliyahu, Foad Azem, Hadar Amir, Yoav Mayshar, Ivan Marazzi, Ernesto Guccione, Eric Schadt, Dalit Ben-Yosef, Robert Sebra
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Human preimplantation development involves extensive remodeling of RNA expression and splicing. However, its transcriptome has been compiled using short-read sequencing data, which fails to capture most full-length mRNAs. Here, we generate a
Externí odkaz:
https://doaj.org/article/c3c20aad7f8e43afbec8ac8c0333cada
Autor:
Sean M. Gross, Mark A. Dane, Rebecca L. Smith, Kaylyn L. Devlin, Ian C. McLean, Daniel S. Derrick, Caitlin E. Mills, Kartik Subramanian, Alexandra B. London, Denis Torre, John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Cemal Erdem, Nicholas Lyons, Ted Natoli, Sarah Pessa, Xiaodong Lu, James Mullahoo, Jonathan Li, Miriam Adam, Brook Wassie, Moqing Liu, David F. Kilburn, Tiera A. Liby, Elmar Bucher, Crystal Sanchez-Aguila, Kenneth Daily, Larsson Omberg, Yunguan Wang, Connor Jacobson, Clarence Yapp, Mirra Chung, Dusica Vidovic, Yiling Lu, Stephan Schurer, Albert Lee, Ajay Pillai, Aravind Subramanian, Malvina Papanastasiou, Ernest Fraenkel, Heidi S. Feiler, Gordon B. Mills, Jake D. Jaffe, Avi Ma’ayan, Marc R. Birtwistle, Peter K. Sorger, James E. Korkola, Joe W. Gray, Laura M. Heiser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)
Comprehensive profiling of ligand-induced perturbation responses of the MCF10A mammary epithelial cell line provides an exhaustive resource for identification of the molecular basis of cellular phenotypes.
Externí odkaz:
https://doaj.org/article/50400b000ed946209179e826cd85298c
Autor:
Evan Austin, Eugene Koo, Alexander Merleev, Denis Torre, Alina Marusina, Guillaume Luxardi, Andrew Mamalis, Roslyn Rivkah Isseroff, Avi Ma’ayan, Emanual Maverakis, Jared Jagdeo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Fibrosis occurs when collagen deposition and fibroblast proliferation replace healthy tissue. Red light (RL) may improve skin fibrosis via photobiomodulation, the process by which photosensitive chromophores in cells absorb visible or near-i
Externí odkaz:
https://doaj.org/article/1a227c143dba4b9495dc0bf4c116257c
Autor:
Maria Gonzalez-Perez, Maria Montes-Casado, Patricia Conde, Isabel Cervera, Jana Baranda, Marcos J. Berges-Buxeda, Mayte Perez-Olmeda, Rodrigo Sanchez-Tarjuelo, Alberto Utrero-Rico, Daniel Lozano-Ojalvo, Denis Torre, Megan Schwarz, Ernesto Guccione, Carmen Camara, M Rosario Llópez-Carratalá, Emilio Gonzalez-Parra, Pilar Portoles, Alberto Ortiz, Jose Portoles, Jordi Ochando
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Long-term hemodialysis (HD) patients are considered vulnerable and at high-risk of developing severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection due to their immunocompromised condition. Since COVID-19 associated mortality ra
Externí odkaz:
https://doaj.org/article/c2a0685e3ae0484b8419bbf67f155dca
Autor:
Slim Mzoughi, Jia Yi Fong, David Papadopoli, Cheryl M. Koh, Laura Hulea, Paolo Pigini, Federico Di Tullio, Giuseppe Andreacchio, Michal Marek Hoppe, Heike Wollmann, Diana Low, Matias J. Caldez, Yanfen Peng, Denis Torre, Julia N. Zhao, Oro Uchenunu, Gabriele Varano, Corina-Mihaela Motofeanu, Manikandan Lakshmanan, Shun Xie Teo, Cheng Mun Wun, Giovanni Perini, Soo Yong Tan, Chee Bing Ong, Muthafar Al-Haddawi, Ravisankar Rajarethinam, Susan Swee-Shan Hue, Soon Thye Lim, Choon Kiat Ong, Dachuan Huang, Siok-Bian Ng, Emily Bernstein, Dan Hasson, Keng Boon Wee, Philipp Kaldis, Anand Jeyasekharan, David Dominguez-sola, Ivan Topisirovic, Ernesto Guccione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The transcriptional regulator PRDM15 is expressed at low levels in normal tissues but overexpressed in B-cell lymphomas. Here, the authors show that PRDM15 depletion does not affect adult somatic cell homeostasis but leads to a metabolic crisis which
Externí odkaz:
https://doaj.org/article/9df5fd5400ec47e98903d3b9c0b42cbb
Autor:
Alexander Lachmann, Denis Torre, Alexandra B. Keenan, Kathleen M. Jagodnik, Hoyjin J. Lee, Lily Wang, Moshe C. Silverstein, Avi Ma’ayan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Publicly available RNA-seq data is provided mostly in raw form, resulting in a barrier for integrative analyses. Here, Lachmann et al. develop a high-throughput processing infrastructure and search database (ARCHS4) that provides processed RNA-seq da
Externí odkaz:
https://doaj.org/article/a4b3aba2b6f14c43a70efb62e5746283
Autor:
Laura Campisi, Shahab Chizari, Jessica S. Y. Ho, Anastasia Gromova, Frederick J. Arnold, Lorena Mosca, Xueyan Mei, Yesai Fstkchyan, Denis Torre, Cindy Beharry, Marta Garcia-Forn, Miguel Jiménez-Alcázar, Vladislav A. Korobeynikov, Jack Prazich, Zahi A. Fayad, Marcus M. Seldin, Silvia De Rubeis, Craig L. Bennett, Lyle W. Ostrow, Christian Lunetta, Massimo Squatrito, Minji Byun, Neil A. Shneider, Ning Jiang, Albert R. La Spada, Ivan Marazzi
Publikováno v:
Nature, vol 606, iss 7916
Nature
Nature
Amyotrophic lateral sclerosis (ALS) is a heterogenous neurodegenerative disorder that affects motor neurons and voluntary muscle control1. ALS heterogeneity includes the age of manifestation, the rate of progression and the anatomical sites of sympto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3cef62b703bbd573ed47465237ff1b
https://doi.org/10.1038/s41586-022-04844-5
https://doi.org/10.1038/s41586-022-04844-5
Autor:
Jemima E. Mellerio, Ellie Rashidghamat, John A. McGrath, Avi Ma'ayan, Laura E. Proudfoot, Tuntas Rayinda, Denis Torre, Alexandros Onoufriadis, Chrysanthi Ainali, Retno Danarti, Maria Papanikolaou
Publikováno v:
Experimental Dermatology. 31:420-426
Chronic wounds present a major disease burden in people with recessive dystrophic epidermolysis bullosa (RDEB), an inherited blistering skin disorder caused by mutations in COL7A1 encoding type VII collagen, the major component of anchoring fibrils a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a629d71b37cd0d21909155a3742412cc
https://doi.org/10.1111/exd.14481
https://doi.org/10.1111/exd.14481
Autor:
Edmund Charles Jenkins, Mrittika Chattopadhyay, Maria Gomez, Denis Torre, Avi Ma'ayan, Miguel Torres‐Martin, Daniela Sia, Doris Germain
Publikováno v:
Aging Cell. 21
A major limitation in the use of mouse models in breast cancer research is that most mice develop estrogen receptor-alpha (ERα)-negative mammary tumors, while in humans, the majority of breast cancers are ERα-positive. Therefore, developing mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0544cc41da6d7c28bd0d5427ada00251
https://doi.org/10.1111/acel.13665
https://doi.org/10.1111/acel.13665
Autor:
John Erol Evangelista, Janice Yang, Alexander Lachmann, Avi Ma'ayan, Zhuorui Xie, Ingrid Shu, Alexandra B K London, Maxim V. Kuleshov, Denis Torre
Publikováno v:
Nucleic Acids Research
Phosphoproteomics and proteomics experiments capture a global snapshot of the cellular signaling network, but these methods do not directly measure kinase state. Kinase Enrichment Analysis 3 (KEA3) is a webserver application that infers overrepresent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12266c0305dfab3ec493b5bb1f244796
https://doi.org/10.1093/nar/gkab359
https://doi.org/10.1093/nar/gkab359