Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Denis Seraphin"'
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Akademický článek
A vitamin E long-chain metabolite and the inspired drug candidate α-amplexichromanol relieve asthma features in an experimental model of allergen sensitization
Autor: Ida Cerqua, Konstantin Neukirch, Michela Terlizzi, Elisabetta Granato, Elisabetta Caiazzo, Carla Cicala, Armando Ialenti, Raffaele Capasso, Oliver Werz, Rosalinda Sorrentino, Denis Seraphin, Jean-Jacques Helesbeux, Giuseppe Cirino, Andreas Koeberle, Fiorentina Roviezzo, Antonietta Rossi
Publikováno v: Pharmacological Research, Vol 181, Iss , Pp 106250- (2022)
Benefits for vitamin E intake in diseases with inflammatory components have been described and related in part, to endogenously formed metabolites (long-chain metabolites, LCM). Here, we have evaluated the role of LCM in relieving asthma features. To
Externí odkaz: https://doaj.org/article/cde91b43354b4b5a972cc24aaddca0c7
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4
Novel Cytotoxic 4-Phenylfuranocoumarins from Calophyllum dispar
Autor: Thierry Sevenet, Denis Seraphin, Jean-Jacques Helesbeux, J. Bruneton, David Guilet, Pascal Richomme
Publikováno v: Journal of Natural Products. 64:563-568
Eight new 4-phenylfuranocoumarins (1-8) have been isolated from the stem bark and the fruits of Calophyllum dispar, together with three known coumarins. The structures of 1-8 were established by means of spectroscopic analysis, including extensive 2D
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfbd8e9a0e1574c9e0b82e839fff8b4
https://doi.org/10.1021/np000517o
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5
New Xanthones from Calophyllum caledonicum
Autor: Thierry Sevenet, Pascal Richomme, Cécile Morel, Denis Seraphin, Marc Litaudon, J. Bruneton, J.-M. Oger
Publikováno v: Journal of Natural Products. 63:1471-1474
Four new xanthones, caledonixanthones A-D (1-4), were isolated from the trunk bark of Calophyllum caledonicum, in addition to 17 known compounds. The structures of 1-4 were determined by means of spectroscopic analysis and chemical derivatization.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e47e112420e84ddf1af6f35e16aa82
https://doi.org/10.1021/np000215m
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6
Synthesis of the new (cyclopenta [b]pyrrolo[1,2-d])azepino[4,5-b]indole ring system
Autor: Jacques Henin, Frédéric Djaté, Denis Seraphin, Jean Lévy, Jean-Yves Laronze, Qiang Zhang, Eric Noé
Publikováno v: Tetrahedron Letters. 37:5701-5704
The 2-oxo functionalized title compound 1 was synthesised in 7 steps from tryptamine via rearrangement of the bromoiminium ion 13 in alkaline medium to azepinone 14 with concomitant formation of ketone 15. The ratio 14:15 was shown to depend on the n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad9c806ddb9c3269c4d5247d92df8ff8
https://doi.org/10.1016/0040-4039(96)01215-4
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7
Identification of coumarins in DCM bark, leaf and fruit extracts from Mammea neurophylla (Calophyllaceae) by LC-PDA-MSn
Autor: AM Leray, Séverine Derbré, David Guilet, Denis Seraphin, BT Dang, Pascal Richomme, Ingrid Freuze
Publikováno v: International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF
International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF, 2012, New-York, United States. Planta Medica, 78 (11), p. 1260, 2012, ⟨10.1055/s-0032-1321213⟩
International audience; 4-phenyl and 4-propylcoumarins display a wide variety of biological activities including anti-oxidant and anti-inflammatory effects, antiparasitical activities against Leishmania or Plasmodium as well as antibacterial, antivir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdd6436b956547c9366d38876629e2c
https://hal.univ-angers.fr/hal-03247438
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8
Approaches towards indolic analogues of cephalotaxine via a spiro-cyclohexene strategy
Autor: J.-Y. Laronze, Dominique Cartier, Christine Gauvin-Hussenet, Jean Lévy, Denis Seraphin
Publikováno v: Tetrahedron Letters. 34:465-468
Highly functionalized (dialkyloxo)indoloazepines 10 , 11 , 34 and the pyrroloazepinoindole 35 were prepared via oxidative cleavage of the corresponding spiro-cyclohexene derivative. Tetracycle 35 bears carbons and functionalities required for buildin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::694216aaeb6aa365a2fcb075527f3637
https://doi.org/10.1016/0040-4039(93)85103-4
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ChemInform Abstract: Synthesis of the New (Cyclopenta(b)pyrrolo(1,2-d))azepino(4,5-b)indole Ring System
Autor: Jacques Henin, Jean Lévy, Qiang Zhang, Frédéric Djaté, Denis Seraphin, Eric Noé, Jean-Yves Laronze
Publikováno v: ChemInform. 27
The 2-oxo functionalized title compound 1 was synthesised in 7 steps from tryptamine via rearrangement of the bromoiminium ion 13 in alkaline medium to azepinone 14 with concomitant formation of ketone 15. The ratio 14:15 was shown to depend on the n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b18469d3295428c25675045594e9af3
https://doi.org/10.1002/chin.199646188
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