Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Denis Schapiro"'
Autor:
Geethika Arekatla, Stavroula Skylaki, David Corredor Suarez, Hartland Jackson, Denis Schapiro, Stefanie Engler, Markus Auler, German Camargo Ortega, Simon Hastreiter, Andreas Reimann, Dirk Loeffler, Bernd Bodenmiller, Timm Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pluripotent mouse embryonic stem cells (ESCs) can differentiate to all germ layers and serve as an in vitro model of embryonic development. To better understand the differentiation paths traversed by ESCs committing to different lineages, we
Externí odkaz:
https://doaj.org/article/b8a1252720554a2e99b83d10ecd90a0e
Autor:
Jovan Tanevski, Ricardo Omar Ramirez Flores, Attila Gabor, Denis Schapiro, Julio Saez-Rodriguez
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract The advancement of highly multiplexed spatial technologies requires scalable methods that can leverage spatial information. We present MISTy, a flexible, scalable, and explainable machine learning framework for extracting relationships from
Externí odkaz:
https://doaj.org/article/98808e26af9748a883ca51a1aae8c3b1
Autor:
Sanja Vickovic, Denis Schapiro, Konstantin Carlberg, Britta Lötstedt, Ludvig Larsson, Franziska Hildebrandt, Marina Korotkova, Aase H. Hensvold, Anca I. Catrina, Peter K. Sorger, Vivianne Malmström, Aviv Regev, Patrik L. Ståhl
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Sanja Vickovic et al. use spatial transcriptomics to probe the local synovial tissue interactions in rheumatoid arthritis (RA) patients. Their results provide a valuable resource to understand the spatial organisation of cell populations in the synov
Externí odkaz:
https://doaj.org/article/9aa2cc593d9f4b808a9549f5788c0058
Autor:
Anniina Färkkilä, Doga C. Gulhan, Julia Casado, Connor A. Jacobson, Huy Nguyen, Bose Kochupurakkal, Zoltan Maliga, Clarence Yapp, Yu-An Chen, Denis Schapiro, Yinghui Zhou, Julie R. Graham, Bruce J. Dezube, Pamela Munster, Sandro Santagata, Elizabeth Garcia, Scott Rodig, Ana Lako, Dipanjan Chowdhury, Geoffrey I. Shapiro, Ursula A. Matulonis, Peter J. Park, Sampsa Hautaniemi, Peter K. Sorger, Elizabeth M. Swisher, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
A Phase I/II trial previously revealed variable anti-tumor efficacy of the PARP inhibitor niraparib in combination with the PD-1 inhibitor pembrolizumab in platinum-resistant ovarian cancer patients. Here, the authors perform an integrated genomic an
Externí odkaz:
https://doaj.org/article/bd4459e944254dc4845c521cfcab9cf4
Autor:
Fanny A. Pelissier Vatter, Denis Schapiro, Hang Chang, Alexander D. Borowsky, Jonathan K. Lee, Bahram Parvin, Martha R. Stampfer, Mark A. LaBarge, Bernd Bodenmiller, James B. Lorens
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1205-1219 (2018)
Summary: Aging is associated with tissue-level changes in cellular composition that are correlated with increased susceptibility to disease. Aging human mammary tissue shows skewed progenitor cell potency, resulting in diminished tumor-suppressive ce
Externí odkaz:
https://doaj.org/article/22da90f3a5494c2792bf90da14d96c6c
Modeling Cell-Cell Interactions from Spatial Molecular Data with Spatial Variance Component Analysis
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 202-211.e6 (2019)
Summary: Technological advances enable assaying multiplexed spatially resolved RNA and protein expression profiling of individual cells, thereby capturing molecular variations in physiological contexts. While these methods are increasingly accessible
Externí odkaz:
https://doaj.org/article/94ef3d629dfb4fcf85c6531a7db09383
Autor:
Anniina Färkkilä, Doga C. Gulhan, Julia Casado, Connor A. Jacobson, Huy Nguyen, Bose Kochupurakkal, Zoltan Maliga, Clarence Yapp, Yu-An Chen, Denis Schapiro, Yinghui Zhou, Julie R. Graham, Bruce J. Dezube, Pamela Munster, Sandro Santagata, Elizabeth Garcia, Scott Rodig, Ana Lako, Dipanjan Chowdhury, Geoffrey I. Shapiro, Ursula A. Matulonis, Peter J. Park, Sampsa Hautaniemi, Peter K. Sorger, Elizabeth M. Swisher, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/7abeb069106949588957c1f409b64b58
Autor:
Gunnar Schwarz, Hao A. O. Wang, Charlotte Giessen, Denis Schapiro, Bodo Hattendorf, Bernd Bodenmiller, Detlef Günther
Publikováno v:
CHIMIA, Vol 69, Iss 10 (2015)
Externí odkaz:
https://doaj.org/article/4fd854d005754def907829c968f294cd
Funder: Royal Swedish Academy of Sciences (Kungl. Vetenskapsakademien); doi: https://doi.org/10.13039/501100001725
Funder: Svenska Läkaresällskapet (Swedish Society of Medicine); doi: https://doi.org/10.13039/501100007687
Funder: KMB Foun
Funder: Svenska Läkaresällskapet (Swedish Society of Medicine); doi: https://doi.org/10.13039/501100007687
Funder: KMB Foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8ef80f2dda676a0c0800162a8969a8
https://www.repository.cam.ac.uk/handle/1810/347364
https://www.repository.cam.ac.uk/handle/1810/347364
Autor:
Celia Lerma-Martin, Pau Badia-i-Mompel, Ricardo O. Ramirez Flores, Patricia Sekol, Annika Hofmann, Thomas Thäwel, Christian J. Riedl, Florian Wünnemann, Miguel A. Ibarra-Arellano, Tim Trobisch, Philipp Eisele, Denis Schapiro, Maximilian Haeussler, Simon Hametner, Julio Saez-Rodriguez, Lucas Schirmer
Multiple sclerosis (MS) is a prototypic chronic-inflammatory disease of the central nervous system. After initial lesion formation during active demyelination, inflammation is gradually compartmentalized and restricted to specific tissue areas such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f11b1146c16cff385def94c52c8b78cf
https://doi.org/10.1101/2022.11.03.514906
https://doi.org/10.1101/2022.11.03.514906