Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Denis S. Loiselle"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
In the excitation of muscle contraction, calcium ions interact with transmembrane transporters. This process is accompanied by energy consumption and heat liberation. To quantify this activation energy or heat in the heart or cardiac muscle, two non-
Externí odkaz:
https://doaj.org/article/0ff2444b2cf3474f840e38f2992e21d8
Autor:
Megan E. Guidry, David P. Nickerson, Edmund J. Crampin, Martyn P. Nash, Denis S. Loiselle, Kenneth Tran
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
In experimental studies on cardiac tissue, the end-systolic force-length relation (ESFLR) has been shown to depend on the mode of contraction: isometric or isotonic. The isometric ESFLR is derived from isometric contractions spanning a range of muscl
Externí odkaz:
https://doaj.org/article/ccb06e400f27479dae91ce666348e9cd
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
We have recently demonstrated the existence of a region on the cardiac mechanics stress-length plane, which we have designated “The cardiac end-systolic zone.” The zone is defined as the area on the pressure-volume (or stress-length) plane within
Externí odkaz:
https://doaj.org/article/90ea6b878e0149ceb69982d82c4ca0ef
Autor:
June-Chiew Han, Sarah-Jane Guild, Toan Pham, Linley Nisbet, Kenneth Tran, Andrew J. Taberner, Denis S. Loiselle
Publikováno v:
Frontiers in Physiology, Vol 8 (2018)
Pulmonary arterial hypertension (PAH) alters the geometries of both ventricles of the heart. While the right ventricle (RV) hypertrophies, the left ventricle (LV) atrophies. Multiple lines of clinical and experimental evidence lead us to hypothesize
Externí odkaz:
https://doaj.org/article/dbbbb0ebf09c41bd9d9139fe80f1d732
Right-sided heart failure is also associated with transverse tubule remodeling in the left ventricle
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H940-H947
In this work, we demonstrate that t-tubule remodeling occurs in the atrophied left ventricle as well as the overloaded right ventricle after right-side heart failure. Moreover, we identify that t-tubule remodeling in both ventricles is linked to sarc
Publikováno v:
Progress in Biophysics and Molecular Biology. 164:81-91
The theory proposed by Suga and Sagawa, encompassing the concepts of ‘time-varying elastance’, ‘pressure-volume area’ and ‘isoefficiency’, has been widely applied in cardiac research - albeit not without contention. In this Review, we com
Publikováno v:
Progress in Biophysics and Molecular Biology. 161:3-16
The objective of this article is to provide an historical perspective on a review of "Heat production and chemical change in muscle" written by Roger C. Woledge and published in Progress in Biophysics and Molecular Biology 50 years ago. We first prov
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(3)
Conventional experimental methods for studying cardiac muscle in vitro often do not expose the tissue preparations to a mechanical impedance that resembles the in vivo hemodynamic impedance dictated by the arterial system. That is, the afterload in w
Publikováno v:
The Journal of physiologyReferences. 600(19)
The formulation by Starling of The Law of the Heart states that 'the [mechanical] energy of contraction, however measured, is a function of the length of the muscle fibre'. Starling later also stated that 'the oxygen consumption of the isolated heart
Autor:
Brian Chapman, Denis S. Loiselle
Publikováno v:
Photochemical & Photobiological Sciences. 19:1623-1629
Neither the thermodynamically determined probability isotherm nor its kinetically manifest rate isotherm can be applied to photo-absorptive reactions such that the participants, including photons, may be treated as if they were chemical reactants. Ph