Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Denis Séraphin"'
Autor:
Gabriele Möller, Veronika Temml, Antonio Cala Peralta, Océane Gruet, Pascal Richomme, Denis Séraphin, Guillaume Viault, Luisa Kraus, Petra Huber-Cantonati, Elisabeth Schopfhauser, Johanna Pachmayr, Janina Tokarz, Daniela Schuster, Jean-Jacques Helesbeux, Kenneth Allen Dyar
Publikováno v:
Metabolites, Vol 12, Iss 2, p 99 (2022)
Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and prel
Externí odkaz:
https://doaj.org/article/2ab68851bb2c41d1830b279e836dcadf
Autor:
Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Vitamin E metabolites are proposed to have signalling capacity, but how they may regulate immune responses is still unclear. Here the authors show that a vitamin E metabolite, α-T-13′-COOH, can inhibit 5-lipoxygenase and thereby suppress the synth
Externí odkaz:
https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5
Autor:
Bach Tai Dang, Caroline Rouger, Marc Litaudon, Pascal Richomme, Denis Séraphin, Séverine Derbré
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 17735-17746 (2015)
Through dereplication analysis, seven known Mammea coumarins were identified in a fraction obtained from Mammea neurophylla dichloromethane bark extract selected for its ability to prevent advanced glycation end-product (AGE) formation. Among them, a
Externí odkaz:
https://doaj.org/article/126032d2fc7c47cb932d7dea2fd5d926
Autor:
Luc Séro, Lionel Sanguinet, Patricia Blanchard, Bach Tai Dang, Sylvie Morel, Pascal Richomme, Denis Séraphin, Séverine Derbré
Publikováno v:
Molecules, Vol 18, Iss 11, Pp 14320-14339 (2013)
Advanced glycation end-products (AGEs) are involved in the pathogenesis of numerous diseases. Among them, cellular accumulation of AGEs contributes to vascular complications in diabetes. Besides using drugs to lower blood sugar, a balanced diet and t
Externí odkaz:
https://doaj.org/article/24c63052d3da4bed9534b7dc2901bd3c
Autor:
Denis Séraphin, Pascal Richomme, Eric Levillain, Jean-Jacques Helesbeux, Marylène Dias, Séverine Derbré, Kamal Elouarzaki, Suresh Babu, Andreas Schinkovitz, Ghislain Tsague Kenfack
Publikováno v:
Molecules, Vol 16, Iss 10, Pp 8758-8774 (2011)
The synthesis of five light absorbing triazolobithiophenic thiols, which were utilized for producing self-assembled monolayers (SAMs) on gold surfaces, is presented. The monolayer formation was monitored by cyclic voltammetry, indicating excellent su
Externí odkaz:
https://doaj.org/article/037364cc2e7643b59301a6d956f69215
Autor:
Mickaël Lecomte, Latifa Hamama, Linda Voisine, Julia Gatto, Jean-Jacques Hélesbeux, Denis Séraphin, Luis M Peña-Rodriguez, Pascal Richomme, Cora Boedo, Claire Yovanopoulos, Melvina Gyomlai, Mathilde Briard, Philippe Simoneau, Pascal Poupard, Romain Berruyer
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101008 (2014)
Although different mechanisms have been proposed in the recent years, plant pathogen partial resistance is still poorly understood. Components of the chemical warfare, including the production of plant defense compounds and plant resistance to pathog
Externí odkaz:
https://doaj.org/article/894a4fabd6124420998b12e8683599e1
Autor:
Rodolphe Perrot, Jean-Jacques Helesbeux, Denis Séraphin, Marie Kempf, Pascal Richomme, Khaled Alsabil, Guillaume Viault, Alexia Ville
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
New 5-substituted vitamin E derivatives were semisynthesized, and their antibacterial activity against human Gram-positive and Gram-negative pathogens was evaluated. Several vitamin E analogues were active against methicillin-resistant Staphylococcus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490659c4c8c7aed149cab7177434bb72
https://doi.org/10.1002/cmdc.202000792
https://doi.org/10.1002/cmdc.202000792
Autor:
Jimmy Josué Ceballos-Cruz, Jean-Jacques Hélesbeux, Guillaume Viault, Denis Séraphin, Gumersindo Mirón-López, Rubén M. Carballo, Pascal Richomme, Luis Manuel Peña-Rodríguez
Publikováno v:
Journal of the Mexican Chemical Society. 66
Chalcone-vitamin E hybrids 6’-O-tosyl-3,4,5-trimethoxy-δ-tocopherol-chalcone (1), 3,4,5-trimethoxy-δ-tocopherol-chalcone (2), 6’-O-tosyl-3,4,5-trimethoxy-δ-tocopherol-retrochalcone (3) and 3,4,5-trimethoxy-δ-tocopherol-retrochalcone (4) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7251a2f3e2ad9290a013a26a385b33ff
https://doi.org/10.29356/jmcs.v66i1.1670
https://doi.org/10.29356/jmcs.v66i1.1670
Autor:
Denis Séraphin, Christian Kretzer, Markus Werner, Pascal Richomme, Andreas Koeberle, Veronika Temml, Paul M. Jordan, Jean-Jacques Helesbeux, Daniela Schuster, Katharina P.L. Meyer, Robert Klaus Hofstetter, Guillaume Viault, Antonio Cala Peralta, Hermann Stuppner, Daniel Hoff, Oliver Werz
Publikováno v:
Biochemical pharmacology. 195
Specialized pro-resolving mediators (SPMs) comprise lipid mediators (LMs) produced from polyunsaturated fatty acids (PUFAs) via stereoselective oxygenation particularly involving 12/15-lipoxygenases (LOXs). In contrast to pro-inflammatory LMs such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8baf0cc99b4fbc5fbcb7fd425e09c4
https://pubmed.ncbi.nlm.nih.gov/34762841
https://pubmed.ncbi.nlm.nih.gov/34762841
Autor:
Andreas Koeberle, Denis Séraphin, Stefan Lorkowski, Tiago Rodrigues, Oliver Werz, Daniela Schuster, Dimitri Bréard, Hermann Stuppner, Ida Cerqua, Antonietta Rossi, Simona Pace, Marta C. Marques, Alexander S. Mosig, Paul M. Jordan, Stephan Permann, Jana Gerstmeier, Martin Raasch, Gonçalo J. L. Bernardes, André Gollowitzer, Ulrike Garscha, Chau-Phi Dinh, Alexia Ville, Jean-Jacques Helesbeux, Fiorentina Roviezzo, Guillaume Viault, Elena Brunner, Pascal Richomme, Veronika Temml, Rossella Bilancia, Khaled Alsabil, Konstantin Loeser, Konstantin Neukirch
Publikováno v:
Journal of Medicinal Chemistry
Endogenous long-chain metabolites of vitamin E (LCMs) mediate immune functions by targeting 5-lipoxygenase (5-LOX) and increasing the systemic concentrations of resolvin E3, a specialized proresolving lipid mediator. SAR studies on semisynthesized an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197aa94407387a7b89fbecdcc110c28a
http://hdl.handle.net/11588/879642
http://hdl.handle.net/11588/879642
