Výsledky vyhledávání

Akademický článek

BCG downregulates PD1 and PD-L1 expression in bladder cancer cells co-cultivated with peripheral blood mononuclear cells

Autor: Katia R. M. Leite, Denis Reis Morais, Cristina Massoco, Sabrina T. Reis, Nayara I. Viana, Iran A. Silva, Vanessa Guimaraes, Ruan Pimenta, Gabriel Arantes, Miguel Srougi, Willian Carlos Nahas

Publikováno v: Surgical and Experimental Pathology, Vol 5, Iss 1, Pp 1-5 (2022)

Abstract Purpose BCG is the standard of care to treat high risk non-muscle invasive bladder cancer (NMIBC), reducing recurrence. PD-L1 is a ligand of the co-inhibitory receptor PD1 that has been shown to be expressed by tumor cells of distinct origin

Externí odkaz: https://doaj.org/article/eb4bd3001dcf448a9dfbf64bd51ead04

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Akademický článek

Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics

Autor: Rita de Cássia Oliveira, Renato Fidelis Ivanovic, Katia Ramos Moreira Leite, Nayara Izabel Viana, Ruan César Aparecido Pimenta, José Pontes Junior, Vanessa Ribeiro Guimarães, Denis Reis Morais, Daniel Kanda Abe, Adriano João Nesrallah, Miguel Srougi, William Nahas, Sabrina Thalita Reis

Publikováno v: BMC Urology, Vol 17, Iss 1, Pp 1-8 (2017)

Abstract Background Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer in adults. Our aim is to evaluate genes and miRNAs expression profiles involved with angiogenesis and tumor characteristics in ccRCC. Methods The e

Externí odkaz: https://doaj.org/article/7684a618c3df402288f288e229817ad5

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Akademický článek

Metabolomics Biomarkers: A Strategy Toward Therapeutics Improvement in ALS

Autor: Débora Lanznaster, Denis Reis de Assis, Philippe Corcia, Pierre-François Pradat, Hélène Blasco

Publikováno v: Frontiers in Neurology, Vol 9 (2018)

Biomarkers research in amyotrophic lateral sclerosis (ALS) holds the promise of improving ALS diagnosis, follow-up of patients, and clinical trials outcomes. Metabolomics have a big impact on biomarkers identification. In this mini-review, we provide

Externí odkaz: https://doaj.org/article/8911e63f16414e439c121ebd5fa2bf68

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Akademický článek

Using iPSC Models to Understand the Role of Estrogen in Neuron–Glia Interactions in Schizophrenia and Bipolar Disorder

Autor: Denis Reis de Assis, Attila Szabo, Jordi Requena Osete, Francesca Puppo, Kevin S. O’Connell, Ibrahim A. Akkouh, Timothy Hughes, Evgeniia Frei, Ole A. Andreassen, Srdjan Djurovic

Publikováno v: Cells, Vol 10, Iss 2, p 209 (2021)

Schizophrenia (SCZ) and bipolar disorder (BIP) are severe mental disorders with a considerable disease burden worldwide due to early age of onset, chronicity, and lack of efficient treatments or prevention strategies. Whilst our current knowledge is

Externí odkaz: https://doaj.org/article/43df122af6e3483db6201c3ed8820e33

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Akademický článek

Underexpression of MMP-2 and its regulators, TIMP2, MT1-MMP and IL-8, is associated with prostate cancer

Autor: Sabrina Thalita Reis, Alberto Azoubel Antunes, Jose Pontes-Junior, Juliana Moreira de Sousa-Canavez, Marcos Francisco Dall'Oglio, Camila Belfort Piantino, Jose Arnaldo Shiomi da Cruz, Denis Reis Morais, Miguel Srougi, Katia R. M. Leite

Publikováno v: International Brazilian Journal of Urology, Vol 38, Iss 2, Pp 167-174 (2012)

OBJECTIVE: Extracellular matrix homeostasis is strictly maintained by a coordinated balance between the expression of metalloproteinases (MMPs) and their regulators. The purpose of this study was to investigate whether MMP-2 and its specific regulato

Externí odkaz: https://doaj.org/article/bd468c2f4cf24e66a34e102d06e803d6

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Dissertation/ Thesis

O papel do miR-100 na proliferação, indução da apoptose e instabilidade cromossômica em linhagens celulares de câncer de bexiga e próstata

Autor: Denis Reis Morais

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

Introdução: O câncer de próstata (CaP) é o tumor sólido mais diagnosticado no homem atualmente, e a sexta ocorrência mais frequente de casos novos de neoplasia maligna no mundo, sendo a segunda causa de óbito por câncer. O câncer de bexiga

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/5/5153/tde-08112013-112945/

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