Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Denis Raymond Christophe Bouvet"'
Autor:
Mark Battle, Alessandra Gaeta, Dennis O'shea, Penny Hao Zheng, Julian Goggi, Stuart Plant, Benedicte Guilbert, Samantha L. Brown, Amanda Ewan, Paul A. Jones, John Woodcraft, Alexander Jackson, Denis Raymond Christophe Bouvet, William Trigg, Clare Jones
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:821-826
Positron emission tomography (PET) using the tracer [(11)C]Flumazenil has shown changes in the distribution and expression of the GABA(A) receptor in a range of neurological conditions and injury states. We aim to develop a fluorine-18 labelled PET a
Autor:
Dennis O'shea, Mark Battle, Wai-Fung Chau, William Trigg, Samantha L. Brown, Alexander Jackson, Paul A. Jones, Amanda Ewan, Alessandra Gaeta, Denis Raymond Christophe Bouvet, Benedicte Guilbert, Clare Jones, John Woodcraft
Publikováno v:
Nuclear medicine and biology. 41(2)
Introduction [ 11 C]Flumazenil has been used to study the GABA A receptor in many preclinical and clinical studies, but the short half-life of carbon-11 means that this molecule is restricted to use by investigators with access to on-site cyclotron a
Autor:
Denis Raymond Christophe Bouvet, Harry John Wadsworth, Richard C. D. Brown, Nicolas Millot, Amy C. Topley, Lynda J. Brown, Duncan Wynn, Imtiaz Khan, Alex Gibson, Alex Jackson, Nianchun Ma, Susan Champion, Yulai Hu
Publikováno v:
Organicbiomolecular chemistry. 7(3)
A new approach to the synthesis of 2-fluoro-2-deoxy-d-glucose (FDG, [(19/18)F]-) is described, which employs supported perfluoroalkylsulfonate precursors , where the support consists of insoluble polystyrene resin beads. Treatment of these resins wit
Autor:
Yulai Hu, Lynda J. Brown, Denis Raymond Christophe Bouvet, Nianchun Ma, Harry John Wadsworth, Imtiaz Khan, Susan Champion, Richard C. D. Brown, Alex Gibson, Nicholas Millot, Alex Jackson
Publikováno v:
Angewandte Chemie (International ed. in English). 46(6)
Due to the short half-life of [18F] (half-life = 110min), the synthesis and purification ofradiotracers incorporating this positron-emitting radionuclide needs to be carried out as rapidly aspossible for applications in imaging using positron emissio