Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Denis O. Sviridov"'
Autor:
Kianoush Jeiran, Scott M. Gordon, Denis O. Sviridov, Angel M. Aponte, Amanda Haymond, Grzegorz Piszczek, Diego Lucero, Edward B. Neufeld, Iosif I. Vaisman, Lance Liotta, Ancha Baranova, Alan T. Remaley
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11480 (2022)
ApoB-100 is a member of a large lipid transfer protein superfamily and is one of the main apolipoproteins found on low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) particles. Despite its clinical significance for the development
Externí odkaz:
https://doaj.org/article/98e0a25364e14d1aa5df2635a0ee5907
Publikováno v:
Cells, Vol 10, Iss 3, p 597 (2021)
Since the seminal breakthrough of treating diabetic patients with insulin in the 1920s, there has been great interest in developing other proteins and their peptide mimetics as therapies for a wide variety of other medical disorders. Currently, there
Externí odkaz:
https://doaj.org/article/e6a998dff60c4075b28f43e92bddf41a
Autor:
Anna Schwendeman, Denis O. Sviridov, Wenmin Yuan, Yanhong Guo, Emily E. Morin, Yue Yuan, John Stonik, Lita Freeman, Alice Ossoli, Seth Thacker, Salena Killion, Milton Pryor, Y.Eugene Chen, Scott Turner, Alan T. Remaley
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 9, Pp 1727-1737 (2015)
The goal of this study was to understand how the reconstituted HDL (rHDL) phospholipid (PL) composition affects its cholesterol efflux and anti-inflammatory properties. An ApoA-I mimetic peptide, 5A, was combined with either SM or POPC. Both lipid fo
Externí odkaz:
https://doaj.org/article/3aec2a28f5f14616ab6cd25ac3bdcd9f
Autor:
Tony J. Zheng, Tia C. L. Kohs, Paul A. Mueller, Jiaqing Pang, Stéphanie E. Reitsma, Iván Parra-Izquierdo, Alexander R. Melrose, Liping Yang, Jaewoo Choi, Keith D. Zientek, Denis O. Sviridov, Mark K. Larson, Craig D. Williams, Nathalie Pamir, Joseph J. Shatzel, Ashok P. Reddy, Paul Kievit, Alan T. Remaley, Jan F. Stevens, Monica T. Hinds, Owen J. T. McCarty, Joseph E. Aslan
Publikováno v:
Blood Advances. 7:1366-1378
Low-density lipoprotein (LDL) contributes to atherogenesis and cardiovascular disease through interactions with peripheral blood cells, especially platelets. However, mechanisms by which LDL affects platelet activation and atherothrombosis, and how t
Autor:
Wenmin, Yuan, Kelsey, Ernst, Rui, Kuai, Emily E, Morin, Minzhi, Yu, Denis O, Sviridov, Jie, Tang, Ling, Mei, Dan, Li, Rose, Ackermann, Alan T, Remaley, Anna, Schwendeman
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 48:102646
Synthetic high-density lipoproteins nanomedicine (sHDL) composed of apolipoprotein A-I (ApoA-I) mimetic peptides and lipids have shown very promising results for the treatment of various cardiovascular diseases. Numerous efforts have also been made t
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Human Apolipoprotein B-100 (ApoB-100) is the main protein of VLDL and LDL particles in plasma. It is a large 4536 amino acid protein with various structural domains, such as the LDL-receptor binding motif and multiple proteoglycan binding sites, all
Autor:
Edward B Neufeld, Nicolas O Francone, Gizem Yilmaz, Scott M Gordon, Denis O Sviridov, Maureen Sampson, Stephen J Demosky, Milton Pryor, Marcelo J Amar, Alan T Remaley
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
We developed a sensitive and robust in vitro method to monitor lipoprotein cholesterol and protein exchange and lipoprotein remodeling, using non-exchangeable fluorescent phosphatidylethanolamine (PE) as a lipoprotein marker. We applied this method t
Autor:
Denis O Sviridov, Anna A Schwendeman, Gwangseong Kim, John Stonik, Scott Turner, Alan T Remaley
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Introduction 5A (DWLKAFYDKVAEKLKEAF-P-DWAKAAYDKAAEKAKEAA) is an apolipoprotein A-I mimetic peptide that is specific for promoting cholesterol efflux by the ABCA1 transporter and has been shown to reduce atherosclerosis and inflammation in animal mode