Výsledky vyhledávání - "Denis Mathé"

Expression and activation of MMP -2, -3, -9, -14 are induced in rat colon after abdominal X-irradiation

Autor: Denis Mathé, Marc Benderitter, Marie-Catherine Vozenin-Brotons, Marie Vandamme, Carine Strup-Perrot

Publikováno v: Scandinavian journal of gastroenterology
Scandinavian journal of gastroenterology, 2006, 41 (1), pp.60-70. ⟨10.1080/00365520510023963⟩

Objective. Colonic response to single-dose irradiation is characterized by epithelial denudation followed by restitution. Extracellular matrix (ECM) remodeling is involved in both of these phases. The aim of this study was to characterize the contrib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a235955a8c48e5889ba0305ddc553795
https://doi.org/10.1080/00365520510023963

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Induction of CTGF by TGF-β1 in normal and radiation enteritis human smooth muscle cells: Smad/Rho balance and therapeutic perspectives

Autor: Denis Mathé, Jocelyne Aigueperse, Marie-Catherine Vozenin-Brotons, Valérie Haydont, Céline Bourgier, Jalil Abdelali, Jean Bourhis

Publikováno v: Radiotherapy and Oncology. 76:219-225

Background and purpose Transforming Growth Factor β1 (TGF-β1) and its downstream effector Connective Tissue Growth Factor (CTGF/CCN2), are well known fibrogenic activators and we previously showed that the Rho/ROCK pathway controls CTGF expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b56515859549984f1a16e5db4db98df
https://doi.org/10.1016/j.radonc.2005.06.029

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Regulation of the collagen phenotype expression of gamma-irradiated vascular smooth muscle cells by heparan mimetics (RGTA)

Autor: Patricia Mestries, Denis Barritault, Carine Strup, P. Kern, Catherine Alexakis, Denis Mathé, Jean-Pierre Caruelle

Publikováno v: Journal of Biomedical Materials Research Part A. :594-602

Restenosis is characterized by vascular smooth muscle cell (VSMC) proliferation and accumulation of col- lagen III in a hypertrophic and disorganized extracellular matrix. Restenosis is prevented by antimitotic agents or irradiation but no significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::014d1ee3e61d2de4175f3b80527d938a
https://doi.org/10.1002/jbm.a.30119

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Les oxystérols : métabolisme, rôles biologiques et pathologies associées

Autor: Maâmar Souidi, Michel Parquet, Jean-Marc A. Lobaccaro, Jocelyne Aigueperse, Claude Lutton, Pascale Scanff, Olivier Combes, Sandrine Dubrac, Denis Mathé, David H. Volle

Publikováno v: Gastroentérologie Clinique et Biologique. 28:279-293

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe0b2422a75752ea4109646b7f013269
https://doi.org/10.1016/s0399-8320(04)94919-6

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Abdominal irradiation increases inflammatory cytokine expression and activates NF-κB in rat ileal muscularis layer

Autor: Christine Linard, Denis Mathé, A. Ropenga, A. Chapel, Marie-Catherine Vozenin-Brotons

Publikováno v: Scopus-Elsevier

The small bowel is an important dose-limiting organ in abdominal radiotherapy because irradiation can cause acute enteritis that, in turn, leads to progressively reduced motility and finally, in a later phase, to fibrosis. Because these clinical symp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2042234f6660444c563f82f19c3a95c0
https://doi.org/10.1152/ajpgi.00094.2003

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‘In‐field’ and ‘out‐of‐field’ functional impairment during subacute and chronic phases of experimental radiation enteropathy in the rat

Autor: N. M. Griffiths, Denis Mathé, Fabien Milliat, Agnès François, Marie-Catherine Vozenin-Brotons

Publikováno v: International Journal of Radiation Biology
International Journal of Radiation Biology, 2003, 79 (6), pp.437-450. ⟨10.1080/0955300031000150594⟩

Purpose: To investigate subacute and chronic functional consequences of localized irradiation of rat small intestine on exposed and shielded segments (proximal and distal). Materials and methods: The surgical model of a scrotal hernia was used. The i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d7d860f809dc0fe9aebea9c0f2ab28
https://doi.org/10.1080/0955300031000150594

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[Untitled]

Autor: Carine Strup, C. Marquette, Denis Mathé, Jocelyne Aigueperse, Christine Linard

Publikováno v: Digestive Diseases and Sciences. 48:688-697

In this study we analyzed the role of substance P (SP) from afferent nerves in ileum contractibility and in the release of inflammatory mediators (neurotensin, Il-1beta, and TNF-alpha) in ileal mucosa and muscularis layers after a 10-Gy gamma-irradia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::235f56d4f82539635d577fe4fa528fdc
https://doi.org/10.1023/a:1022872322578

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Heparan mimetic regulates collagen expression and TGF‐β1 distribution in gamma‐irradiated human intestinal smooth muscle cells

Autor: Carine Strup, Ahmed Guettoufi, Denis Barritault, Christel Barbaud, Jean-Pierre Caruelle, Denis Mathé, Catherine Alexakis, Patricia Mestries, P. Kern

Publikováno v: The FASEB Journal. 15:1546-1554

Radiation-induced intestinal fibrosis is characterized by collagen accumulation, a process in which TGF-beta1 plays a key role. We analyzed the effects of gamma radiation on collagen expression and TGF-beta1 distribution in human intestinal smooth mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa12bba5494a36db0a8f532b7f0d8994
https://doi.org/10.1096/fj.00-0756com

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Catabolism of HDL1 cholesteryl ester in the rat. Effect of ethinyl estradiol treatment

Autor: Gérard Champarnaud, Catherine Feurgard, Tahar Hajri, Claude Lutton, Colette Sérougne, Jacqueline Férézou, Denis Mathé

Publikováno v: Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie. 322:591-596

The present study was performed in control and ethinyl estradiol-treated rats in order to determine the mechanisms involved in the catabolism of HDL1 cholesteryl ester. Ligand blottings on liver membranes showed that purified HDL1, containing about 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5856bb697ab70f97e9785edb5d6fde
https://doi.org/10.1016/s0764-4469(00)88529-7

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Ionizing radiation alters hepatic cholesterol metabolism and plasma lipoproteins in Syrian hamster

Autor: Claude Lutton, Jocelyne Aigueperse, Patrick Gourmelon, C. Serougne, Denis Mathé, J. Ferezou, C. Feurgard, N. Boehler

Publikováno v: International Journal of Radiation Biology. 75:757-766

The investigation of the effects of ionizing radiation on hepatic cholesterol metabolism and the concentration and composition of plasma lipoproteins in the male Syrian hamster.After sublethal whole-body 60Co gamma-irradiation (8 Gy, 1 Gy/min), plasm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40fcb63a636b9103eb13cf1350cbf2c
https://doi.org/10.1080/095530099140104

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