Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Denis Marchesan"'
Autor:
Mykhaylo Demydchuk, Chris H. Hill, Aiwu Zhou, Gábor Bunkóczi, Penelope E. Stein, Denis Marchesan, Janet E. Deane, Randy J. Read
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Hunter syndrome is a lysosomal storage disease caused by mutations in the enzyme iduronate-2-sulfatase (IDS). Here, the authors present the IDS crystal structure and give mechanistic insights into mutations that cause Hunter syndrome.
Externí odkaz:
https://doaj.org/article/73c38b90598b4907b8cedce5ff4f26cb
Autor:
Lu Li, Pia Stillemark-Billton, Caroline Beck, Pontus Boström, Linda Andersson, Mikael Rutberg, Johanna Ericsson, Björn Magnusson, Denis Marchesan, Anna Ljungberg, Jan Borén, Sven-Olof Olofsson
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 67-77 (2006)
Epigallocatechin gallate (EGCG) increases the formation of cytosolic lipid droplets by a mechanism that is independent of the rate of triglyceride biosynthesis and involves an enhanced fusion between lipid droplets, a process that is crucial for thei
Externí odkaz:
https://doaj.org/article/6af0b078f7824155a0a6fc42ed32232f
Autor:
Mykhaylo, Demydchuk, Chris H, Hill, Aiwu, Zhou, Gábor, Bunkóczi, Penelope E, Stein, Denis, Marchesan, Janet E, Deane, Randy J, Read
Publikováno v:
Nature Communications
Hunter syndrome is a rare but devastating childhood disease caused by mutations in the IDS gene encoding iduronate-2-sulfatase, a crucial enzyme in the lysosomal degradation pathway of dermatan sulfate and heparan sulfate. These complex glycosaminogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::783dd196fd88151f6f342e7638e4f116
https://pubmed.ncbi.nlm.nih.gov/28593992
https://pubmed.ncbi.nlm.nih.gov/28593992
Autor:
Luke Howard, Denis Marchesan, Nicholas W. Morrell, Jay Suntharalingam, Andrew Exley, Werner Seeger, Robert Voswinckel, Markus Hecker, Zhenping Zhu, Susan Stewart, Joanna Pepke-Zaba, Mark Southwood, Ursula Gehling, Elaine Soon, Rafia S. Al-Lamki, Jun Yang, Mark Toshner
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 180:780-787
Severe pulmonary arterial hypertension (PAH) is characterized by the formation of plexiform lesions and concentric intimal fibrosis in small pulmonary arteries. The origin of cells contributing to these vascular lesions is uncertain. Endogenous endot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a06fb321f4228520a41d452994217ac
https://doi.org/10.1164/rccm.200810-1662oc
https://doi.org/10.1164/rccm.200810-1662oc
Autor:
Jan Borén, Linda Andersson, Björn Magnusson, Pontus Boström, Denis Marchesan, Johanna Ericson, Lennart Asp, Mikael Rutberg, Michelle Ruiz, Sven-Olof Olofsson, Peang Huang, Michael A. Frohman
Publikováno v:
Journal of Cell Science. 119:2246-2257
We have previously uncovered roles for phospholipase D (PLD) and an unknown cytosolic protein in the formation of cytosolic lipid droplets using a cell-free system. In this report, PLD1 has been identified as the relevant isoform, and extracellular s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e602746271b3a32acbcfdcf30d595b
https://doi.org/10.1242/jcs.02941
https://doi.org/10.1242/jcs.02941
Autor:
Linda Andersson, Jan Borén, Björn Magnusson, Johanna Ericsson, Lu Li, Anna Ljungberg, Denis Marchesan, Mikael Rutberg, Caroline Beck, Sven-Olof Olofsson, Pia Stillemark-Billton, Pontus Boström
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 67-77 (2006)
Epigallocatechin gallate (EGCG) increases the formation of cytosolic lipid droplets by a mechanism that is independent of the rate of triglyceride biosynthesis and involves an enhanced fusion between lipid droplets, a process that is crucial for thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873027556a98f17eeaef7bcf215e1eda
http://www.sciencedirect.com/science/article/pii/S0022227520336567
http://www.sciencedirect.com/science/article/pii/S0022227520336567
Autor:
Bertrand Llorente, José E. Pérez-Ortín, María Teresa Rodríguez-Manzaneque, Susana Rodríguez-Navarro, Bernard Dujon, Denis Marchesan, Anna Ramne, Genoveva Uber, Enrique Herrero, Per Sunnerhagen
Publikováno v:
Yeast. 19:1261-1276
In order to clarify their physiological functions, we have undertaken a characterization of the three-membered gene families SNZ1-3 and SNO1-3. In media lacking vitamin B(6), SNZ1 and SNO1 were both required for growth in certain conditions, but neit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1554395195c455c4950b82c8e1e61484
https://doi.org/10.1002/yea.916
https://doi.org/10.1002/yea.916
Autor:
Linda Andersson, Mikael Rutberg, Bengt Johansson, Denis Marchesan, Lennart Asp, Sven-Olof Olofsson, Jan Borén, Thomas Larsson
Publikováno v:
The Journal of biological chemistry. 278(29)
We developed a microsome-based, cell-free system that assembles newly formed triglyceride (TG) into spherical lipid droplets. These droplets were recovered in the d ≤ 1.055 g/ml fraction by gradient ultracentrifugation and were similar in size and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203d7e20e45564a9c1f1da74987f149e
https://pubmed.ncbi.nlm.nih.gov/12730229
https://pubmed.ncbi.nlm.nih.gov/12730229
Autor:
Susana, Rodríguez-Navarro, Bertrand, Llorente, María Teresa, Rodríguez-Manzaneque, Anna, Ramne, Genoveva, Uber, Denis, Marchesan, Bernard, Dujon, Enrique, Herrero, Per, Sunnerhagen, José E, Pérez-Ortín
Publikováno v:
Yeast (Chichester, England). 19(14)
In order to clarify their physiological functions, we have undertaken a characterization of the three-membered gene families SNZ1-3 and SNO1-3. In media lacking vitamin B(6), SNZ1 and SNO1 were both required for growth in certain conditions, but neit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa6b2a8ce1f6bc800fedf203f38c5659
https://pubmed.ncbi.nlm.nih.gov/12271461
https://pubmed.ncbi.nlm.nih.gov/12271461