Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Denis Lacombe"'
Autor:
Robbe Saesen, Kevin Depreytere, Karyna Krupianskaya, Joël Langeweg, Julie Verheecke, Denis Lacombe, Isabelle Huys
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Pragmatic clinical trials (PCTs) are designed to reflect how an investigational treatment would be applied in clinical practice. As such, unlike their explanatory counterparts, they measure therapeutic effectiveness and are capabl
Externí odkaz:
https://doaj.org/article/a218a5b2c2b04ec680b36d2b3e80233c
Autor:
Ulrik Ringborg, Anton Berns, Julio E. Celis, Manuel Heitor, Josep Tabernero, Joachim Schüz, Michael Baumann, Rui Henrique, Matti Aapro, Partha Basu, Regina Beets‐Tan, Benjamin Besse, Fátima Cardoso, Fátima Carneiro, Guy vanden Eede, Alexander Eggermont, Stefan Fröhling, Susan Galbraith, Elena Garralda, Douglas Hanahan, Thomas Hofmarcher, Bengt Jönsson, Olli Kallioniemi, Miklós Kásler, Eva Kondorosi, Jan Korbel, Denis Lacombe, José Carlos Machado, José M. Martin‐Moreno, Francoise Meunier, Péter Nagy, Paolo Nuciforo, Simon Oberst, Júlio Oliveiera, Maria Papatriantafyllou, Walter Ricciardi, Alexander Roediger, Bettina Ryll, Richard Schilsky, Grazia Scocca, Raquel Seruca, Marta Soares, Karen Steindorf, Vincenzo Valentini, Emile Voest, Elisabete Weiderpass, Nils Wilking, Amanda Wren, Laurence Zitvogel
Publikováno v:
Molecular Oncology, Vol 15, Iss 10, Pp 2507-2543 (2021)
Key stakeholders from the cancer research continuum met in May 2021 at the European Cancer Research Summit in Porto to discuss priorities and specific action points required for the successful implementation of the European Cancer Mission and Europe'
Externí odkaz:
https://doaj.org/article/c22fda14b4734f739d61271fea281fd6
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: The role of real-world evidence (RWE) in the development of anticancer therapies has been gradually growing over time. Regulators, payers and health technology assessment agencies, spurred by the rise of the precision medicine model, are
Externí odkaz:
https://doaj.org/article/7d3b63e0e7f5486a90a122004a54cbb1
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 47-53 (2021)
Although collaborations between academic institutions and industry have led to important scientific breakthroughs in the discovery stage of the pharmaceutical research and development process, the role of multistakeholder partnerships in the clinical
Externí odkaz:
https://doaj.org/article/0e50312c350e4b0aabbee99c16907899
Autor:
Anton Berns, Ulrik Ringborg, Julio E. Celis, Manuel Heitor, Neil K. Aaronson, Nancy Abou‐Zeid, Hans‐Olov Adami, Kathi Apostolidis, Michael Baumann, Alberto Bardelli, René Bernards, Yvonne Brandberg, Carlos Caldas, Fabien Calvo, Caroline Dive, Angelika Eggert, Alexander Eggermont, Carolina Espina, Frederik Falkenburg, Jérôme Foucaud, Douglas Hanahan, Ulrike Helbig, Bengt Jönsson, Mette Kalager, Sakari Karjalainen, Miklós Kásler, Pamela Kearns, Klas Kärre, Denis Lacombe, Francesco deLorenzo, Françoise Meunier, Gerd Nettekoven, Simon Oberst, Péter Nagy, Thierry Philip, Richard Price, Joachim Schüz, Eric Solary, Peter Strang, Josep Tabernero, Emile Voest
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1589-1615 (2020)
A comprehensive translational cancer research approach focused on personalized and precision medicine, and covering the entire cancer research–care–prevention continuum has the potential to achieve in 2030 a 10‐year cancer‐specific survival f
Externí odkaz:
https://doaj.org/article/938c652480cf4543b4c52b6778cd7da0
Autor:
Anton Berns, Ulrik Ringborg, Alexander Eggermont, Michael Baumann, Fabien Calvo, Angelika Eggert, Carolina Espina, Douglas Hanahan, Denis Lacombe, Francesco deLorenzo, Simon Oberst, Thierry Philip, Joachim Schüz, Josep Tabernero, Julio E. Celis
Publikováno v:
Molecular Oncology, Vol 13, Iss 11, Pp 2301-2304 (2019)
Externí odkaz:
https://doaj.org/article/a6f41418bbb541d992a37aae6563f6b1
Autor:
Denis Lacombe, Jan Bogaerts, Bertrand Tombal, François Maignen, Leeza Osipienko, Richard Sullivan, Vassilis Golfinopoulos
Publikováno v:
Molecular Oncology, Vol 13, Iss 3, Pp 558-566 (2019)
Bringing therapeutic innovation and the latest science to routine patient care, while safeguarding principles of affordability and equality, is a challenging mission in the current complex multi‐stakeholder environment. Precision oncology and new a
Externí odkaz:
https://doaj.org/article/d0634860f32241d288e1e10a6e8363b9
Autor:
Teodora Lalova, Cristina Padeanu, Anastassia Negrouk, Denis Lacombe, Jan Geissler, Ingrid Klingmann, Isabelle Huys
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Objectives: To analyze the current situation of cross-border access to clinical trials in the EU with an overview of stakeholders' real-life experience, and to identify the needs, challenges, and potential for facilitation of cross-border access.Meth
Externí odkaz:
https://doaj.org/article/2dd5faad906f4fb0bc16d47c92df78f8
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Introduction: Today, many initiatives and papers are devoted to clinical trial data (and to a lesser extent sample) sharing. Journal editors, pharmaceutical companies, funding agencies, governmental organizations, regulators, and clinical investigato
Externí odkaz:
https://doaj.org/article/f3375f38311646ac8b8b846fff235858
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundThe current drug development paradigm has been criticized for being too drug-centered and for not adequately focusing on the patients who will eventually be administered the therapeutic interventions it generates. The drug-driven nature of
Externí odkaz:
https://doaj.org/article/b1f2774fe0f643e2b76b2f2d0943e5df