Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Denis Labreque"'
Autor:
Real Denis, Serge Lamothe, Sui Xiong Cai, Ben Tseng, Shailaja Kasibhatla, William Kemnitzer, Denis Labreque, Monica Bubenick, Candace Crogan-Grundy, Giorgio Attardo, Hong Zhang, John Drewe, Henriette Gourdeau, Songchun Jiang
Publikováno v:
Journal of medicinal chemistry. 51(3)
In our continuing effort to discover and develop apoptosis inducing 4-aryl-4H-chromenes as novel anticancer agents, we explored the structure-activity relationship (SAR) of alkyl substituted pyrrole fused at the 7,8-positions. A methyl group substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d358a289b1af4017fe6365932c98c
https://pubmed.ncbi.nlm.nih.gov/18197614
https://pubmed.ncbi.nlm.nih.gov/18197614
Autor:
Richard Storer, Ben Tseng, Denis Labreque, John Drewe, Giorgio Attardo, Shailaja Kasibhatla, Jianghong Zhao, Henriette Gourdeau, Yan Wang, Songchun Jiang, David Y. Bouffard, Rabindra Rej, Real Denis, Hong Zhang, William Kemnitzer, Serge Lamothe, Sui Xiong Cai, Karen Meerovitch, John Herich, Charles Blais, Shaojuan Jia
Publikováno v:
Journal of medicinal chemistry. 47(25)
By applying a novel cell- and caspase-based HTS assay, 2-amino-3-cyano-7-(dimethylamino)-4-(3-methoxy-4,5-methylenedioxyphenyl)-4H-chromene (1a) has been identified as a potent apoptosis inducer. Compound 1a was found to induce nuclear fragmentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b55f712fbfe080e63799b21a712bb8
https://pubmed.ncbi.nlm.nih.gov/15566300
https://pubmed.ncbi.nlm.nih.gov/15566300
Autor:
William Kemnitzer, John Drewe, Songchun Jiang, Hong Zhang, Candace Crogan-Grundy, Denis Labreque, Monica Bubenick, Giorgio Attardo, Real Denis, Serge Lamothe, Henriette Gourdeau, Ben Tseng, Shailaja Kasibhatla, Sui Xiong Cai
Publikováno v:
Journal of Medicinal Chemistry; Jan2008, Vol. 51 Issue 3, p417-423, 7p