Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Denis Khokhrin"'
Publikováno v:
Molecular Genetics, Microbiology and Virology. 25:163-166
DNA polymorphism is an important factor in the interindividual variations in the reactions of patients to the same drugs. In the current study, the polymorphism in the OCT2, GGT1, HO1, and DNASE1 genes were evaluated for the correlation with cisplati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e15f5c0d33b935566944dbe222a195
https://doi.org/10.3103/s089141681004004x
https://doi.org/10.3103/s089141681004004x
Publikováno v:
Russian Journal of Genetics. 44:1241-1245
Distribution of several widespread, extensively studied polymorphic variants of genes of the cytosol glutathione-S-transferase subfamily (GSTA1, GSTM1, GSTM3, GSTP1, and GSTT1) has been studied in samples from Russian populations of European Russia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08bcf347a4974cf71a930bebd24cfc72
https://doi.org/10.1134/s1022795408100153
https://doi.org/10.1134/s1022795408100153
Autor:
James A. Knowles, Emily H. M. Wong, Svetlana A. Limborska, Denis Khokhrin, Anton Valouev, Andrey Khrunin, Oleg V. Evgrafov, Larissa Nichols, John Novembre, Dmitry Pushkarev, Dmitry A. Verbenko
Siberia and Northwestern Russia are home to over 40 culturally and linguistically diverse indigenous ethnic groups, yet genetic variation and histories of peoples from this region are largely uncharacterized. We present deep whole-genome sequencing d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef9a5cfb2bbe0b3e33289fd88ee3fb1
https://doi.org/10.1101/029421
https://doi.org/10.1101/029421
Publikováno v:
Russian Journal of Genetics. 48:764-766
Polymorphism ofglutathione-S-transferase (GSTA1, GSTM1, GSTM3, GSTP1, and GSTT1) and DNA repair (ERCC1, ERCC2, and XRCC1) genes in samples of ovarian cancer patients and healthy women of the Russian ethnic group was studied. A trend in the allele fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2733c502f7c510ac12858b25d9b582b1
https://doi.org/10.1134/s1022795412050110
https://doi.org/10.1134/s1022795412050110
Publikováno v:
Pharmacogenomics. 15(3)
Aim: Cisplatin and its analogs are potent antitumor agents. However, their use is restricted by significant variability in tumor response and toxicity. There is a great need to identify genetic markers to predict the most important adverse events and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1eb104cc2875f62780c5b402198ca5
https://pubmed.ncbi.nlm.nih.gov/24533712
https://pubmed.ncbi.nlm.nih.gov/24533712
Autor:
Yuliya A. Sleptsova, Feodosia Ivanova, Vera Gorbunova, Alexey Moisseev, Denis Khokhrin, Svetlana A. Limborska, Andrey Khrunin
Publikováno v:
Pharmacogenomics. 13(2)
Aim: There is a substantial difference between Asians and Caucasians in their reaction to platinum drugs. To determine whether population-related genomics contribute to differences in patient outcomes, pharmacogenomic relevance of polymorphisms in so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6587e4629140f49d01ad458481be653a
https://pubmed.ncbi.nlm.nih.gov/22188361
https://pubmed.ncbi.nlm.nih.gov/22188361
Autor:
Andres Metspalu, Milan Macek, Samuli Ripatti, Liene Nikitina-Zake, Irina N. Filippova, Veronika Krulisova, Denis Khokhrin, Jan Lubinski, Stefan Schreiber, N. A. Bebyakova, Tõnu Esko, Mari Nelis, Natalia L. Bolotova, Karola Hannele Rehnström, Andre Franke, Janis Klovins, Andrey Khrunin, Svetlana A. Limborska
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58552 (2013)
PLoS ONE, Vol 8, Iss 3, p e58552 (2013)
Several studies examined the fine-scale structure of human genetic variation in Europe. However, the European sets analyzed represent mainly northern, western, central, and southern Europe. Here, we report an analysis of approximately 166,000 single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048aeb57f9cc8a22f33b13b0408dab3d