Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Denis J. Reen"'
Autor:
Denis J. Reen, Mark J. McCarron
Publikováno v:
The Journal of Immunology. 182:55-62
In conditions of optimal priming, the neonate possess competency to mount quantitatively adult-like responses. Vaccine formulations containing sufficiently potent adjuvants may overcome the neonates’ natural tendency for immunosuppression and provo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cb44845d4b0420f15938f31d47de87
https://doi.org/10.4049/jimmunol.182.1.55
https://doi.org/10.4049/jimmunol.182.1.55
Publikováno v:
International Immunology. 19:703-712
The functional capability of human neonatal CD4 T cells to respond to vaccine antigens is frequently described as Th2 biased, but whether this is due to defective T-cell or antigen-presenting cell (APC) function is unclear. In this study, we used pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27494e273ab56a6648b80552c5f6b6ef
https://doi.org/10.1093/intimm/dxm025
https://doi.org/10.1093/intimm/dxm025
Publikováno v:
Pediatric Surgery International. 22:24-30
The anti-inflammatory/immunoparalytic phase of the systemic inflammatory response syndrome (SIRS) following major insult (surgery, thermal/traumatic injury) is of major clinical importance in the neonate, during which the risk of infection is particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459080098415178ff7d8c75005210c61
https://doi.org/10.1007/s00383-005-1574-7
https://doi.org/10.1007/s00383-005-1574-7
Publikováno v:
Pediatric Surgery International. 21:335-340
The n-3 and n-6 polyunsaturated fatty acids (PUFAs) are essential dietary constituents. They are important as a source of energy, as structural components of cell membranes, and as signalling molecules. They have been demonstrated to be potent modula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c951e2397877b693c6d6ffca2fc44f
https://doi.org/10.1007/s00383-005-1385-x
https://doi.org/10.1007/s00383-005-1385-x
Publikováno v:
Scopus-Elsevier
Context.—The pathogenesis of appendicitis remains poorly understood. Despite new diagnostic techniques, appendices removed from patients with suspected appendicitis often appear histologically normal on conventional examination. There is increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb08d569793ffd3b68a05901a8110c4e
https://doi.org/10.5858/2003-127-0573-nhiaai
https://doi.org/10.5858/2003-127-0573-nhiaai
Autor:
Eleanor Rainsford, Denis J. Reen
Publikováno v:
British Journal of Haematology. 116:702-709
The use of human umbilical cord blood as an alternative source of stem cells to bone marrow for the reconstitution of the immune system is associated with less frequent and less severe incidence of graft-versus-host disease (GVHD). This study focuses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e34486b3337a099aa73bb3c7fd62827c
https://doi.org/10.1046/j.0007-1048.2001.03321.x
https://doi.org/10.1046/j.0007-1048.2001.03321.x
Autor:
Jaythoon Hassan, Denis J. Reen
Publikováno v:
The Journal of Immunology. 167:1970-1976
This study shows that, in humans at birth, circulating T cells represent recent thymic emigrants (RTEs) as reflected in their high level of expression of TCR excision circles. RTEs express “thymocyte-like” characteristics with regard to rapid rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc56c8f8a6118706288ca61b5730363
https://doi.org/10.4049/jimmunol.167.4.1970
https://doi.org/10.4049/jimmunol.167.4.1970
Publikováno v:
Immunology Today. 21:35-41
Recent experiments have led to renewed interest in differences between immune responses in adults and neonates. Here, Stuart Marshall-Clarke and colleagues discuss and propose a model suggesting that differences at the B-cell level might play an impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d182dc67ff05902c0307c7dfce5456
https://doi.org/10.1016/s0167-5699(99)01548-0
https://doi.org/10.1016/s0167-5699(99)01548-0
Autor:
Denis J. Reen, Jaythoon Hassan
Publikováno v:
European Journal of Immunology. 28:3057-3065
This study examines the influence of IL-7 on post-thymic CD4+ T cells using cord blood as a model system. Survival of naive cord blood T cells in the presence of IL-7 alone was significantly prolonged by up-regulating bcl-2, thereby preventing apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2df93a2ccb7b8b8b5883211f95658576
https://doi.org/10.1002/(sici)1521-4141(199810)28:10<3057::aid-immu3057>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199810)28:10<3057::aid-immu3057>3.0.co
Autor:
Denis J. Reen
Publikováno v:
Vaccine. 16:1401-1408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06561277ef9092b6737e0c66259de78e
https://doi.org/10.1016/s0264-410x(98)00099-1
https://doi.org/10.1016/s0264-410x(98)00099-1