Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Denis Headon"'
Autor:
Christos Dadousis, Adriana Somavilla, Joanna J. Ilska, Martin Johnsson, Lorena Batista, Richard J. Mellanby, Denis Headon, Paolo Gottardo, Andrew Whalen, David Wilson, Ian C. Dunn, Gregor Gorjanc, Andreas Kranis, John M. Hickey
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-14 (2021)
Abstract Background Body weight (BW) is an economically important trait in the broiler (meat-type chickens) industry. Under the assumption of polygenicity, a “large” number of genes with “small” effects is expected to control BW. To detect su
Externí odkaz:
https://doaj.org/article/af5cc1d8be434c6fb74eecfdab9242b5
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 4 (2019)
Patients with mutations in the ectodysplasin receptor signalling pathway genes – the X-linked ligand ectodysplasin-A (EDA), the receptor EDAR or the receptor adapter EDARADD – have hypohidrotic ectodermal dysplasia (HED). In addition to having im
Externí odkaz:
https://doaj.org/article/ced1855e543343a8bacfa69e06142629
Autor:
Kaustubh Adhikari, Macarena Fuentes-Guajardo, Mirsha Quinto-Sánchez, Javier Mendoza-Revilla, Juan Camilo Chacón-Duque, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Rodrigo Barquera Lozano, Gastón Macín Pérez, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Tábita Hunemeier, Virginia Ramallo, Caio C. Silva de Cerqueira, Malena Hurtado, Valeria Villegas, Vanessa Granja, Carla Gallo, Giovanni Poletti, Lavinia Schuler-Faccini, Francisco M. Salzano, Maria- Cátira Bortolini, Samuel Canizales-Quinteros, Michael Cheeseman, Javier Rosique, Gabriel Bedoya, Francisco Rothhammer, Denis Headon, Rolando González-José, David Balding, Andrés Ruiz-Linares
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Humans show great diversity in facial appearance and this variation is highly heritable. Here, Andres Ruiz-Linares and colleagues examined facial features in admixed Latin Americans and identify genome-wide associations for 14 facial traits, includin
Externí odkaz:
https://doaj.org/article/d07cc19f3fa148309d99800133b88ddc
Autor:
Kaustubh Adhikari, Tania Fontanil, Santiago Cal, Javier Mendoza-Revilla, Macarena Fuentes-Guajardo, Juan-Camilo Chacón-Duque, Farah Al-Saadi, Jeanette A. Johansson, Mirsha Quinto-Sanchez, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Rodrigo Barquera Lozano, Gastón Macín Pérez, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Tábita Hunemeier, Virginia Ramallo, Caio C. Silva de Cerqueira, Malena Hurtado, Valeria Villegas, Vanessa Granja, Carla Gallo, Giovanni Poletti, Lavinia Schuler-Faccini, Francisco M. Salzano, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Francisco Rothhammer, Gabriel Bedoya, Rolando Gonzalez-José, Denis Headon, Carlos López-Otín, Desmond J. Tobin, David Balding, Andrés Ruiz-Linares
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
By examining Latin American individuals of mixed European, Native American and African ancestry, Adhikari et al. identify novel loci influencing various features of facial and scalp hair. The study also provides experimental evidence that one of the
Externí odkaz:
https://doaj.org/article/0f97fbb66079458f805844b2d61b335e
Autor:
Denis Headon
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1004979 (2015)
Externí odkaz:
https://doaj.org/article/5e392fc4978a4c04ba728bca82b5dcfc
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112840 (2014)
Radiotherapy of head and neck cancers often results in collateral damage to adjacent salivary glands associated with clinically significant hyposalivation and xerostomia. Due to the reduced capacity of salivary glands to regenerate, hyposalivation is
Externí odkaz:
https://doaj.org/article/3f43370647974be0a4a6a283aacf9f85
Autor:
Cyril Charles, Sophie Pantalacci, Paul Tafforeau, Denis Headon, Vincent Laudet, Laurent Viriot
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e4985 (2009)
BACKGROUND: The Eda-A1-Edar signaling pathway is involved in the development of organs with an ectodermal origin, including teeth. In mouse, mutants are known for both the ligand, Eda-A1 (Tabby), and the receptor, Edar (Downless). The adult dentition
Externí odkaz:
https://doaj.org/article/5fbd3bf0027d4366ad90f095a7c81bf8
Autor:
Rakan Naboulsi, Jakub Cieślak, Denis Headon, Ahmad Jouni, Juan J. Negro, Göran Andersson, Gabriella Lindgren
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 561
Naboulsi, R, Cieślak, J, Headon, D, Jouni, A, Negro, J J, Andersson, G & Lindgren, G 2022, ' The Enrichment of Specific Hair Follicle-Associated Cell Populations in Plucked Hairs Offers an Opportunity to Study Gene Expression Underlying Hair Traits ', International Journal of Molecular Sciences, vol. 24, no. 1, pp. 1-13 . https://doi.org/10.3390/ijms24010561
Naboulsi, R, Cieślak, J, Headon, D, Jouni, A, Negro, J J, Andersson, G & Lindgren, G 2022, ' The Enrichment of Specific Hair Follicle-Associated Cell Populations in Plucked Hairs Offers an Opportunity to Study Gene Expression Underlying Hair Traits ', International Journal of Molecular Sciences, vol. 24, no. 1, pp. 1-13 . https://doi.org/10.3390/ijms24010561
Gene expression differences can assist in characterizing important underlying genetic mechanisms between different phenotypic traits. However, when population-dense tissues are studied, the signals from scarce populations are diluted. Therefore, appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276d486d15297ee0e34d03d1371f5011
https://pub.epsilon.slu.se/30398/
https://pub.epsilon.slu.se/30398/
Publikováno v:
Human Molecular Genetics
Hypohidrotic ectodermal dysplasia (HED) results from mutation of the EDA, EDAR or EDARADD genes and is characterized by reduced or absent eccrine sweat glands, hair follicles and teeth, and defective formation of salivary, mammary and craniofacial gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3075d0f9f6dff5cc6404de84adf842c7
https://pubmed.ncbi.nlm.nih.gov/27378689
https://pubmed.ncbi.nlm.nih.gov/27378689