Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Denis Gerlier"'
Autor:
François Enchéry, Claire Dumont, Mathieu Iampietro, Rodolphe Pelissier, Noémie Aurine, Louis-Marie Bloyet, Caroline Carbonnelle, Cyrille Mathieu, Chloé Journo, Denis Gerlier, Branka Horvat
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
In a study using both human cells and the African green monkeys, Enchery et al report that the highly pathogenic bat-borne Nipah virus (NiV), inhibits the NF-κB pathway via its nonstructural W protein. They demonstrate that it exerts this effect by
Externí odkaz:
https://doaj.org/article/dc79959663c145a4baf6f7ace28e5108
Autor:
Yasaman Karami, Paul Saighi, Rémy Vanderhaegen, Denis Gerlier, Sonia Longhi, Elodie Laine, Alessandra Carbone
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S19, Pp 1-20 (2020)
Abstract Background Coiled-coils are described as stable structural motifs, where two or more helices wind around each other. However, coiled-coils are associated with local mobility and intrinsic disorder. Intrinsically disordered regions in protein
Externí odkaz:
https://doaj.org/article/c4b97fa0ca044aaea8f46b21eb323d2d
Autor:
Marion Ferren, Alexandre Lalande, Mathieu Iampietro, Lola Canus, Didier Decimo, Denis Gerlier, Matteo Porotto, Cyrille Mathieu
Publikováno v:
Viruses, Vol 15, Iss 1, p 229 (2023)
The cessation of measles virus (MeV) vaccination in more than 40 countries as a consequence of the COVID-19 pandemic is expected to significantly increase deaths due to measles. MeV can infect the central nervous system (CNS) and lead to lethal encep
Externí odkaz:
https://doaj.org/article/8939481177544170be2696de969195ea
Publikováno v:
Viruses, Vol 14, Iss 12, p 2641 (2022)
The immune system deploys a complex network of cells and signaling pathways to protect host integrity against exogenous threats, including measles virus (MeV). However, throughout its evolutionary path, MeV developed various mechanisms to disrupt and
Externí odkaz:
https://doaj.org/article/6dd71b4342894ecc82c9b1bb0f6d178d
Autor:
Mathieu Iampietro, Claire Dumont, Cyrille Mathieu, Julia Spanier, Jonathan Robert, Aude Charpenay, Sébastien Dupichaud, Kévin P. Dhondt, Noémie Aurine, Rodolphe Pelissier, Marion Ferren, Stéphane Mély, Denis Gerlier, Ulrich Kalinke, Branka Horvat
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102519- (2021)
Summary: During inflammatory diseases, cancer, and infection, the cGAS/STING pathway is known to recognize foreign or self-DNA in the cytosol and activate an innate immune response. Here, we report that negative-strand RNA paramyxoviruses, Nipah viru
Externí odkaz:
https://doaj.org/article/96c2bebe7698404c86554982f7f643c3
Autor:
Edoardo Salladini, Frank Gondelaud, Juliet F. Nilsson, Giulia Pesce, Christophe Bignon, Maria Grazia Murrali, Roxane Fabre, Roberta Pierattelli, Andrey V. Kajava, Branka Horvat, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1324 (2021)
Henipaviruses are BSL-4 zoonotic pathogens responsible in humans for severe encephalitis. Their V protein is a key player in the evasion of the host innate immune response. We previously showed that the Henipavirus V proteins consist of a long intrin
Externí odkaz:
https://doaj.org/article/234e3d406813456f85406aebe2351b06
Autor:
Jeremy Welsch, Claire Lionnet, Christophe Terzian, Branka Horvat, Denis Gerlier, Cyrille Mathieu
Publikováno v:
Bio-Protocol, Vol 7, Iss 22 (2017)
According to the World Health Organization (WHO), at least 50% of emerging viruses endowed with pathogenicity in humans can infect the Central Nervous System (CNS) with induction of encephalitis and other neurologic diseases (Taylor et al., 2001; Oli
Externí odkaz:
https://doaj.org/article/9ddde7c7175243ba88f9133aaf3a420e
Autor:
Kevin Tartour, Xuan-Nhi Nguyen, Romain Appourchaux, Sonia Assil, Véronique Barateau, Louis-Marie Bloyet, Julien Burlaud Gaillard, Marie-Pierre Confort, Beatriz Escudero-Perez, Henri Gruffat, Saw See Hong, Marie Moroso, Olivier Reynard, Stéphanie Reynard, Elodie Decembre, Najate Ftaich, Axel Rossi, Nannan Wu, Frédérick Arnaud, Sylvain Baize, Marlène Dreux, Denis Gerlier, Glaucia Paranhos-Baccala, Viktor Volchkov, Philippe Roingeard, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006610 (2017)
IFITMs are broad antiviral factors that block incoming virions in endosomal vesicles, protecting target cells from infection. In the case of HIV-1, we and others reported the existence of an additional antiviral mechanism through which IFITMs lead to
Externí odkaz:
https://doaj.org/article/a1ae7ec7be9d4b84a06a17adedcfc46d
Autor:
Audrey Jean, Florence Tardy, Omran Allatif, Isabelle Grosjean, Bariza Blanquier, Denis Gerlier
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172358 (2017)
Mycoplasmas (a generic name for Mollicutes) are a predominant bacterial contaminant of cell culture and cell derived products including viruses. This prokaryote class is characterized by very small size and lack of a cell wall. Consequently, mycoplas
Externí odkaz:
https://doaj.org/article/bb4516e1cd34488aba838cb49c1d2adc
Autor:
Louis-Marie Bloyet, Joanna Brunel, Marion Dosnon, Véronique Hamon, Jenny Erales, Antoine Gruet, Carine Lazert, Christophe Bignon, Philippe Roche, Sonia Longhi, Denis Gerlier
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006058 (2016)
Measles virus (MeV) and all Paramyxoviridae members rely on a complex polymerase machinery to ensure viral transcription and replication. Their polymerase associates the phosphoprotein (P) and the L protein that is endowed with all necessary enzymati
Externí odkaz:
https://doaj.org/article/a1aabcaba6c34ec1b458849c2a92a534