Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Denis Gaucher"'
Autor:
Brad R Rosenberg, Marion Depla, Catherine A Freije, Denis Gaucher, Sabrina Mazouz, Maude Boisvert, Nathalie Bédard, Julie Bruneau, Charles M Rice, Naglaa H Shoukry
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007290 (2018)
Most individuals exposed to hepatitis C virus (HCV) become persistently infected while a minority spontaneously eliminate the virus. Although early immune events influence infection outcome, the cellular composition, molecular effectors, and timefram
Externí odkaz:
https://doaj.org/article/b465ecfd4e654bf39641f37a32ae4bfe
Publikováno v:
Immunology Letters. 161:65-75
CD86 and CD80, the ligands for the co-stimulatory molecules CD28 and CTLA-4, are members of the Ig superfamily. Their structure includes Ig variable-like (IgV) domains, Ig constant-like (IgC) domains and intracellular domains. Although crystallograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d2a266682e691844babf4bced31cb6
https://doi.org/10.1016/j.imlet.2014.05.002
https://doi.org/10.1016/j.imlet.2014.05.002
Autor:
Farzaneh Jalili, Dominique Gauchat, Martin Duddy, Tarik Touil, Joumana Zeidan, Jacqueline T. Chen, Harold L. Atkins, Denis Gaucher, Douglas L. Arnold, Rémi Cheynier, Rachel Corsini, Rafick Pierre Sekaly, Jack P. Antel, Nathalie Arbour, Peter J. Darlington, Amit Bar-Or, Ho Jin Kim, Hania Kebir, Mark S. Freedman, Alexandre Prat, Marjorie A. Bowman, Jean Sebastien Doucet
Publikováno v:
Annals of Neurology. 73:341-354
Objective To define changes in phenotype and functional responses of reconstituting T cells in patients with aggressive multiple sclerosis (MS) treated with ablative chemotherapy and autologous hematopoietic stem cell transplantation (HSCT). Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9e69f09facd57a22ef953d75f643a4
https://doi.org/10.1002/ana.23784
https://doi.org/10.1002/ana.23784
Autor:
Catherine A. Freije, Nathalie Bédard, Naglaa H. Shoukry, Maude Boisvert, Charles M. Rice, Marion Depla, Brad R. Rosenberg, Denis Gaucher, Sabrina Mazouz, Julie Bruneau
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007290 (2018)
PLoS Pathogens
PLoS Pathogens
Most individuals exposed to hepatitis C virus (HCV) become persistently infected while a minority spontaneously eliminate the virus. Although early immune events influence infection outcome, the cellular composition, molecular effectors, and timefram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d440f91e90708a9a52c1fed25ad26f3e
https://doi.org/10.1371/journal.ppat.1007290
https://doi.org/10.1371/journal.ppat.1007290
Autor:
Janice M. Moser, Rama Akondy, Elias A. Said, Bader Yassine-Diab, Rafick Pierre Sekaly, Aline Rinfret, Peter Wilkinson, Mark J. Cameron, Robert S. Balderas, Denis Gaucher, Nadia Kettaf, David J. Kelvin, Jim Tartaglia, Geneviève Boucher, Robert Clum, Elias K. Haddad, Bastian R. Angermann, Abdelali Filali-Mouhim, Giuseppe Pantaleo, René Therrien, Riyaz Mehta, Donald Drake, Roland Somogyi, Erika Castro, Larry D. Greller, Younes Chouikh
Publikováno v:
Journal of Experimental Medicine, vol. 205, no. 13, pp. 3119-3131
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Correlates of immune-mediated protection to most viral and cancer vaccines are still unknown. This impedes the development of novel vaccines to incurable diseases such as HIV and cancer. In this study, we have used functional genomics and polychromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dbe2aaa023407cc208320d2ccd99cc
https://doi.org/10.1084/jem.20082292
https://doi.org/10.1084/jem.20082292
Autor:
Denis Gaucher, Kris Chadee
Publikováno v:
Parasite Immunology. 25:55-58
SUMMARY Entamoeba histolytica is the aetiological agent of invasive amoebiasis, the third leading parasitic cause of mortality in the world. The disease can be easily cured by chemotherapy; however, prevention, mainly in the form of vaccination, coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d025e6aa0e25379b46dce4b2a61b2c7e
https://doi.org/10.1046/j.1365-3024.2003.00607.x
https://doi.org/10.1046/j.1365-3024.2003.00607.x
Autor:
Sharon Isern, Rafael Cubas, Josephine Birungi, Lydie Trautmann, Josephine H. Cox, C. Schmidt, Jill Gillmour, Divya Srinivasan, Pearline Ngauv, Enoch Muyanja, Elias K. Haddad, Rafick Pierre Sekaly, Guido Silvestri, Jakub Kopycinski, Erika Castro, Benton Lawson, Pontiano Kaleebu, Giuseppe Pantaleo, Dawne K. Rowe, Scott F. Michael, Glenda Canderan, Noah Kiwanuka, Thomas H. Vanderford, Aloysius Ssemaganda, Michaela J. Smith, Joel Singer, Amanda S. Graham, Helene Perrin, Patricia E. Fast, Denis Gaucher, Annet Nanvubya
Background. Defining the parameters that modulate vaccine responses in African populations will be imperative to design effective vaccines for protection against HIV, malaria, tuberculosis, and dengue virus infections. This study aimed to evaluate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b898b566fb4e841c6f000df16bae2f
https://europepmc.org/articles/PMC4071376/
https://europepmc.org/articles/PMC4071376/
Autor:
Denis Gaucher, Kris Chadee
Publikováno v:
Cytokine. 14:177-183
Complementary DNAs coding for gerbil interleukin 12 (IL-12) p40/p35 subunits were cloned by a combination of cross species reverse transcriptase-polymerase chain reaction (RT-PCR) and 3' rapid amplification of cDNA ends (RACE) techniques. IL-12 p40/p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1515cfc428d76d8fab7d6b69f0948ef8
https://doi.org/10.1006/cyto.2001.0866
https://doi.org/10.1006/cyto.2001.0866
Publikováno v:
Clinical Immunology and Immunopathology. 81:74-81
Control of infections by the obligate intramacrophage protozoan parasiteLeishmania donovaniis traditionally done with pentavalent antimonial drugs. It was of interest to determine if immunotherapy with IL-2-stimulated splenocytes would enhance drug a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6566613f7771b21da64b292857c8bd14
https://doi.org/10.1006/clin.1996.0160
https://doi.org/10.1006/clin.1996.0160
Autor:
Denis Gaucher, Rafick-Pierre Sekaly, Geneviève Beaulé, Oreste Acuto, Frédérique Michel, Tanya Girard, Walid Mourad, Mohamed El-Far
Publikováno v:
Biochemical and biophysical research communications. 423(2)
T cell activation requires both antigen specific and co-stimulatory signals that include the interaction of CD28 with its ligands CD80 and CD86. These signals are delivered by antigen presenting cells (APC) in the context of the immunological synapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2a6c926d5e51bb953a03cbf65b69f0
http://ora.ox.ac.uk/objects/uuid:591a1058-303e-41ff-b5e0-2bd3167d1769
http://ora.ox.ac.uk/objects/uuid:591a1058-303e-41ff-b5e0-2bd3167d1769