Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Denis Gallagher"'
Autor:
Fyyaz Siddiqui, Denis Gallagher, Hannah Shuster-Hyman, Lianet Lopez, Andrée Gauthier-Fisher, Clifford L Librach
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background The Kynurenine Pathway (KP) of tryptophan degradation and glutamate toxicity is implicated in several neurological disorders, including depression. The therapeutic potential of mesenchymal stromal cells (MSC), owing to their well
Externí odkaz:
https://doaj.org/article/032d05b5794145f59802b995ec826733
Autor:
Lianet Lopez, Hannah Shuster-Hyman, Eden Marco, Hasna Khan, Avishai Gasner, Aleksandra Uzelac, Brandon Wyse, Poonam Mander, Mugundhine Sangaralingam, Joseph Fish, Ariel Gorodensky, Samar Mouazz, Amanda Kauffman, Denis Gallagher, Andrée Gauthier-Fisher, Clifford L. Librach
Publikováno v:
Stem Cells International, Vol 2023 (2023)
First trimester (FTM) and term human umbilical cord perivascular cells are promising mesenchymal stromal cell candidates to mitigate side effects of oncotherapy, but their safety for cancer patients remains to be determined. This study was designed t
Externí odkaz:
https://doaj.org/article/d8e68fc7c05546b9a0c452adbb4a4a7b
Autor:
Hannah, Shuster-Hyman, Fyyaz, Siddiqui, Denis, Gallagher, Andrée, Gauthier-Fisher, Clifford L, Librach
Publikováno v:
Cytotherapy. 25:125-137
Because of their potent immunomodulatory and anti-inflammatory properties, mesenchymal stromal cells are a major focus in the field of stem cell therapy. However, the precise mechanisms underlying this are not entirely understood. Human umbilical cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7dd428ddd12e2216ba3492b78aa92d
https://doi.org/10.1016/j.jcyt.2022.10.014
https://doi.org/10.1016/j.jcyt.2022.10.014
Autor:
Mekayla A. Storer, Denis Gallagher, Michael P. Fatt, Jaclin V. Simonetta, David R. Kaplan, Freda D. Miller
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1464-1480 (2018)
Summary: Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the identity of these circulating cues is still being defined. Here, we have focused on the cytokine interleukin-6 (IL-6), since increased circulating levels
Externí odkaz:
https://doaj.org/article/413de4bec0704eb2b2049d3c965c3187
Autor:
Guang Yang, Gonzalo I. Cancino, Siraj K. Zahr, Axel Guskjolen, Anastassia Voronova, Denis Gallagher, Paul W. Frankland, David R. Kaplan, Freda D. Miller
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1022-1036 (2016)
Maternal diabetes is known to adversely influence brain development in offspring. Here, we provide evidence that this involves the circulating metabolite methylglyoxal, which is increased in diabetes, and its detoxifying enzyme, glyoxalase 1 (Glo1),
Externí odkaz:
https://doaj.org/article/7a23eaa5baf6414cb5912d376c6df4dc
Autor:
Tanya Barretto, Katya Park, Denis Gallagher, Shlomit Kenigsberg, Elaine Liu, Eugene Park, Leila Maghen, Andrew J Baker, Clifford Librach, Andrée Gauthier-Fisher
Publikováno v:
Stem Cells and Development. 29:198-211
Traumatic brain injury (TBI) leads to delayed secondary injury events consisting of cellular and molecular cascades that exacerbate the initial injury. Human umbilical cord perivascular cells (HUCPVCs) secrete neurotrophic and prosurvival factors. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d34d782cf42ed7d63e45a6a35a41c3
https://doi.org/10.1089/scd.2019.0135
https://doi.org/10.1089/scd.2019.0135
Autor:
Maxwell Charlat, Andrée Gauthier-Fisher, Fyyaz Siddiqui, Joseph Fish, Clifford Librach, Siddiq Moolla, Emaan Chaudry, Denis Gallagher
Publikováno v:
Biological Psychiatry. 86:712-724
Background Hyperactivation of innate immunity has been implicated in the etiology of mood disorders, including major depressive disorder (MDD). Mesenchymal stromal cells (MSCs) have demonstrated potent immunomodulatory capabilities in the context of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea23965fec50eaf4412cb658856a359
https://doi.org/10.1016/j.biopsych.2019.07.015
https://doi.org/10.1016/j.biopsych.2019.07.015
Autor:
Tamar Telliyan, Elaine Liu, Eugene Park, Denis Gallagher, Clifford Librach, Tanya Barretto, Andrew J. Baker
Publikováno v:
Journal of neurotrauma. 38(19)
Vascular dysfunction arising from blood-brain barrier (BBB) breakdown after traumatic brain injury (TBI) can adversely affect neuronal health and behavioral outcome. Pericytes and endothelial cells of the neurovascular unit (NVU) function collectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168c0b4edb71d90e36156580e823347e
https://pubmed.ncbi.nlm.nih.gov/33899499
https://pubmed.ncbi.nlm.nih.gov/33899499
Autor:
Michael P. Fatt, Mekayla Storer, David L. Kaplan, Freda D. Miller, Jaclin V. Simonetta, Denis Gallagher
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1464-1480 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the identity of these circulating cues is still being defined. Here, we have focused on the cytokine interleukin-6 (IL-6), since increased circulating levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb67680fe04829acd576ceda6d29ba2
http://www.sciencedirect.com/science/article/pii/S2213671118301358
http://www.sciencedirect.com/science/article/pii/S2213671118301358
Autor:
Denis Gallagher
The author is a Scot from the small (two shop) village of Whins of Milton, two miles south of the Royal Burgh of Stirling. He has always loved the sea and ships, and was master of the first Australian flag anchor handler, operating in offshore oilfie
