Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Denis G Knyazev"'
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193454 (2018)
Proton transport at water/membrane interfaces plays a fundamental role for a myriad of bioenergetic processes. Here we have performed ab initio molecular dynamics simulations of proton transfer along two phosphatidylcholine bilayers. As found in prev
Externí odkaz:
https://doaj.org/article/92a40f7d291c4e749f093813de1f1ada
Autor:
Denis G. Knyazev, Lukas Winter, Andreas Vogt, Sandra Posch, Yavuz Öztürk, Christine Siligan, Nikolaus Goessweiner-Mohr, Nora Hagleitner-Ertugrul, Hans-Georg Koch, Peter Pohl
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1774 (2023)
The universally conserved protein YidC aids in the insertion and folding of transmembrane polypeptides. Supposedly, a charged arginine faces its hydrophobic lipid core, facilitating polypeptide sliding along YidC’s surface. How the membrane barrier
Externí odkaz:
https://doaj.org/article/4a5b2448fb7b4c3581e73361d01c6d93
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1641 (2023)
The high propensity of protons to stay at interfaces has attracted much attention over the decades. It enables long-range interfacial proton diffusion without relying on titratable residues or electrostatic attraction. As a result, various phenomena
Externí odkaz:
https://doaj.org/article/e632d89426e249259b2b7bc5f63984b3
Autor:
Anna S. Loshkareva, Marina M. Popova, Liudmila A. Shilova, Natalia V. Fedorova, Tatiana A. Timofeeva, Timur R. Galimzyanov, Petr I. Kuzmin, Denis G. Knyazev, Oleg V. Batishchev
Publikováno v:
Membranes, Vol 13, Iss 1, p 76 (2023)
Topological rearrangements of biological membranes, such as fusion and fission, often require a sophisticated interplay between different proteins and cellular membranes. However, in the case of fusion proteins of enveloped viruses, even one molecule
Externí odkaz:
https://doaj.org/article/990a50ff123246bb83864804063c70f6
Autor:
Ewald Weichselbaum, Maria Österbauer, Denis G. Knyazev, Oleg V. Batishchev, Sergey A. Akimov, Trung Hai Nguyen, Chao Zhang, Günther Knör, Noam Agmon, Paolo Carloni, Peter Pohl
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Proton diffusion along biological membranes is vitally important for cellular energetics. Here we extended previous time-resolved fluorescence measurements to study the time and temperature dependence of surface proton transport. We determin
Externí odkaz:
https://doaj.org/article/e79296c0e9db4ab09bce85c16733cc1a
Autor:
Ilie Sachelaru, Lukas Winter, Denis G. Knyazev, Mirjam Zimmermann, Andreas Vogt, Roland Kuttner, Nicole Ollinger, Christine Siligan, Peter Pohl, Hans-Georg Koch
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent c
Externí odkaz:
https://doaj.org/article/4a079782df9745798e53ae586a20f9e7
Autor:
Denis G. Knyazev, Mirjam Schaur, Roland Kuttner, Christine Siligan, Nikolaus Gössweiner-Mohr, Nora Hagleitner-Ertugrul, Peter Pohl
In concert with irreversible non-equilibrium peptide translation by the ribosome, the nascent polypeptide chain may integrate into the membrane or translocate to the other side of the membrane, facilitated by the conserved protein translocation chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db3710c140abb865ef4fe598e1a9090d
https://doi.org/10.1101/2023.01.10.523415
https://doi.org/10.1101/2023.01.10.523415
Autor:
Denis G. Knyazev, Roland Kuttner, Ana-Nicoleta Bondar, Mirjam Zimmerman, Christine Siligan, Peter Pohl
Publikováno v:
Biomolecules, Vol 10, Iss 1, p 78 (2020)
The bacterial channel SecYEG efficiently translocates both hydrophobic and hydrophilic proteins across the plasma membrane. Translocating polypeptide chains may dislodge the plug, a half helix that blocks the permeation of small molecules, from its p
Externí odkaz:
https://doaj.org/article/c508f658f103454396df2a6b80f09f53
Autor:
Johann Wachlmayr, Laxmicharan Samineni, Denis G. Knyazev, Thomas Barta, Armin Speletz, Chenhao Yao, Hyeonji Oh, Harekrushna Behera, Tingwei Ren, Manish Kumar, Andreas Horner
Publikováno v:
Journal of Membrane Science. 675:121308
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d35ac1ef99f468a612eae1a1c34791c
https://doi.org/10.1016/j.memsci.2022.121308
https://doi.org/10.1016/j.memsci.2022.121308
Autor:
Nikolaus Gössweiner-Mohr, Stefanie Lenzeder, Ferdinand Horvath, Denis G. Knyazev, Thomas Renger, Peter Pohl
Publikováno v:
Biophysical Journal. 122:525a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46b29a59338afb4004f8dff7e07aaad2
https://doi.org/10.1016/j.bpj.2022.11.2791
https://doi.org/10.1016/j.bpj.2022.11.2791