Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Denis Drapeau"'
Publikováno v:
Handbook of Validation in Pharmaceutical Processes ISBN: 9781003163138
Handbook of Validation in Pharmaceutical Processes
Handbook of Validation in Pharmaceutical Processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327c368a36727d7f7dfb51c095f7eed5
https://doi.org/10.1201/9781003163138-37
https://doi.org/10.1201/9781003163138-37
Autor:
Denis Drapeau
Publikováno v:
Neurobiology of Learning and Memory. 155:486-497
In animal behavioral experiments, extended training causes instrumental actions that deliver ingestible substances to lose sensitivity to outcome devaluation and contingency degradation, and to gain direct sensitivity to the current motivational stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464f7e5e5880f38201280471c8584e66
https://doi.org/10.1016/j.nlm.2018.09.011
https://doi.org/10.1016/j.nlm.2018.09.011
Publikováno v:
Eng Life Sci
The application of PAT for in-line monitoring of biopharmaceutical manufacturing operations has a central role in developing more robust and consistent processes. Various spectroscopic techniques have been applied for collecting real-time data from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fad6598b00ca0a347bf096a73c3418c
https://doi.org/10.1002/elsc.201700084
https://doi.org/10.1002/elsc.201700084
Autor:
Yen-Tung Luan, Denis Drapeau, Jordy DeFelice, Amy Kittredge, Matthew Gagnon, Gregory Walter Hiller
Publikováno v:
Biotechnology and bioengineering. 108(6)
A simple method for control of lactate accumulation in suspension cultures of Chinese hamster ovary (CHO) cells based on the culture's pH was developed. When glucose levels in culture reach a low level (generally below 1 mM) cells begin to take up la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618d45fe534d5d483e14fa185a92ae1c
https://pubmed.ncbi.nlm.nih.gov/21328318
https://pubmed.ncbi.nlm.nih.gov/21328318
Autor:
Kathy Hsiao, Jen-i Mao, Denis Drapeau, Jeff S. Socolow, George C. Avgerinos, Robert J. Broeze
Publikováno v:
Nature Biotechnology. 8:54-58
We have used a 20 liter stirred tank fermentor, equipped with a 127 mesh ethylene-tetrafluoroethylene rotating screen for cell recycle, for the continuous production of recombinant single chain urokinase-type plasminogen activator (rscu-PA) from Chin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d91f8ed29f2c68ea326791159b1d42
https://doi.org/10.1038/nbt0190-54
https://doi.org/10.1038/nbt0190-54
Autor:
S. Robert Adamson, Mark Leonard, Timothy S. Charlebois, Martin S. Sinacore, Scott Harrison, Denis Drapeau
Publikováno v:
Encyclopedia of Industrial Biotechnology ISBN: 9780471799306
Encyclopedia of Industrial Biotechnology
Encyclopedia of Industrial Biotechnology
Factors that Affect Genetic Stability of Endogenous Genes Oncogenic Transformation, Aneuploidy, and Genetic Stability Molecular Regulation of Genetic Stablity Genotypic and Phenotypic Stability of Recombinant Cell Lines Stable Integration of Heterolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505cfe19af48f7db7067a8b38800b4c6
https://doi.org/10.1002/0471250570.spi044
https://doi.org/10.1002/0471250570.spi044
Autor:
Denis Drapeau, Elisabeth Lindner-Ollsson, Helena Sandberg, Anna-Lisa Smeds, Mats Olofsson, Veronique Chotteau, Nathalie Chatzissavidou, Helena Brink-Nilsson, Sarah Boork, Christel Fenge, Johan Rosenquist, Torsten Björling
Publikováno v:
Animal Cell Technology: From Target to Market ISBN: 9789401038973
A large scale biopharmaceutical process has been developed for the production of a genetically engineered variant of coagulation factor VIII. Factor VIII is the coagulation protein that is defective or missing in hemophilia A. Two challenging techniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb4b0ffd794dafe67839a0b39516880d
https://doi.org/10.1007/978-94-010-0369-8_67
https://doi.org/10.1007/978-94-010-0369-8_67
Publikováno v:
Molecular biotechnology. 15(3)
A three-step protocol is described for adapting an anchorage-dependent, serum-dependent recombinant mammalian cell lineage to high density serum-free suspension culture. The objective is a cell lineage that is well-suited for the manufacture of a rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2327b22babcc4c741ba35819bd3d23fe
https://pubmed.ncbi.nlm.nih.gov/10986701
https://pubmed.ncbi.nlm.nih.gov/10986701
Autor:
S. R. Adamson, D. C. Cohen, Martin S. Sinacore, Yen-Tung Luan, Denis Drapeau, D. T. Richards, J. A. Popoloski
Publikováno v:
Cytotechnology. 15(1-3)
In a batch-refeed continuous process involving a recombinant Chinese hamster ovary cell line, a brief upset was occasionally observed during which cell growth halted and cell viability dropped. This was found to be associated with depletion of insuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c00b2365b8fa779a115f284e78f83c
https://pubmed.ncbi.nlm.nih.gov/7765921
https://pubmed.ncbi.nlm.nih.gov/7765921