Zobrazeno 1 - 10
of 366
pro vyhledávání: '"Denis, Guilloteau"'
Autor:
Christine Vala, Céline Mothes, Gabrielle Chicheri, Pauline Magadur, Gilles Viot, Jean-Bernard Deloye, Serge Maia, Yann Bouvet, Anne-Claire Dupont, Nicolas Arlicot, Denis Guilloteau, Patrick Emond, Johnny Vercouillie
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-14 (2020)
Abstract Background Fluorine labelled 8-((E)-4-fluoro-but-2-enyl)-3β-p-tolyl-8-aza-bicyclo[3.2.1]octane-2β-carboxylic acid methyl ester ([18F]LBT999) is a selective radioligand for the in vivo neuroimaging and quantification of the dopamine transpo
Externí odkaz:
https://doaj.org/article/cc76bd2c9b0b41288b696111b1292997
Autor:
Jonathan Elie, Johnny Vercouillie, Nicolas Arlicot, Lucas Lemaire, Rudy Bidault, Sylvie Bodard, Christel Hosselet, Jean-Bernard Deloye, Sylvie Chalon, Patrick Emond, Denis Guilloteau, Frédéric Buron, Sylvain Routier
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1-7 (2019)
A series of novel derivatives exhibiting high affinity and selectivity towards the COX-2 enzyme in the (aza) indazole series was developed. A short synthetic route involving a bromination/arylation sequence under microwave irradiation and direct C–
Externí odkaz:
https://doaj.org/article/e9cfd14b1cb34e65971969a050ec7b00
Autor:
Maria-Joao Ribeiro, Johnny Vercouillie, Nicolas Arlicot, Clovis Tauber, Valérie Gissot, Karl Mondon, Laurent Barantin, Jean-Philippe Cottier, Serge Maia, Jean-Bernard Deloye, Patrick Emond, Denis Guilloteau
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Purpose: The density of the neuronal dopamine transporter (DAT) is directly correlated with the presynaptic dopaminergic system injury. In a first study, we evaluated the brain distribution and kinetics of [18F]LBT-999, a DAT PET radioligand, in a gr
Externí odkaz:
https://doaj.org/article/3b7e621efc8e41288c0d9972cc466b78
Autor:
Sylvie Chalon, Johnny Vercouillie, Pierre Payoux, Jean-Bernard Deloye, Cécile Malherbe, Florence Le Jeune, Nicolas Arlicot, Anne-Sophie Salabert, Denis Guilloteau, Patrick Emond, Maria-Joao Ribeiro
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
The membrane dopamine transporter (DAT) is involved in a number of brain disorders and its exploration by positron emission tomography (PET) imaging is highly relevant for the early and differential diagnosis, follow-up and treatment assessment of th
Externí odkaz:
https://doaj.org/article/fe0d6108515745319cb050faaa6231de
Autor:
Johnny, Vercouillie, Frédéric, Buron, Sophie, Sérrière, Nuno, Rodrigues, Zuhal, Gulhan, Agnès, Chartier, Gabrielle, Chicheri, Hamid, Marzag, Adeline, Oury, Nathalie, Percina, Sylvie, Bodard, Rajah, Ben Othman, Julie, Busson, Franck, Suzenet, Denis, Guilloteau, Mathieu, Marchivie, Patrick, Emond, Sylvain, Routier, Sylvie, Chalon
Publikováno v:
European journal of medicinal chemistry. 244
Age-related neurodegenerative diseases have in common the occurrence of cognitive impairment, a highly incapacitating process that involves the cholinergic neurotransmission system. The vesicular acetylcholine transporter (VAChT) positron emission to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e741084a39e3c6ac3e6cf5e4cc49aa7d
https://pubmed.ncbi.nlm.nih.gov/36252395
https://pubmed.ncbi.nlm.nih.gov/36252395
Autor:
Emilie Beaufils, Maria Joao Ribeiro, Emilie Vierron, Johnny Vercouillie, Diane Dufour-Rainfray, Jean-Philippe Cottier, Vincent Camus, Karl Mondon, Denis Guilloteau, Caroline Hommet
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 4, Iss 3, Pp 431-441 (2014)
Background: Posterior cortical atrophy (PCA) is characterized by progressive higher-order visuoperceptual dysfunction and praxis declines. This syndrome is related to a number of underlying diseases, including, in most cases, Alzheimer's disease (AD)
Externí odkaz:
https://doaj.org/article/1a6906e8c8644072aa35b328e4ca987d
Publikováno v:
Médecine Nucléaire. 45:127-134
Resume Les tumeurs neuroendocrines (TNE) sont un groupe heterogene de tumeurs qui proviennent de cellules neuroendocrines pouvant se developper sur divers organes. La plupart sont bien differenciees et ont la capacite de produire des amines biogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b3a19a7a807d269e4889859539e94b
https://doi.org/10.1016/j.mednuc.2021.03.005
https://doi.org/10.1016/j.mednuc.2021.03.005
Autor:
J.B. Deloye, Jean-Philippe Cottier, Malherbe C, Bidault R, Laurent Barantin, S. Maia, Denis Guilloteau, Johnny Vercouillie, Gissot, Nicolas Arlicot, M.J. Ribeiro
Publikováno v:
The Quarterly Journal of Nuclear Medicine and Molecular Imaging. 66
BACKGROUND To evaluate in healthy human brain the distribution, uptake, and kinetics of [18F]LBT-999, a PET ligand targeting the dopamine transporter, to assess its ability to explore dopaminergic innervation, using a shorter protocol, more convenien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a762fe411980783bee1f5d2a3d2bb5
https://doi.org/10.23736/s1824-4785.19.03175-3
https://doi.org/10.23736/s1824-4785.19.03175-3
Autor:
Clément Thomas MD, Johnny Vercouillie PhD, Aurélie Doméné, Clovis Tauber PhD, Michael Kassiou PhD, Denis Guilloteau PhD, Christophe Destrieux MD, PhD, Sophie Sérrière PhD, Sylvie Chalon PhD
Publikováno v:
Molecular Imaging, Vol 15 (2016)
Subarachnoid hemorrhage (SAH) can lead to delayed cerebral ischemia, which increases the rate of morbidity and mortality. The detection of microglial activation may serve as a biomarker for the identification of patients at risk of this deleterious c
Externí odkaz:
https://doaj.org/article/c96fbf9b602040dab1a0d15413dcb484
Autor:
Fabienne Gourand, Nahid Amini, Zhisheng Jia, Sharon Stone-Elander, Denis Guilloteau, Louisa Barré, Christer Halldin
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137160 (2015)
In quantitative PET measurements, the analysis of radiometabolites in plasma is essential for determining the exact arterial input function. Diphenyl sulfide compounds are promising PET and SPECT radioligands for in vivo quantification of the seroton
Externí odkaz:
https://doaj.org/article/2c6274ff38c74d8cad57cd0784512fbc