Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Denis, Burdakov"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Lateral hypothalamic (LH) hypocretin/orexin neurons (HONs) control brain-wide electrical excitation. Abnormally high excitation produces epileptic seizures, which affect millions of people and need better treatments. HON population activity
Externí odkaz:
https://doaj.org/article/199cc29e2be84e878ed018bd72d8768d
Publikováno v:
eLife, Vol 12 (2024)
Dopamine and orexins (hypocretins) play important roles in regulating reward-seeking behaviors. It is known that hypothalamic orexinergic neurons project to dopamine neurons in the ventral tegmental area (VTA), where they can stimulate dopaminergic n
Externí odkaz:
https://doaj.org/article/8283c27b38cb4045981fb9599b10407b
Autor:
Keshav S. Subramanian, Logan Tierno Lauer, Anna M. R. Hayes, Léa Décarie-Spain, Kara McBurnett, Anna C. Nourbash, Kristen N. Donohue, Alicia E. Kao, Alexander G. Bashaw, Denis Burdakov, Emily E. Noble, Lindsey A. Schier, Scott E. Kanoski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Food intake is determined by learned appetitive responses and physiological “appetition” signals after eating begins. Here, authors show melanin-concentrating hormone (MCH)-producing neurons integrate these processes to promote caloric intake.
Externí odkaz:
https://doaj.org/article/caedcaf785af4d0d94e9c35c64f6fd32
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104396- (2022)
Summary: During wakefulness, the VTA represents the valence of experiences and mediates affective response to the outside world. Recent work revealed that two major VTA populations – dopamine and GABA neurons – are highly active during REM sleep
Externí odkaz:
https://doaj.org/article/564b9f24c84646329ea31e4e18a7f847
Autor:
Christin Kosse, Denis Burdakov
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Hypothalamus is implicated in memory disorders but the neural mechanisms are unknown. Here, the authors report that MCH expressing hypothalamic neurons respond to novel object exposure, are inhibited by local GAD65 expressing neurons and these local
Externí odkaz:
https://doaj.org/article/9cb8c0058d13439080b6efe8a4730ed3
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Across sleep and wakefulness, brain function requires inter-neuronal interactions lasting beyond seconds. Yet, most studies of neural circuit connectivity focus on millisecond-scale interactions mediated by the classic fast transmitters, GABA and glu
Externí odkaz:
https://doaj.org/article/1fe7fc6c8f5d493089490d8c38c8f388
Autor:
Cristina Concetti, Denis Burdakov
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The lateral hypothalamus (LH) is classically implicated in sleep-wake control. It is the main source of orexin/hypocretin and melanin-concentrating hormone (MCH) neuropeptides in the brain, which have been both implicated in arousal state switching.
Externí odkaz:
https://doaj.org/article/5376bcba43cf4c9e824ae130603c1686
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
It is well known that alcohol consumption leads to overeating however the neural mechanisms are unclear. Here the authors demonstrate that hunger promoting Agrp neurons in hypothalamus are also activated by ethanol and are necessary for ethanol-induc
Externí odkaz:
https://doaj.org/article/0060c7d2281240ac88bb52ce6920f9e0
Autor:
Dane Donegan, Christoph M. Kanzler, Julia Büscher, Paulius Viskaitis, Ed F. Bracey, Olivier Lambercy, Denis Burdakov
Publikováno v:
J Neurosci
The ability to perform skilled arm movements is central to everyday life, as limb impairments in common neurologic disorders such as stroke demonstrate. Skilled arm movements require adaptation of motor commands based on discrepancies between desired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37bb3403fbbee888bc29753c43fdea8
https://doi.org/10.1523/jneurosci.0705-22.2022
https://doi.org/10.1523/jneurosci.0705-22.2022
Lateral hypothalamic (LH) hypocretin/orexin neurons (HONs) control brain-wide electrical excitation. Abnormally high excitation produces epileptic seizures, which affect millions of people and need better treatments. HON population activity spikes fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c202f5263ef14f8e3b21a9a642f66fd
https://doi.org/10.1101/2023.05.18.541308
https://doi.org/10.1101/2023.05.18.541308
