Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Denielli Da Silva Goncalves Bos"'
Autor:
Peng Zhang, Denielli Da Silva Goncalves Bos, Alexander Vang, Julia Feord, Danielle J. McCullough, Alexsandra Zimmer, Natalie D'Silva, Richard T. Clements, Gaurav Choudhary
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Reduced exercise capacity in pulmonary hypertension (PH) significantly impacts quality of life. However, the cause of reduced exercise capacity in PH remains unclear. The objective of this study was to investigate whether intrinsic skeletal
Externí odkaz:
https://doaj.org/article/121e8e70e2a144189447e92323cadc38
Autor:
Chris Happé, Kondababu Kurakula, Xiao-Qing Sun, Denielli da Silva Goncalves Bos, Nina Rol, Christophe Guignabert, Ly Tu, Ingrid Schalij, Karien C. Wiesmeijer, Olga Tura-Ceide, Anton Vonk Noordegraaf, Frances S. de Man, Harm Jan Bogaard, Marie-José Goumans
Publikováno v:
Cells, Vol 9, Iss 6, p 1422 (2020)
Background: Mutations in bone morphogenetic protein receptor type II (BMPR2) are leading to the development of hereditary pulmonary arterial hypertension (PAH). In non-hereditary forms of PAH, perturbations in the transforming growth factor-β (TGF-
Externí odkaz:
https://doaj.org/article/0258be1fdecb410e89fae97cee3ce1ca
Autor:
Denielli da Silva Goncalves Bos, Robert Szulcek, Frances S. de Man, Xiaoke Pan, Maria Catalina Gomez-Puerto, Willem J. van der Laarse, Ingrid Schalij, Anton Vonk Noordegraaf, Harm Jan Bogaard, Roy E. J. Schiepers, Eva L. Peters, Stine Andersen, Asger Andersen, Marie-José Goumans, Xiao-Qing Sun, Julie Birkmose Axelsen, Kondababu Kurakula
Publikováno v:
Sun, X-Q, Peters, E L, Schalij, I, Axelsen, J B, Andersen, S, Kurakula, K, Gomez-Puerto, M C, Szulcek, R, Pan, X, da Silva Goncalves Bos, D, Schiepers, R E, Andersen, A, Goumans, M-J, Vonk Noordegraaf, A, van der Laarse, W J, de Man, F S & Bogaard, H J 2021, ' Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension ', American Journal of Respiratory Cell and Molecular Biology (Online), vol. 64, no. 3, pp. 331-343 . https://doi.org/10.1165/rcmb.2020-0105OC
American Journal of Respiratory Cell and Molecular Biology, 64(3), 331-343. American Thoracic Society
Sun, X-Q, Peters, E L, Schalij, I, Axelsen, J B, Andersen, S, Kurakula, K, Gomez-Puerto, M C, Szulcek, R, Pan, X, da Silva Goncalves Bos, D, Schiepers, R E J, Andersen, A, Goumans, M-J, Noordegraaf, A V, van der Laarse, W J, de Man, F S & Bogaard, H J 2021, ' Increased MAO-A activity promotes progression of pulmonary arterial hypertension ', American Journal of Respiratory Cell and Molecular Biology, vol. 64, no. 3, pp. 331-343 . https://doi.org/10.1165/rcmb.2020-0105OC, https://doi.org/10.1165/rcmb.2020-0105OC
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, 64(3), 331-343. AMER THORACIC SOC
American Journal of Respiratory Cell and Molecular Biology, 64(3), 331-343. American Thoracic Society
Sun, X-Q, Peters, E L, Schalij, I, Axelsen, J B, Andersen, S, Kurakula, K, Gomez-Puerto, M C, Szulcek, R, Pan, X, da Silva Goncalves Bos, D, Schiepers, R E J, Andersen, A, Goumans, M-J, Noordegraaf, A V, van der Laarse, W J, de Man, F S & Bogaard, H J 2021, ' Increased MAO-A activity promotes progression of pulmonary arterial hypertension ', American Journal of Respiratory Cell and Molecular Biology, vol. 64, no. 3, pp. 331-343 . https://doi.org/10.1165/rcmb.2020-0105OC, https://doi.org/10.1165/rcmb.2020-0105OC
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, 64(3), 331-343. AMER THORACIC SOC
Monoamine oxidases (MAOs), a class of enzymes bound to the outer mitochondrial membrane, are important sources of reactive oxygen species. Increased MAO-A activity in endothelial cells and cardiomyocytes contributes to vascular dysfunction and progre
Autor:
Ly Tu, Franziska Herrmann, Xiaoke Pan, Robert Szulcek, Frances S. de Man, Anton Vonk-Noordegraaf, Geerten P. van Nieuw Amerongen, Harm Jan Bogaard, Chris Dickhoff, Kondababu Kurakula, Christophe Guignabert, Michiel Alexander de Raaf, Denielli da Silva Goncalves Bos, Nina Rol, Vincent P Kuiper, Kirsten Lodder, Xiaoqing Q Sun, Pieter Koolwijk, Chris Happé, Ingrid Schalij, Raphaël Thuillet, Marie-José Goumans, Lutz Wollin
Publikováno v:
Cardiovascular Research, 115(2), 432-439. Oxford University Press
Rol, N, de Raaf, M A, Sun, X Q, Kuiper, V P, da Silva Gonçalves Bos, D, Happé, C, Kurakula, K, Dickhoff, C, Thuillet, R, Tu, L, Guignabert, C, Schalij, I, Lodder, K, Pan, X, Herrmann, F E, van Nieuw Amerongen, G P, Koolwijk, P, Vonk-Noordegraaf, A, de Man, F S, Wollin, L, Goumans, M-J, Szulcek, R & Bogaard, H J 2019, ' Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension ', Cardiovascular Research, vol. 115, no. 2, pp. 432-439 . https://doi.org/10.1093/cvr/cvy186, https://doi.org/10.1093/cvr/cvy186
Cardiovascular Research, 115(2), 432-439. OXFORD UNIV PRESS
Rol, N, de Raaf, M A, Sun, X Q, Kuiper, V P, da Silva Gonçalves Bos, D, Happé, C, Kurakula, K, Dickhoff, C, Thuillet, R, Tu, L, Guignabert, C, Schalij, I, Lodder, K, Pan, X, Herrmann, F E, van Nieuw Amerongen, G P, Koolwijk, P, Vonk-Noordegraaf, A, de Man, F S, Wollin, L, Goumans, M-J, Szulcek, R & Bogaard, H J 2019, ' Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension ', Cardiovascular Research, vol. 115, no. 2, pp. 432-439 . https://doi.org/10.1093/cvr/cvy186, https://doi.org/10.1093/cvr/cvy186
Cardiovascular Research, 115(2), 432-439. OXFORD UNIV PRESS
Aims: Pulmonary arterial hypertension (PAH) is associated with increased levels of circulating growth factors and corresponding receptors such as platelet derived growth factor, fibroblast growth factor and vascular endothelial growth factor. Ninteda
Autor:
Peng Zhang, Ana Fernandez Nicolas, Gaurav Choudhary, Alexander Vang, Richard T. Clements, Thomas Mancini, Denielli da Silva Goncalves Bos
Publikováno v:
Circulation. 142
Introduction: Pulmonary arterial hypertension (PAH) is characterized by severe pulmonary vascular remodeling. Transition of endothelial cells (EC) to mesenchymal cells (EndMT) contributes to vascular remodeling; however, the role of EndMT and underly
Autor:
Celso R. F. Carvalho, Andrey Wirgues, Adriana Claudia Lunardi, Rafael Stelmach, Cibele Berto, Alberto Cukier, Fabiana Kim, Patricia Duarte Freitas, Denielli Da Silva Goncalves Bos, Jaqueline Rocha
Publikováno v:
Rehabilitation and chronic care.
Aerobic and respiratory exercises are non-pharmacological treatments recommended to improve asthma clinical control; however, the association of both interventions has never been tested. Aim: To assess the effect of aerobic and breathing exercises on
Autor:
Denielli da Silva Goncalves Bos, Harm Jan Bogaard, Karien C. Wiesmeijer, Chris Happé, Nina Rol, Kondababu Kurakula, Ingrid Schalij, Ly Tu, Anton Vonk Noordegraaf, Marie-José Goumans, Frances S. de Man, Olga Tura-Ceide, Xiao Qing Sun, Christophe Guignabert
Publikováno v:
Cells
Volume 9
Issue 6
Happé, C, Kurakula, K, Sun, X Q, da Silva Goncalves Bos, D, Rol, N, Guignabert, C, Tu, L, Schalij, I, Wiesmeijer, K C, Tura-Ceide, O, Vonk Noordegraaf, A, de Man, F S, Bogaard, H J & Goumans, M J 2020, ' The BMP Receptor 2 in Pulmonary Arterial Hypertension : When and Where the Animal Model Matches the Patient ', Cells, vol. 9, no. 6 . https://doi.org/10.3390/cells9061422
Cells, Vol 9, Iss 1422, p 1422 (2020)
Cells, 9(6). MDPI Multidisciplinary Digital Publishing Institute
Cells, 9(6). MDPI
Volume 9
Issue 6
Happé, C, Kurakula, K, Sun, X Q, da Silva Goncalves Bos, D, Rol, N, Guignabert, C, Tu, L, Schalij, I, Wiesmeijer, K C, Tura-Ceide, O, Vonk Noordegraaf, A, de Man, F S, Bogaard, H J & Goumans, M J 2020, ' The BMP Receptor 2 in Pulmonary Arterial Hypertension : When and Where the Animal Model Matches the Patient ', Cells, vol. 9, no. 6 . https://doi.org/10.3390/cells9061422
Cells, Vol 9, Iss 1422, p 1422 (2020)
Cells, 9(6). MDPI Multidisciplinary Digital Publishing Institute
Cells, 9(6). MDPI
Background: Mutations in bone morphogenetic protein receptor type II (BMPR2) are leading to the development of hereditary pulmonary arterial hypertension (PAH). In non-hereditary forms of PAH, perturbations in the transforming growth factor-&beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ba0bf645066a015e6a4fe4b1bd6f04
https://hdl.handle.net/1887/3182733
https://hdl.handle.net/1887/3182733
Autor:
Xiao Qing Sun, Adenauer G. Casali, Nina Rol, Jolanda van der Velden, Marie-José Goumans, Diederik W. D. Kuster, Denielli da Silva Goncalves Bos, Christophe Guignabert, Robert Szulcek, Frances S. de Man, Ly Tu, Anton Vonk-Noordegraaf, M. Louis Handoko, Marc Humbert, Harm Jan Bogaard, Kondababu Kurakula, Paul J.M. Wijnker, Karina Rabello Casali, Cris dos Remedios, Cathelijne E. E. van der Bruggen, Peter Dorfmüller
Publikováno v:
Da Silva Gonçalves Bós, D, Van Der Bruggen, C E E, Kurakula, K, Sun, X Q, Casali, K R, Casali, A G, Rol, N, Szulcek, R, Dos Remedios, C, Guignabert, C, Tu, L, Dorfmüller, P, Humbert, M, Wijnker, P J M, Kuster, D W D, Van Der Velden, J, Goumans, M J, Bogaard, H J, Vonk-Noordegraaf, A, De Man, F S & Handoko, M L 2018, ' Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension ', Circulation, vol. 137, no. 9, pp. 910-924 . https://doi.org/10.1161/CIRCULATIONAHA.117.027451
Circulation, 137(9), 910-924. Lippincott Williams and Wilkins
Circulation, 137(9), 910-924. Lippincott Williams and Wilkins
Background: The beneficial effects of parasympathetic stimulation have been reported in left heart failure, but whether it would be beneficial for pulmonary arterial hypertension (PAH) remains to be explored. Here, we investigated the relationship be
Autor:
Ly Tu, Frances S. de Man, Harm Jan Bogaard, Raphaël Thuillet, Julian F. R. Paton, M. Louis Handoko, Anton Vonk-Noordegraaf, Christophe Guignabert, Ingrid Schalij, Denielli da Silva Goncalves Bos, Chris Happé, Wioletta Pijacka, Albert C. van Rossum
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 1, Pp 22-35 (2017)
Jacc. Basic to Translational Science
da Silva Gonçalves Bos, D, Happé, C, Schalij, I, Pijacka, W, Paton, J F R, Guignabert, C, Tu, L, Thuillet, R, Bogaard, H J, van Rossum, A C, Vonk-Noordegraaf, A, de Man, F S & Handoko, M L 2017, ' Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension ', JACC: Basic to Translational Science, vol. 2, no. 1, pp. 22-35 . https://doi.org/10.1016/j.jacbts.2016.09.007
da Silva Gonçalves Bos, D, Happé, C, Schalij, I, Pijacka, W, Paton, J F R, Guignabert, C, Tu, L, Thuillet, R, Bogaard, H-J, van Rossum, A C, Vonk-Noordegraaf, A, de Man, F S & Handoko, M L 2017, ' Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension ', JACC: Basic to Translational Science, vol. 2, no. 1, pp. 22–35 . https://doi.org/10.1016/j.jacbts.2016.09.007
JACC: Basic to Translational Science, 2(1), 22-35. Elsevier Inc.
Jacc. Basic to Translational Science
da Silva Gonçalves Bos, D, Happé, C, Schalij, I, Pijacka, W, Paton, J F R, Guignabert, C, Tu, L, Thuillet, R, Bogaard, H J, van Rossum, A C, Vonk-Noordegraaf, A, de Man, F S & Handoko, M L 2017, ' Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension ', JACC: Basic to Translational Science, vol. 2, no. 1, pp. 22-35 . https://doi.org/10.1016/j.jacbts.2016.09.007
da Silva Gonçalves Bos, D, Happé, C, Schalij, I, Pijacka, W, Paton, J F R, Guignabert, C, Tu, L, Thuillet, R, Bogaard, H-J, van Rossum, A C, Vonk-Noordegraaf, A, de Man, F S & Handoko, M L 2017, ' Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension ', JACC: Basic to Translational Science, vol. 2, no. 1, pp. 22–35 . https://doi.org/10.1016/j.jacbts.2016.09.007
JACC: Basic to Translational Science, 2(1), 22-35. Elsevier Inc.
Visual Abstract
Highlights • Neurohormonal dysfunction (increased sympathetic nervous system and renin angiotensin-aldosterone system) play an important role in pulmonary hypertension progression. • In this proof-of-concept study we demonstr
Highlights • Neurohormonal dysfunction (increased sympathetic nervous system and renin angiotensin-aldosterone system) play an important role in pulmonary hypertension progression. • In this proof-of-concept study we demonstr
Autor:
Denielli Da Silva Goncalves Bos, Luciana Tamie Kato Morinaga, Rafael Taminato Hirata, Celso R. F. Carvalho, Amanda Rocha Diniz Kimura, Ana Clara Tude Rodrigues, Rogério Souza, José L. Andrade
Publikováno v:
Pulmonary hypertension.
Pulmonary arterial hypertension (PAH) is a fatal disease which leads to a reduction in physical activity levels (PAL). Schistosomiasis associated-PAH (Sch-PAH) is one of the most prevalent forms of PAH in developing countries. Previously, we demonstr